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  1. Total-body [68 Ga]Ga-PSMA-11 PET/CT improves detection rate compared with conventional [68 Ga]Ga-PSMA-11 PET/CT in patients with biochemical recurrent prostate cancer

    Purpose

    The purpose of this study was to assess whether total-body [ 68 Ga]Ga-PSMA-11 PET/CT could improve the detection rate compared with...

    Yining Wang, Zijun Chen, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 14 August 2023
  2. The superior detection rate of total-body [68Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [68Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA < 0.2 ng/mL after radical prostatectomy

    Background and purpose

    [ 68 Ga]Ga-PSMA PET imaging has been extensively utilized for the detection of biochemical recurrence (BCR) in prostate cancer....

    Yining Wang, Liang Dong, ... Ruohua Chen in European Journal of Nuclear Medicine and Molecular Imaging
    Article 22 March 2024
  3. Retrospective analysis of thyroid incidentalomas detected by [68Ga]Ga-PSMA-11 PET/CT

    Background

    Prostate cancer patients, undergo imaging procedures, with [ 68 Ga]Ga-PSMA-11 PET/CT (prostate-specific membrane antigen based positron...

    İlkcan Çerçi Koçar, Pınar Pelin Özcan, ... Kerem Sezer in Endocrine
    Article 10 May 2024
  4. [89Zr]Zr-PSMA-617 PET/CT characterization of indeterminate [68Ga]Ga-PSMA-11 PET/CT findings in patients with biochemical recurrence of prostate cancer: lesion-based analysis

    Background

    The state-of-the-art method for imaging men with biochemical recurrence of prostate cancer (BCR) is prostate-specific membrane antigen...

    Florian Rosar, Caroline Burgard, ... Samer Ezziddin in Cancer Imaging
    Article Open access 22 February 2024
  5. Detection efficacy of [89Zr]Zr-PSMA-617 PET/CT in [68Ga]Ga-PSMA-11 PET/CT-negative biochemical recurrence of prostate cancer

    Rationale

    In patients with biochemical recurrence of prostate cancer (BCR), preliminary data suggest that prostate-specific membrane antigen (PSMA)...

    Florian Rosar, Fadi Khreish, ... Samer Ezziddin in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 06 May 2023
  6. Multiparametric dynamic whole-body PSMA PET/CT using [68Ga]Ga-PSMA-11 and [18F]PSMA-1007

    Background

    Routine prostate-specific membrane antigen (PSMA) positron emission tomography (PET) performed for primary staging or restaging of prostate...

    André H. Dias, Mads R. Jochumsen, ... Lars C. Gormsen in EJNMMI Research
    Article Open access 15 April 2023
  7. The image quality and feasibility of solitary delayed [68 Ga]Ga-PSMA-11 PET/CT using long field-of-view scanning in patients with prostate cancer

    Background

    Previous studies have demonstrated that delayed [ 68  Ga]Ga-PSMA PET/CT imaging improves lesion detection compared to early [ 68 Ga]Ga-PSMA...

    **aofeng Yu, Lian Xu, ... Yumei Chen in EJNMMI Research
    Article Open access 06 February 2024
  8. Assessing dynamic metabolic heterogeneity in prostate cancer patients via total-body [68Ga]Ga-PSMA-11 PET/CT imaging: quantitative analysis of [68Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs

    Purpose

    This study aimed to quantitatively assess [ 68 Ga]Ga-PSMA-11 uptake in pathological lesions and normal organs in prostate cancer using the...

    Ruohua Chen, Yee Ling Ng, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 27 October 2023
  9. Pre-treatment 68 Ga-PSMA-11 PET/CT Prognostic Value in Predicting Response to 177Lu-PSMA-I&T Therapy and Patient Survival

    Purpose

    To assess the prognostic value of pre-treatment [ 68 Ga]Ga-PSMA-11 PET/CT and other baseline clinical characteristics in predicting prostate...

    Roya Eisazadeh, Seyed Ali Mirshahvalad, ... Mohsen Beheshti in Molecular Imaging and Biology
    Article Open access 15 February 2024
  10. Prediction of clinically significant prostate cancer by [68 Ga]Ga-PSMA-11 PET/CT: a potential tool for selecting patients for active surveillance

    Purpose

    In our study, our aim was to investigate the role of [ 68 Ga]Ga-PSMA-11 PET /CT imaging in the diagnosis of clinically significant prostate...

