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Pre-treatment 68 Ga-PSMA-11 PET/CT Prognostic Value in Predicting Response to 177Lu-PSMA-I&T Therapy and Patient Survival
PurposeTo assess the prognostic value of pre-treatment [ 68 Ga]Ga-PSMA-11 PET/CT and other baseline clinical characteristics in predicting prostate...
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Total-body [68 Ga]Ga-PSMA-11 PET/CT improves detection rate compared with conventional [68 Ga]Ga-PSMA-11 PET/CT in patients with biochemical recurrent prostate cancer
PurposeThe purpose of this study was to assess whether total-body [ 68 Ga]Ga-PSMA-11 PET/CT could improve the detection rate compared with...
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Evaluation of [68 Ga]Ga-PSMA-I&T PET/CT with additional late scans of the pelvis in prostate-specific antigen recurrence using the PROMISE criteria
BackgroundPSMA PET/CT is the recommended imaging test in cases with prostate-specific antigen (PSA) recurrence after primary therapy of prostate...
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A novel PSMA-targeting tracer with highly negatively charged linker demonstrates decreased salivary gland uptake in mice compared to [68Ga]Ga-PSMA-11
BackgroundThe current generation of radiolabeled PSMA-targeting therapeutic agents is limited by prominent salivary gland binding, which results in...
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Evaluating the biodistribution for [68Ga]Ga-PSMA-11 and [18F]F-PSMA-1007 PET/CT with an inter- and intrapatient based analysis
BackgroundLiver uptake in [ 68 Ga]Ga-PSMA-11 PET is used as an internal reference in addition to clinical parameters to select patients for [ 177 Lu]Lu-P...
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The superior detection rate of total-body [68Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [68Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA < 0.2 ng/mL after radical prostatectomy
Background and purpose[ 68 Ga]Ga-PSMA PET imaging has been extensively utilized for the detection of biochemical recurrence (BCR) in prostate cancer....
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Assessing dynamic metabolic heterogeneity in prostate cancer patients via total-body [68Ga]Ga-PSMA-11 PET/CT imaging: quantitative analysis of [68Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs
PurposeThis study aimed to quantitatively assess [ 68 Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs in prostate cancer using the...
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Automated radiolabelling of [68Ga]Ga-PSMA-11 (gallium (68Ga)-gozetotide) using the Locametz® kit and two generators
BackgroundSteps have been taken by pharmaceutical companies to obtain marketing authorisation of PSMA ligands in the European Union. Since December...
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A prospective comparative study of [68Ga]Ga-RM26 and [68Ga]Ga-PSMA-617 PET/CT imaging in suspicious prostate cancer
PurposeProstate-specific membrane antigen (PSMA)–based PET/CT imaging has limitations in the diagnosis of prostate cancer (PCa). We recruited 207...
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Diverse PSMA expression in primary prostate cancer: reason for negative [68Ga]Ga-PSMA PET/CT scans? Immunohistochemical validation in 40 surgical specimens
PurposeThe purpose of this study was to immunohistochemically validate the primary tumor PSMA expression in prostate cancer (PCa) patients imaged...
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The image quality and feasibility of solitary delayed [68 Ga]Ga-PSMA-11 PET/CT using long field-of-view scanning in patients with prostate cancer
BackgroundPrevious studies have demonstrated that delayed [ 68 Ga]Ga-PSMA PET/CT imaging improves lesion detection compared to early [ 68 Ga]Ga-PSMA...
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A prospective head-to-head comparison of [68Ga]Ga-P16-093 and [68Ga]Ga-PSMA-11 PET/CT in patients with primary prostate cancer
PurposeWe aimed to compare the diagnostic performance and biodistribution of two similar PET agents, [ 68 Ga]Ga-P16-093 and [ 68 Ga]Ga-PSMA-11, in the...
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[68Ga]Ga‑LNC1007 PET/CT in the evaluation of renal cell carcinoma: comparison with 2-[18F]FDG/[68Ga]Ga-PSMA PET/CT
PurposeTo compare the potential efficiency of [ 68 Ga]Ga-LNC1007 with 2-[ 18 F]FDG/[ 68 Ga]Ga-PSMA PET/CT for detecting renal cell carcinoma (RCC) and to...
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A convolutional neural network–based system for fully automatic segmentation of whole-body [68Ga]Ga-PSMA PET images in prostate cancer
PurposeThe aim of this study was development and evaluation of a fully automated tool for the detection and segmentation of mPCa lesions in...
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Comparison of parametric imaging and SUV imaging with [68 Ga]Ga-PSMA-11 using dynamic total-body PET/CT in prostate cancer
PurposeStandardized uptake value (SUV) has been prevalently used to measure [ 68 Ga]Ga-PSMA-11 activity in prostate cancer, but it is susceptible to...
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Automated segmentation of lesions and organs at risk on [68Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR
BackgroundProstate-specific membrane antigen (PSMA) PET/CT imaging is widely used for quantitative image analysis, especially in radioligand therapy...
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Role of [68Ga]Ga-PSMA-11 PET radiomics to predict post-surgical ISUP grade in primary prostate cancer
PurposeThe aim of this study is to investigate the role of [ 68 Ga]Ga-PSMA-11 PET radiomics for the prediction of post-surgical International Society...
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Deep learning–based whole-body characterization of prostate cancer lesions on [68Ga]Ga-PSMA-11 PET/CT in patients with post-prostatectomy recurrence
PurposeThe automatic segmentation and detection of prostate cancer (PC) lesions throughout the body are extremely challenging due to the lesions’...
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Meta-analysis of 18 F-PSMA-1007 PET/CT, 18 F-FDG PET/CT, and 68Ga-PSMA PET/CT in diagnostic efficacy of prostate Cancer
ObjectiveTo compare 18 F-PSMA-1007 PET/CT, 18 F-FDG PET/CT and 68 Ga-PSMA PET/CT in the diagnostic value of prostate cancer.
MethodThe Chinese and...
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Comparison of tracer kinetic models for 68Ga-PSMA-11 PET in intermediate-risk primary prostate cancer patients
Background68 Ga-PSMA-11 positron emission tomography enables the detection of primary, recurrent, and metastatic prostate cancer. Regional...