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Showing 1-20 of 4,916 results
  1. Analysis of intestinal flora and cognitive function in maintenance hemodialysis patients using combined 16S ribosome DNA and shotgun metagenome sequencing

    Background

    Cognitive impairment is widely prevalent in maintenance hemodialysis (MHD) patients, and seriously affects their quality of life. The...

    Qiuyi Gao, Dianshi Li, ... Nan Wang in Aging Clinical and Experimental Research
    Article Open access 09 February 2024
  2. Delineation of the bacterial composition in exogenous endophthalmitis using 16S rDNA sequencing

    Purpose

    To determine the bacterial spectrum of exogenous endophthalmitis of different origins, namely, posttraumatic, postcataract surgery, filtering...

    Benxiang Qi, Bi Ning Zhang, ... Yusen Huang in International Ophthalmology
    Article 20 July 2022
  3. Concordance between culture, Molecular Culture and Illumina 16S rRNA gene amplicon sequencing of bone and ulcer bed biopsies in people with diabetic foot osteomyelitis

    Background

    In clinical practice the diagnosis of diabetic foot osteomyelitis (DFO) relies on cultures of bone or ulcer bed (UB) biopsies, of which...

    Meryl Cinzía Tila Tamara Gramberg, Carmen Knippers, ... Edgar Josephus Gerardus Peters in BMC Infectious Diseases
    Article Open access 01 August 2023
  4. 16S rRNA gene sequencing reveals the effect of fluoxetine on gut microbiota in chronic unpredictable stress-induced depressive-like rats

    Objectives

    Gut microbiota is relevant to the pathogenesis of mental disorders including depression. This study aimed to investigate the influence of...

    Hui Dong, **aowei Tang, ... Wenhuan **ao in Annals of General Psychiatry
    Article Open access 03 August 2023
  5. Changes in the fecal microbiota of breast cancer patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis

    Purpose

    Breast cancer (BC) is a devastating disease for women. Microbial influences may be involved in the development and progression of breast...

    Biqing Luan, Fei Ge, ... Wenlin Chen in Clinical and Translational Oncology
    Article 13 January 2024
  6. Alterations of gut microbiota in infants with biliary atresia identified by 16S rRNA-sequencing

    Background

    Biliary atresia (BA) is a severe neonatal disease with progressive intra- and extra-hepatic bile ducts inflammation and hepatic fibrosis....

    Fei Liu, Ru Wei, ... Jixiao Zeng in BMC Pediatrics
    Article Open access 14 February 2024
  7. Therapeutic intervention based on gene sequencing analysis of microbial 16S ribosomal RNA of the intrauterine microbiome improves pregnancy outcomes in IVF patients: a prospective cohort study

    Purpose

    A Lactobacillus -dominated microbiota in the endometrium was reported to be associated with favorable reproductive outcomes. We investigated...

    Nanako Iwami, Miho Kawamata, ... Hirobumi Kamiya in Journal of Assisted Reproduction and Genetics
    Article 19 December 2022
  8. 16S rRNA sequencing analysis of the oral and fecal microbiota in colorectal cancer positives versus colorectal cancer negatives in Iranian population

    Background

    Colorectal cancer (CRC) poses a significant healthcare challenge, accounting for nearly 6.1% of global cancer cases. Early detection,...

    Sama Rezasoltani, Mehdi Azizmohammad Looha, ... Mohammad Mehdi Feizabadi in Gut Pathogens
    Article Open access 20 February 2024
  9. Analysis of 16s rRNA Gene Sequencing in Feces: The Impact of Bariatric Surgery on the Gut Microbiota in Patients with Obesity

    Purpose

    Obesity is a risk factor for many chronic diseases. This study aimed to investigate the effect of bariatric surgery on the gut microbiota from...

    Lijun Zhang, **aolei Cheng, ... Jianhui Yin in Obesity Surgery
    Article 22 February 2024
  10. Comparison of 16S rRNA gene sequencing microbiota among children with serological IgE-mediated food hypersensitivity

    Background

    We hypothesized that specific food hypersensitivity (FH) in children is linked to specific gut microbiota. The aim of our study was to...

