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GABRB3-related epilepsy: novel variants, clinical features and therapeutic implications
ObjectiveThis study aimed to comprehensively examine the genetic and phenotypic aspects of GABRB3 -related epilepsy and to explore the potential...
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Treatment of Seizures in Older Patients with Dementia
The numbers of patients with dementia and patients with epilepsy are increasing in the global population. In fact, these two conditions are related,...
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Psychogenic Nonepileptic Seizures in Children and Adolescents
ContextThough psychogenic non-epileptic seizures (PNES) are seen commonly during evaluation of children and adolescents with epilepsy, the literature...
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Epileptic seizures in multiple sclerosis: prevalence, competing causes and diagnostic accuracy
BackgroundMultiple sclerosis (MS) is accompanied by an increased risk of epileptic seizures, but data with a detailed description of the competing...
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A different look on the importance of lateralization and localization of figure 4 symptoms in epilepsy
BackgroundClinical seizure semiology provides valuable information in the evaluation of focal-onset bilateral tonic–clonic seizures. In the...
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Effect of Number of Previous Antiseizure Medications on Efficacy and Tolerability of Adjunctive Brivaracetam for Uncontrolled Focal Seizures: Post Hoc Analysis
IntroductionThe aim was to evaluate the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with severely drug-resistant focal...
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Autonomic manifestations of epilepsy: emerging pathways to sudden death?
Epileptic networks are intimately connected with the autonomic nervous system, as exemplified by a plethora of ictal (during a seizure) autonomic...
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Long-term evolution and prognostic factors of epilepsy in limbic encephalitis with LGI1 antibodies
ObjectiveTo characterize the evolution of epilepsy in patients with leucine-rich glioma inactivated 1 antibody-associated (LGI1ab) limbic...
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Clinical characteristics of tuberculous meningitis in older patients compared with younger and middle-aged patients: a retrospective analysis
BackgroundFew studies have analyzed the clinical characteristics and adverse factors affecting prognosis in older patients with tuberculous...
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Predicting factors for acute encephalopathy in febrile seizure children with SARS-CoV-2 omicron variant: a retrospective study
BackgroundSARS-CoV-2 posed a threat to children during the early phase of Omicron wave because many patients presented with febrile seizures. The...
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Treating the symptom or treating the disease in neonatal seizures: a systematic review of the literature
AimThe existing treatment options for neonatal seizures have expanded over the last few decades, but no consensus has been reached regarding the...
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Absence Seizures in Children: Usual and the Unusual
Absence seizures are commonly encountered in clinical practice. The diagnosis is usually straightforward in majority of cases. However, it may be...
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Seizures in posterior reversible encephalopathy syndrome: blood pressure management in normotensive patients
Posterior reversible encephalopathy syndrome (PRES) is a rare clinical disease that refers to the subcortical vasogenic edema involving bilateral...
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Predictors of seizure detection and EEG clinical impact in an italian tertiary emergency department
Background and objectivesEpileptic seizures pose challenges in emergency departments (ED), affecting up to 10% of admitted patients. This study aimed...
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Comparison of Continuous Intracortical and Scalp Electroencephalography in Comatose Patients with Acute Brain Injury
BackgroundDepth electroencephalography (dEEG) is a recent invasive monitoring technique used in patients with acute brain injury. This study aimed to...
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The effect of nocturnal epileptic seizures on cognitive functions in children with idiopathic epilepsy
BackgroundCognitive impairment is a common finding epileptic children. Studies have linked nocturnal epileptic discharges to delayed cognitive...
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A Single- and Multiple-Dose Pharmacokinetic Study of Oral Perampanel in Healthy Chinese Subjects
Background and ObjectivePerampanel is a once-daily oral anti-seizure medication indicated for focal-onset seizures and generalized tonic-clonic...
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The phenotypic spectrum of KCNT1: a new family with variable epilepsy syndromes including mild focal epilepsy
Background and objectivePathogenic variants in KCNT1 have been associated with severe forms of epilepsy, typically sleep-related hypermotor epilepsy...
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Cerebral amyloid angiopathy-related inflammation with posterior reversible encephalopathy syndrome-like presentation: a case report
BackgroundCerebral amyloid angiopathy-related inflammation (CAA-RI), which presents with acute or subacute cognitive or functional decline, focal or...
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Seizures and epilepsy secondary to viral infection in the central nervous system
Viral infection in the central nervous system (CNS) is a common cause of seizures and epilepsy. Acute symptomatic seizures can occur in the context...