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Potentially effective natural drugs in treatment for the most common rheumatic disorder: osteoarthritis
Osteoarthritis (OA) is a chronic condition in which imbalance between anabolic and catabolic mediators occurs leading to the destruction of...
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Monocyclic and dicyclic hydrocarbons: structural requirements for proximal giant axonopathy
The chromogenic and neurotoxic γ-diketone 1,2–diacetylbenzene (1,2-DAB), but not its isomer 1,3-DAB, induces blue discoloration of tissues and urine,...
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A new murine model of giant proximal axonopathy
The aromatic γ-diketone 1,2-diacetylbenzene (1,2-DAB), the putative active metabolite of the organic solvent 1,2-diethylbenzene, forms blue-colored...
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Distal axonopathy does not occur without neurofilament accumulation in γ-diketone neuropathy: comparative studies of normal and neurofilament-deficient quail
The neurotoxic effects caused by chronic exposure to 2,5-hexanedione (2,5-HD) were investigated in normal and neurofilament (NF)-deficient quail...