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Person-centred medicine in the care home setting: development of a complex intervention
BackgroundPerson-centred medicine is recommended in the care of older patients. Yet, involvement of care home residents and relatives in medication...
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An interdisciplinary intervention for children and adolescents with multiple referrals and complex health complaints: a feasibility study
BackgroundChildren and adolescents with complex health complaints are often referred to several different healthcare specialists for assessments and...
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Development of a complex Interdisciplinary Nurse-coordinated SELf-MAnagement (INSELMA) intervention for patients with inflammatory arthritis
BackgroundApart from a consistent focus on treating inflammation, patients with inflammatory arthritis (IA) report a range of unmet needs. Many...
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Recommendations for successful involvement of patient partners in complex intervention research: a collaborative learning process
BackgroundPatient and public involvement in health-related research is a new discipline in Denmark. In 2021, a national conference titled 'Patient...
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Newly diagnosed with inflammatory arthritis (NISMA)–development of a complex self-management intervention
BackgroundPatients newly diagnosed with inflammatory arthritis (IA) request regular consultations and support from health professionals to manage...
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Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia
IntroductionFirst-line treatment for behavioral and psychiatric symptoms of dementia is non-pharmacological. Still, psychotropic medication is widely...
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Pragmatic randomized controlled trial comparing a complex telemedicine-based intervention with usual care in patients with chronic conditions
This study evaluates a complex telemedicine-based intervention targeting patients with chronic health problems. Computer tablets and home...
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Complex Cases in Structural Heart Intervention
Structural heart disease encompasses a wide range of abnormalities involving noncoronary structures like the heart's valves, walls, and chambers. The...
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Adapting a complex violence prevention intervention: a case study of the Good School Toolkit in Uganda
BackgroundAdaptation is a key strategy to extend the reach of evidence-based interventions to prevent violence in new populations, but there is a...
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An iterative approach to develo** a multifaceted implementation strategy for a complex eHealth intervention within clinical practice
BackgroundThe number of complex eHealth interventions has increased considerably. Despite available implementation theory outlining well-designed...
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Complex and high-risk intervention in indicated patients (CHIP) in contemporary clinical practice
Recently, there has been a growing interest in the concept of complex and high-risk intervention in indicated patients (CHIP). In our previous...
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Retrospective review comparing intrapleural fibrinolytic therapy (alteplase) and surgical intervention in complex pleural effusion
BackgroundIntrapleural fibrinolytic therapy (IPFT) is one of the treatment options for complex pleural effusion. In this study, the IPFT agent used...
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Quality of sick child management by health extension workers: role of a complex improvement intervention
BackgroundDespite the expansion of the Integrated Community Case Management services for childhood illness, quality and utilization of services have...
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A data-driven approach to implementing the HPTN 094 complex intervention INTEGRA in local communities
BackgroundHIV burden in the US among people who inject drugs (PWID) is driven by overlap** syndemic factors such as co-occurring health needs and...
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A novel tapered guide extension catheter facilitated successful completion of complex percutaneous coronary intervention
BackgroundGuide extension catheters (GEC) are widely applied to cope with insufficient backup support in complex percutaneous coronary intervention...
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Co-creation of a complex, multicomponent rehabilitation intervention and feasibility trial protocol for the PostUraL tachycardia Syndrome Exercise (PULSE) study
BackgroundThere is a dearth of research to support the treatment of people with postural tachycardia syndrome (PoTS). Despite expert consensus...
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A complex intervention on vaccination uptake among older adults (≥ 60 years) in Germany – a study protocol with a mixed methods design
BackgroundThe current uptake of many vaccinations recommended for persons aged 60 and older is unsatisfactory in Germany. Lack of confidence in the...
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Salutogenic Healthy Ageing Programme Embracement (SHAPE)- an upstream health resource intervention for older adults living alone and with their spouses only: complex intervention development and pilot randomized controlled trial
BackgroundIn view of age-related health concerns and resource vulnerabilities challenging older adults to age in place, upstream health resource...
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A randomised controlled trial of the Learning Skills Together (LST) intervention to improve dementia family caregivers’ self-efficacy with complex care
BackgroundNearly two-thirds of family caregivers of persons living with Alzheimer’s disease or related dementias (AD/ADRD) provide complex care,...
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A multicomponent complex intervention for supportive follow-up of persons with chronic heart failure: a randomized controlled pilot study (the UTILE project)
BackgroundHeart failure (HF) is a progressive disease associated with a high burden of symptoms, high morbidity and mortality, and low quality of...