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Plasma 8-OHdG act as a biomarker for steroid-induced osteonecrosis of the femoral head
BackgroundOxidative stress was closely related to the occurrence and development of Steroid-induced osteonecrosis of the femoral head (SIONFH)....
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Malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine (8-OHdG) in ischemic stroke: a systematic review
IntroductionThe low blood flow in ischemic stroke reduces oxygen and glucose and induces a series of reactions that produce free radicals. Free...
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A prospective case–control study on the evaluation of oxidative stress in renal stone formers
Association of increased oxidative stress (OS) with the pathophysiology of renal stone formation has not been explored greatly in the field of...
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Combination of urinary biomarkers and machine-learning models provided a higher predictive accuracy to predict long-term treatment outcomes of patients with interstitial cystitis/bladder pain syndrome
PurposeTo identify predictive factors for satisfactory treatment outcome of the patients with IC/BPS using urine biomarkers and machine-learning...
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SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway
AimsTo estimate the effects of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) on proteinuria and oxidative stress expression in type 2...
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Association of 8-hydroxy-2’-deoxyguanosine with motoric cognitive risk in elderly Chinese people: RUGAO longevity and aging cross-sectional study
BackgroundMotor cognitive risk syndrome (MCR) represents a critical pre-dementia and disability state characterized by a combination of objectively...
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Overnight changes in uric acid, xanthine oxidoreductase and oxidative stress levels and their relationships with sleep-disordered breathing in patients with coronary artery disease
Serum uric acid (UA) level is associated with the high cumulative incidence or prevalence of coronary artery disease (CAD), and hyperuricemia is...
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Association between atmospheric pollutant levels and oxidative stress in pregnant women and newborns in Urumqi
BackgroundFrequent heavy air pollution occurred during the winter heating season of northern China. Particulate air pollution is a serious concern in...
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Potential role of glutathione S‑transferase M1 gene polymorphism in kidney calcium oxalate stone formation
BackgroundThe purpose of this study was to look into the effects of glutathione S-transferase M1 ( GSTM1 ) gene polymorphism on the formation of...
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Diet diversity and food quality score in male football players and healthy non-athlete controls in relation to oxidative stress biomarkers: a descriptive-analytical study
BackgroundDietary patterns that include high-quality and varied food groups have the potential to modulate oxidative status. This research was...
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Aqueous humor and serum levels of 4-hydroxynonenal and 8-hydroxy-2′deoxyguanosine in pseudoexfoliation syndrome and glaucoma
PurposeTo compare the aqueous humor (AH) and serum levels of 4-hydroxynenal (4-HNE) and 8-hydroxy-2′-deoxyguanosine (8-OhdG) in patients with...
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PRDX1 exerts a photoprotection effect by inhibiting oxidative stress and regulating MAPK signaling on retinal pigment epithelium
BackgroundThe purpose of this study was to investigate the photoprotection effect of peroxiredoxin 1 (PRDX1) protein in ultraviolet B (UVB)...
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Serum 8-Hydroxy-2′-deoxyguanosine Predicts Severity and Prognosis of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
BackgroundOxidative stress is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). 8-Hydroxy-2′-deoxyguanosine (8-OHdG) is...
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Increased oxidative and chromosomal DNA damage in patients with ankylosing spondylitis: its role in pathogenesis
Increased DNA damage has been suggested to contribute to the pathogenesis of chronic inflammatory diseases, but controlled studies are lacking in...
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Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming
Childhood mental disorders, including emotional and behavioural problems (EBP) are increasingly prevalent. Higher maternal oxidative stress (OS)...
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The interplay between sexual abuse and inflammation, oxidative stress, and DNA damage in drug-naïve panic disorder patients
Although accumulating evidence suggests an interplay between child abuse and inflammatory processes and the pathophysiology of mental disorders, few...
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Repurposing fexofenadine as a promising candidate for diabetic kidney disease: randomized clinical trial
PurposeDiabetic kidney disease (DKD) is a devastating complication of diabetes mellitus. Inflammation and histamine are potentially involved in the...
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Hyperoxia but not high tidal volume contributes to ventilator-induced lung injury in healthy mice
BackgroundMechanical ventilation is a supportive therapy used to maintain respiratory function in several clinical and surgical cases but is always...
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Interaction between haptoglobin genotype and glycemic variability on diabetic macroangiopathy: a population-based cross-sectional study
PurposeHaptoglobin (Hp) is a hemoglobin-binding protein that functions as an antioxidant in human plasma. It is reported that glycemic variability...
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ErZhiTianGui Decoction alleviates age-related ovarian aging by regulating mitochondrial homeostasis and inhibiting ferroptosis
AimThis study was designed to investigate the pharmacological effects and mechanisms of ErZhiTianGui Decoction (EZTG) for age-related ovarian aging...
