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Effect of differences in O-RADS lexicon interpretation between senior and junior sonologists on O-RADS classification and diagnostic performance
PurposeTo assess the consistency of Ovarian-Adnexal Reporting and Data System (O-RADS) lexicon interpretation between senior and junior sonologists...
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O-GlcNAcylation is essential for therapeutic mitochondrial transplantation
BackgroundTransplantation of mitochondria is increasingly explored as a novel therapy in central nervous system (CNS) injury and disease. However,...
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O-GlcNAcylation of E3 ubiquitin ligase SKP2 promotes hepatocellular carcinoma proliferation
O-linked-β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) and ubiquitination are critical posttranslational modifications that...
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Extracardiac findings with increased perfusion during clinical O-15-H2O PET/CT myocardial perfusion imaging: A case series
BackgroundCoincidental extracardiac findings with increased perfusion were reported during myocardial perfusion imaging (MPI) with various retention...
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O-RADS MRI risk stratification system: pearls and pitfalls
In 2021, the American College of Radiology (ACR) Ovarian-Adnexal Reporting and Data System (O-RADS) MRI Committee developed a risk stratification...
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O-DEM: ein neues kognitives Screening bei Schwerhörigkeit
BackgroundHearing loss is a significant risk factor for dementia. To date, cognitive impairment and dementia in patients with hearing impairment (HI)...
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82Rb and [15O]H2O myocardial perfusion PET imaging: a prospective head to head comparison
Background82 Rb PET and [ 15 O]H 2 O PET are both validated tracers for myocardical perfusion imaging but have not previously been compared clinically....
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Adenosine-induced splenic switch-off on [15O]H2O PET perfusion for the assessment of vascular vasodilatation
BackgroundSplenic switch-off (SSO) is a marker of adequate adenosine-induced vasodilatation on cardiac magnetic resonance perfusion imaging. We...
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Repeatability of [15O]H2O PET imaging for lower extremity skeletal muscle perfusion: a test–retest study
Background[ 15 O]H 2 O PET/CT allows noninvasive quantification of tissue perfusion and can potentially play a future role in the diagnosis and...
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Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation
BackgroundO-GlcNAcylation is the enzymatic addition of a sugar, O-linked β-N-Acetylglucosamine, to the serine and threonine residues of proteins, and...
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Whole-body parametric map** of tumour perfusion in metastatic prostate cancer using long axial field-of-view [15O]H2O PET
PurposeTumour perfusion is a nutrient-agnostic biomarker for cancer metabolic rate. Use of tumour perfusion for cancer growth assessment has been...
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O-GlcNAcylation of melanophilin enhances radiation resistance in glioblastoma via suppressing TRIM21 mediated ubiquitination
The molecular mechanism of glioblastoma (GBM) radiation resistance remains poorly understood. The aim of this study was to elucidate the potential...
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O-RADS combined with contrast-enhanced ultrasound in risk stratification of adnexal masses
BackgroundOvarian-Adnexal Reporting and Data System (O-RADS) for ultrasound is a lexicon and risk stratification system that includes all risk...
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O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma
Aberrantly elevated O-GlcNAcylation level is commonly observed in human cancer patients, and has been proposed as a potential therapeutic target....
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O-GlcNAcylation: a pro-survival response to acute stress in the cardiovascular and central nervous systems
O-GlcNAcylation is a unique monosaccharide modification that is ubiquitously present in numerous nucleoplasmic and mitochondrial proteins. The...
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O-RADS MRI scoring system: key points for correct application in inexperienced hands
ObjectivesTo evaluate the efficacy of the O-RADS MRI criteria in the stratification of risk of malignancy of solid or sonographically indeterminate...
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High expression levels of centromere protein O participates in cell proliferation of human ovarian cancer
Ovarian cancer is a common malignant tumor in women, with a high mortality rate ranking first among gynecological tumors. Currently, there is...
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Validation of resting full-cycle ratio and diastolic pressure ratio with [15O]H2O positron emission tomography myocardial perfusion
Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are invasive techniques used to evaluate the hemodynamic significance of...
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B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
BackgroundB3GNT7, a glycosyltransferase of significant importance that is highly expressed in intestinal epithelial cells, plays a pivotal role in...
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Natural evidence of coronaviral 2′-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding
Previous studies through targeted mutagenesis of K-D-K-E motif have demonstrated that 2′-O-MTase activity is essential for efficient viral...
