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Showing 1-20 of 569 results

  1. Clinical characteristics of patients with suspected Alzheimer’s disease within a CSF Aß-ratio grey zone

    Background

    The AT(N) research framework for Alzheimer's disease (AD) remains unclear on how to best deal with borderline cases. Our aim was to...

    Dariia Yosypyshyn, Domantė Kučikienė, ... Ana Sofia Costa in Neurological Research and Practice
    Article Open access 03 August 2023

  2. Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer’s disease amyloidosis

    Synaptic dysfunction is a likely proximate cause of subtle cognitive impairment in early Alzheimer’s disease. Soluble oligomers are the most...

    Yingjie Qi, Igor Klyubin, ... Michael J. Rowan in Neuropsychopharmacology
    Article Open access 29 June 2021

  3. Classification of negative and positive 18F-florbetapir brain PET studies in subjective cognitive decline patients using a convolutional neural network

    Purpose

    Visual reading of 18 F-florbetapir positron emission tomography (PET) scans is used in the diagnostic process of patients with cognitive...

    Bart Marius de Vries, Sandeep S. V. Golla, ... Ronald Boellaard in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 02 September 2020

  4. Evolution of neurodegeneration in patients with normal pressure hydrocephalus: a monocentric follow up study

    Background

    The aim of this study was to examine in patients with idiopathic and neurodegenerative normal pressure hydrocephalus (NPH) if motor and...

    Leonard L. Klemke, Katharina Müller-Schmitz, ... Rüdiger J. Seitz in Neurological Research and Practice
    Article Open access 07 September 2023

  5. Cerebral Superficial Siderosis

    Superficial siderosis (SS) of the central nervous system constitutes linear hemosiderin deposits in the leptomeninges and the superficial layers of...

    Stefan Weidauer, Elisabeth Neuhaus, Elke Hattingen in Clinical Neuroradiology
    Article Open access 28 November 2022

  6. Health related quality of life of patients undergoing in-centre hemodialysis in Rwanda: a cross sectional study

    Background:

    There are few studies assessing the quality of life of patients with chronic and end stage kidney disease in sub-Saharan Africa. We aimed...

    Gloria Shumbusho, Celestin Hategeka, ... Marla McKnight in BMC Nephrology
    Article Open access 27 October 2022

  7. Unraveling Alzheimer’s: the promise of aducanumab, lecanemab, and donanemab

    Alzheimer’s disease (AD) is a neurodegenerative condition that causes cognitive decline, memory loss, and reduced personal autonomy. The pathology of...

    Taha Basit Ameen, Syeda Naveera Kashif, ... Abdul Raheem in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
    Article Open access 14 June 2024

  9. Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer’s disease pathology progression

    A recent large genome-wide association study has identified EGFR (encoding the epidermal growth factor EGFR) as a new genetic risk factor for...

    Kunie Ando, Fahri Küçükali, ... Karelle Leroy in Acta Neuropathologica
    Article Open access 04 June 2024

  11. Neurodegeneration or dysfunction in Phelan-McDermid syndrome? A multimodal approach with CSF and computational MRI

    Background

    Phelan-McDermid syndrome (PMS) is a rare multisystem disease with global developmental delay and autistic features. Genetically, the...

    Sarah Jesse, Hans-Peter Müller, ... Jan Kassubek in Orphanet Journal of Rare Diseases
    Article Open access 05 September 2023

  12. Literature Review: Mechanism, Indications, and Clinical Efficacy of Peripheral Nerve Stimulators in Lower Extremity Pain

    Purpose of Review

    Lower extremity pain is deemed by Center for Disease Control and Prevention (CDC) to be a significant source of chronic pain in...

    Qing Zhao Ruan, Jason Chang, ... Christopher L. Robinson in Current Pain and Headache Reports
    Article 21 March 2024

  13. Immunotherapies Targeting Amyloid and Tau Protein in Alzheimer’s Disease: Should We Move Away from Diseases and Focus on Biological Targets? A Systematic Review and Expert Opinion

    Introduction

    Alzheimer’s disease (AD) is the most common cause of dementia worldwide, making it a major public health issue. Anti-amyloid and anti-tau...

    Arthur Esquer, Frédéric Blanc, Nicolas Collongues in Neurology and Therapy
    Article Open access 09 October 2023

  15. Die urologischen Fallberichte des Corpus Hippocraticum

    Objective

    Which theoretical and practical competences do the urologic case histories of the Hippocratic Corpus convey?

    Materials and methods ...
    Werner A. Golder in Die Urologie
    Article 18 March 2024

  16. Journal Club

    Peter Dovjak in Zeitschrift für Gerontologie und Geriatrie
    Article 08 February 2024

  17. „Keine Kapitulation vor den Schrecken der Dunkelheit!“

    Thomas Meißner in CME
    Article 11 March 2024

  18. N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease

    One mechanism of particular interest to regulate mRNA fate post-transcriptionally is mRNA modification. Especially the extent of m 1 A mRNA methylation...

    Marko Jörg, Johanna E. Plehn, ... Kristina Friedland in Molecular Psychiatry
    Article Open access 29 January 2024
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