    Chien-Chang Chen, **g-Long Huang, ... Hung-Ju Chang in Pediatric Research
    Article 30 August 2023
  11. Routine use of 16S rRNA PCR and subsequent sequencing from blood samples in septic shock: about two case reports of Capnocytophaga canimorsus infection in immunocompetent patients

    Background

    Capnocytophaga canimorsus infection happens frequently in immunosuppressed patients with reported domestic animal bites. Clinical...

    Alexandre Martins-Baltar, Sylvain Meyer, ... Bruno François in BMC Infectious Diseases
    Article Open access 09 April 2022
  12. The gut microbiota composition in patients with right- and left-sided colorectal cancer and after curative colectomy, as analyzed by 16S rRNA gene amplicon sequencing

    Background

    Gut pathological microbial imbalance or dysbiosis is closely associated with colorectal cancer. Although there are observable differences...

    Daisuke Suga, Hiroki Mizutani, ... Katsuya Shiraki in BMC Gastroenterology
    Article Open access 25 June 2022
  13. 16S rRNA seq-identified Corynebacterium promotes pyroptosis to aggravate diabetic foot ulcer

    Background

    Diabetic foot ulcer (DFU) is one of the main chronic complications caused by diabetes, leading to amputation in severe cases. Bacterial...

    Hailong Zheng, Han Na, ... **aopan Chen in BMC Infectious Diseases
    Article Open access 01 April 2024
  14. 16S rRNA sequencing-based evaluation of the protective effects of Hua-Zhuo-Jie-Du on rats with chronic atrophic gastritis

    Background

    Disturbance of the intestinal flora is a pathogenic factor for chronic atrophic gastritis (CAG). Hua-Zhuo-Jie-Du (HZJD) has been shown to...

    **** Zhou, Tianxiao Yang, ... Yangang Wang in BMC Complementary Medicine and Therapies
    Article Open access 16 March 2022
  15. Impact of 16S rDNA sequencing on clinical treatment decisions: a single center retrospective study

    Background

    PCRs targeting 16S ribosomal DNA (16S PCR) followed by Sanger’s sequencing can identify bacteria from normally sterile sites and complement...

    Axel Ursenbach, Frédéric Schramm, ... Xavier Argemi in BMC Infectious Diseases
    Article Open access 18 February 2021
  16. Coinfection of Clostridium perfringens and Escherichia coli in gas-producing perianal abscess diagnosed by 16S rDNA sequencing: a case report

    Background

    Gas-producing perianal abscess raises the possibility of clostridial infection, with Clostridium perfringens being the most common...

    Yang Sun, Haotian Bai, ... Linlin Feng in Gut Pathogens
    Article Open access 13 October 2021
  17. Role of 16S Ribosomal RNA Analysis in Identification of Microorganisms in Febrile Urinary Tract Infection of Infants

    Objectives

    To assess the role of 16S ribosomal RNA analysis in microbial identification in febrile infants under six months of age diagnosed with UTI,...

    Jae Hong Choi, Young Mi Yoon, ... Kyoung Hee Han in Indian Journal of Pediatrics
    Article 14 March 2022
  18. Improved Diagnostics in Bacterial Neonatal Meningitis Using a Next-Generation Sequencing Platform

    Introduction

    Bacterial meningitis in infants is an infrequent but life-threatening condition. Empiric therapy should begin as soon as meningitis is...

    Alieke van der Hoeven, Martha T. van der Beek, ... Stefan A. Boers in Infectious Diseases and Therapy
    Article Open access 12 July 2023
  19. 16S rRNA gene amplicon sequencing of gut microbiota in gestational diabetes mellitus and their correlation with disease risk factors

    Purpose

    Although the gut microbiota (GM) are associated with various diseases, their role in gestational diabetes mellitus (GDM) remains...

    J. Wei, Y. Qing, ... J. Gao in Journal of Endocrinological Investigation
    Article Open access 24 July 2021
  20. Next-generation sequencing of 16S rRNA for identification of invasive bacterial pathogens in a formalin-fixed paraffin-embedded placental specimen: a case report of perinatal fulminant Streptococcus pyogenes infection

    Intrauterine infection is one of the most important causes of maternal death. In perinatal emergency, we often miss an opportunity to obtain culture...

    Tasuku Mariya, Toyotaka Sato, ... Tsuyoshi Saito in Medical Molecular Morphology
    Article 21 July 2021
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