    Kaan Akcay, Ali Kibar, ... Levent Kabasakal in European Journal of Nuclear Medicine and Molecular Imaging
    Article 19 December 2023
  11. Evaluating the biodistribution for [68Ga]Ga-PSMA-11 and [18F]F-PSMA-1007 PET/CT with an inter- and intrapatient based analysis

    Background

    Liver uptake in [ 68 Ga]Ga-PSMA-11 PET is used as an internal reference in addition to clinical parameters to select patients for [ 177 Lu]Lu-P...

    Cristina E. Popescu, Boya Zhang, ... Alexander Maurer in EJNMMI Research
    Article Open access 05 April 2024
  12. A prospective head-to-head comparison of [68Ga]Ga-P16-093 and [68Ga]Ga-PSMA-11 PET/CT in patients with primary prostate cancer

    Purpose

    We aimed to compare the diagnostic performance and biodistribution of two similar PET agents, [ 68 Ga]Ga-P16-093 and [ 68 Ga]Ga-PSMA-11, in the...

    Guochang Wang, Linlin Li, ... Zhaohui Zhu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 26 May 2023
  13. Automated segmentation of lesions and organs at risk on [68Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR

    Background

    Prostate-specific membrane antigen (PSMA) PET/CT imaging is widely used for quantitative image analysis, especially in radioligand therapy...

    Elmira Yazdani, Najme Karamzadeh-Ziarati, ... Saeed Reza Kheradpisheh in Cancer Imaging
    Article Open access 29 February 2024
  14. A single-center, multi-factor, retrospective study to improve the diagnostic accuracy of primary prostate cancer using [68Ga]Ga-PSMA-11 total-body PET/CT imaging

    Purpose

    To improve the diagnostic accuracy of initial detection in patients with suspected primary prostate cancer (PCa).

    Methods

    Eighty-four patients...

    **g Lv, Haojun Yu, ... Hongcheng Shi in European Journal of Nuclear Medicine and Molecular Imaging
    Article 09 November 2023
  15. Head-to-head comparison of [68Ga]Ga-PSMA-11 and [18F]FDG PET/CT in multiple myeloma

    Purpose

    The aim of this study was to compare [ 18 F]FDG and [ 68 Ga]Ga-PSMA-11 PET/CT image findings in patients with multiple myeloma (MM).

    ...
    Stephan P. M. Souza, Fernanda C. Frasson, ... Celso D. Ramos in European Journal of Nuclear Medicine and Molecular Imaging
    Article 29 March 2023
  16. Prediction of T staging in PI-RADS 4–5 prostate cancer by combination of multiparametric MRI and 68Ga-PSMA-11 PET/CT

    Background

    In this study, we explored the diagnostic performances of multiparametric magnetic resonance imaging (mpMRI), 68 Ga-PSMA-11 PET/CT and...

    Yuanzhen Ding, Chenghao Mo, ... Hongqian Guo in BMC Urology
    Article Open access 11 December 2023
  17. Total-body PET/CT with half-dose [68 Ga]Ga-PSMA-11 for biochemical recurrent prostate cancer: comparable diagnostic value to short axial field-of-view PET/CT with full-dose [68 Ga]Ga-PSMA-11

    Purpose

    The objective of this study was to evaluate the diagnostic performance and image quality of total-body positron emission tomography/computed...

    Yuheng Liu, Lianghua Li, ... Ruohua Chen in European Journal of Nuclear Medicine and Molecular Imaging
    Article 11 October 2023
  18. Comparison of discovery rates and prognostic utility of [68Ga]Ga-PSMA-11 PET/CT and circulating tumor DNA in prostate cancer—a cross-sectional study

    Background

    Circulating-tumor DNA (ctDNA) and prostate-specific membrane antigen (PSMA) ligand positron-emission tomography (PET) enable...

    Kilian Kluge, Holger Einspieler, ... Alexander Haug in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 02 May 2024
  19. Comparison of parametric imaging and SUV imaging with [68 Ga]Ga-PSMA-11 using dynamic total-body PET/CT in prostate cancer

    Purpose

    Standardized uptake value (SUV) has been prevalently used to measure [ 68 Ga]Ga-PSMA-11 activity in prostate cancer, but it is susceptible to...

    Ruohua Chen, Yee Ling Ng, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging
    Article 04 October 2023
  20. Comparison of quantitative whole body PET parameters on [68Ga]Ga-PSMA-11 PET/CT using ordered Subset Expectation Maximization (OSEM) vs. bayesian penalized likelihood (BPL) reconstruction algorithms in men with metastatic castration-resistant prostate cancer

    Background

    PSMA PET/CT is a predictive and prognostic biomarker for determining response to [ 177 Lu]Lu-PSMA-617 in patients with metastatic castration...

    Narjess Ayati, Lachlan McIntosh, ... Michael S. Hofman in Cancer Imaging
    Article Open access 06 May 2024
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