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Real-world evidence on treatment pattern, effectiveness, and safety of blinatumomab in Chinese patients with B-cell acute lymphoblastic leukemia
Blinatumomab is efficacious in patients with B-cell acute lymphoblastic leukemia (B-ALL), yet limited real-world data exists in this context. This...
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Factors associated with re-admission in the year after acute postpartum psychiatric treatment
PurposeTo examine factors associated with being re-admitted in the year after discharge from acute postpartum psychiatric treatment.
Methods ... -
Mechanical thrombectomy in patients with heart failure: the Italian registry of Endovascular Treatment in Acute Stroke
BackgroundHeart failure (HF) is the second most important cardiac risk factor for stroke after atrial fibrillation (AF). Few data are available on...
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Venetoclax: A New Partner in the Novel Treatment Era for Acute Myeloid Leukemia and Myelodysplastic Syndrome
BackgroundAcute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) are two closely related blood cancers that are more frequent in older...
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Acute Effects of Coffee Consumption on Blood Pressure and Endothelial Function in Individuals with Hypertension on Antihypertensive Drug Treatment: A Randomized Crossover Trial
IntroductionCoffee is a complex brew that contains several bioactive compounds and some of them can influence blood pressure (BP) and endothelial...
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Diagnosis, treatment, and prevention of severe acute hepatitis of unknown etiology in children
BackgroundSevere acute hepatitis of unknown etiology in children has recently exhibited a global trend of concentrated occurrence. This review aimed...
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Extracellular vesicles in the pathogenesis and treatment of acute lung injury
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-threatening lung diseases associated with acute and severe...
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Treatment challenges and outcomes of older patients with acute myeloid leukemia from India
Globally, overall survival (OS) of older patients with AML continues to be suboptimal with very little data from India. In a multicenter registry...
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Myelomonocytic and monocytic acute myeloid leukemia demonstrate comparable poor outcomes with venetoclax-based treatment: a monocentric real-world study
Venetoclax (VEN), a BCL-2 inhibitor, has transformed treatment strategies for elderly and unfit acute myeloid leukemia (AML) patients by...
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Acute Care Surgery in Geriatric Patients
This comprehensive text will provide a state-of-the art review of the field of geriatric acute care surgery, reviewing new epidemiology data about...
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Exploring Factors Impacting the Implementation of Recovery-Oriented Treatment Planning on Acute Inpatient Mental Health Units
Purpose: The current literature on operationalizing and implementing recovery-oriented inpatient care in diverse settings remains limited. The...
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Acute malnutrition recovery rates improve with COVID-19 adapted nutrition treatment protocols in South Sudan: a mixed methods study
BackgroundGlobally, emergency nutrition program adaptations were implemented as part of COVID-19 mitigation strategies, but the implications of the...
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Association between procedural time and outcome in unsuccessful mechanical thrombectomy for acute ischemic stroke: analysis from the Italian Registry of Endovascular Treatment in Acute Stroke
BackgroundWe aim to assess the association between procedural time and outcomes in patients in unsuccessful mechanical thrombectomy (MT) for anterior...
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Protective Mechanism of Cordyceps sinensis Treatment on Acute Kidney Injury-Induced Acute Lung Injury through AMPK/mTOR Signaling Pathway
ObjectiveTo investigate protective effect of Cordyceps sinensis (CS) through autophagy-associated adenosine monophosphate-activated protein kinase...
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Efficacy of endovascular treatment for completely occlusive acute–subacute portal and mesenteric vein thrombosis with severe complications in patients without cirrhosis
PurposeCompletely occlusive acute–subacute portal and mesenteric vein thrombosis (PVMVT) with severe complications is fatal. Endovascular treatments...
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A comparative study of uncomplicated acute non-A-E hepatitis with acute viral hepatitis and acute onset autoimmune hepatitis
Background and AimsNon-A-E hepatitis (NAEH) not leading to acute liver failure (ALF) is poorly documented. The objective was to compare clinical and...
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Application of metal stent implantation with endoscope and X-ray fluoroscopy combined laparoscopic surgery in the treatment of acute left hemicolon cancer obstruction
BackgroundThis study aimed to conduct a case–control study of endoscopic and fluoroscopic metal stent placement combined with laparoscopic surgery...
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Experiences of treatment decision-making among older newly diagnosed adults with acute myeloid leukemia: a qualitative descriptive study
PurposeTreatment decision-making for older adults with acute myeloid leukemia (AML) is complex and preference-sensitive. We sought to understand the...
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Targeted treatment of T-cell acute lymphoblastic leukemia: latest updates from the 2022 ASH Annual Meeting
T-cell acute lymphoblastic leukemia (T-ALL) occurs in approximately 25–30% of adult ALL. Currently, treatment approaches for adult patients with...
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Older Patients with Acute Myeloid Leukemia Deserve Individualized Treatment
Abstract Purpose of ReviewTreatment of elderly patients with acute myeloid leukemia is a known challenge for hematologists due to patient diversity,...
