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Screening of antigenic epitopes related to the adhesion of the avian Escherichia coli Type 1 Fimbrial Agglutinin Domain
BackgroundAvian Escherichia coli ( E.coli ) type 1 fimbriae adhere to avian tracheal epithelial cells through the FimH protein. However, the...
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Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report
BackgroundCold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...
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New predictors of microvascular invasion for small hepatocellular carcinoma ≤ 3 cm
BackgroundMicrovascular invasion (MVI) is a risk factor for postoperative recurrence of hepatocellular carcinoma (HCC), even in early-stage HCC. In...
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GALAD score as a prognostic model for recurrence of hepatocellular carcinoma after local ablation
BackgroundCurrently, the high recurrence rate still forms severe challenges in hepatocellular carcinoma (HCC) treatment. The GALAD score, including...
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Sutimlimab: First Approval
Sutimlimab (sutimlimab-jome; ENJAYMO™) is a humanized monoclonal antibody developed by Sanofi for the treatment of cold agglutinin disease (CAD)....
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Autoimmune Hemolytic Anemia in Children: Clinical Profile and Outcome
ObjectiveTo discover the common triggers for AIHA in children, their clinical profile, treatment response, and outcome.
MethodsThis was an...
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Real-world efficacy and safety of glecaprevir/pibrentasvir in Japanese adolescents with chronic hepatitis C: a prospective multicenter study
BackgroundPart 1 of the DORA study, a 2019 international clinical trial of glecaprevir and pibrentasvir (G/P) treatment in adolescents with chronic...
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Cough Hypersensitivity Syndrome Following Whoo** Cough Showing Persistent Hypercytokinemia with Autoimmune Feature in Relation to Genetic Hypohaptoglobinemia: a Case Report
Whoo** cough is a well-known contagious disease caused by the Gram-negative bacterium Bordetella pertussis . The pathogenesis of whoo** cough is...
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Shexiang Tongxin Drop** Pill Promotes Angiogenesis through VEGF/eNOS Signaling Pathway on Diabetic Coronary Microcirculation Dysfunction
ObjectiveTo study the effect of Shexiang Tongxin Drop** Pill (STDP) on angiogenesis in diabetic cardiomyopathy mice with coronary microcirculation...
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C1GALT1 expression predicts a favorable prognosis and suppresses malignant phenotypes via TrkA signaling in neuroblastoma
Neuroblastoma (NB) is a childhood tumor derived from the sympathoadrenal lineage of the neural crest progenitor cells. Core 1...
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Total arch replacement for an aortic arch aneurysm with cold agglutinin disease after rituximab and plasmapheresis
BackgroundCold agglutinin disease can lead to significant complications, especially for patients undergoing arch repair requiring hypothermic...
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Cold-antibody Autoimmune Hemolytic Anemia: its Association with Neoplastic Disease and Impact on Therapy
Purpose of ReviewCold-antibody mediated autoimmune hemolytic anemia (cAIHA) is subclassified as cold agglutinin disease (CAD), secondary cold...
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Legume Allergens Pea, Chickpea, Lentil, Lupine and Beyond
Purpose of the ReviewIn the last decade, an increasing trend towards a supposedly healthier vegan diet could be observed. However, recently, more...
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Clinical Profile and Outcome of Childhood Autoimmune Hemolytic Anemia: A Single Center Study
ObjectiveTo analyze clinical and laboratory parameters, and treatment outcomes of children with autoimmune hemolytic anemia (AIHA).
Methods ... -
Abnormalities in lysine degradation are involved in early cardiomyocyte hypertrophy development in pressure-overloaded rats
BackgroundCardiomyocyte metabolism changes before cardiac remodeling, but its role in early cardiac hypertrophy detection remains unclear. This study...
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A case of cold agglutinin syndrome associated with chronic lymphocytic leukaemia harbouring mutations in CARD11 and KMT2D
Cold agglutinin disease (CAD) is a rare cold autoimmune haemolytic anaemia (cAIHA) caused by IgM antibodies recognizing I antigens on erythrocytes....
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