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The insula modulates the effects of aerobic training on cardiovascular function and ambulation in multiple sclerosis
BackgroundImpairment of cardiovascular control is common in multiple sclerosis (MS), possibly due to damage of strategic brain regions such as the...
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Altered domain-specific striatal functional connectivity in patients with Parkinson’s disease and urinary symptoms
BackgroundIn this study, we aimed at investigating the possible association of urinary symptoms with whole-brain MRI resting-state functional...
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Functional connectivity changes in neurodegenerative biomarker-positive athletes with repeated concussions
Multimodal biomarkers may identify former contact sports athletes with repeated concussions and at risk for dementia. Our study aims to investigate...
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Involvement of the ipsilateral-to-the-pain anterior–superior hypothalamic subunit in chronic cluster headache
BackgroundDespite hypothalamus has long being considered to be involved in the pathophysiology of cluster headache, the inconsistencies of previous...
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Differential grey matter structure in women with premenstrual dysphoric disorder: evidence from brain morphometry and data-driven classification
Premenstrual dysphoric disorder (PMDD) is a female-specific condition classified in the Diagnostic and Statical Manual—5th edition under depressive...
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Gray and white matter abnormality in patients with T2DM-related cognitive dysfunction: a systemic review and meta-analysis
Aims/hypothesisBrain structure abnormality in patients with type 2 diabetes mellitus (T2DM)-related cognitive dysfunction (T2DM-CD) has been reported...
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Early gray matter atrophy and neurological deficits in patients with carbon monoxide poisoning
PurposeTo investigate early neurological deficits-related change patterns in gray matter (GM) volume in patients with carbon monoxide poisoning (COP)...
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The neural signatures of psychoses in Alzheimer’s disease: a neuroimaging genetics approach
Psychoses in Alzheimer’s disease (AD) are associated with worse prognosis. Genetic vulnerability for schizophrenia (SCZ) may drive AD-related...
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Combined use of gray matter volume and neuropsychological test performance for classification of individuals with bipolar I disorder via artificial neural network method
Diagnosis of patients with bipolar disorder may be challenging and delayed in clinical practice. Neuropsychological impairments and brain...
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Brain structure and cortical activity changes of new daily persistent headache: multimodal evidence from MEG/sMRI
BackgroundNew daily persistent headache (NDPH) is a rare but debilitating primary headache disorder that poses a significant burden on individuals...
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Normal cohorts in automated brain atrophy estimation: how many healthy subjects to include?
ObjectivesThis study investigates the influence of normal cohort (NC) size and the impact of different NCs on automated MRI-based brain atrophy...
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Elucidating the association of obstructive sleep apnea with brain structure and cognitive performance
BackgroundObstructive sleep apnea (OSA) is a pervasive, chronic sleep-related respiratory condition that causes brain structural alterations and...
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Interactive effects of polygenic risk and cognitive subtype on brain morphology in schizophrenia spectrum and bipolar disorders
Grey matter volume (GMV) may be associated with polygenic risk for schizophrenia (PRS-SZ) and severe cognitive deficits in people with schizophrenia,...
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CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease
Post-mortem staging of Alzheimer’s disease (AD) neurofibrillary pathology is commonly performed by immunohistochemistry using AT8 antibody for...
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Cerebellum and cognition in Friedreich ataxia: a voxel-based morphometry and volumetric MRI study
BackgroundRecent studies have suggested the presence of a significant atrophy affecting the cerebellar cortex in Friedreich ataxia (FRDA) patients,...
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Intrinsic brain functional connectivity predicts treatment-related motor complications in early Parkinson’s disease patients
BackgroundTreatment-related motor complications may develop progressively over the course of Parkinson’s disease (PD).
ObjectiveWe investigated...
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Reward motivation adaptation in people with negative schizotypal features: development of a novel behavioural paradigm and identifying its neural correlates using resting-state functional connectivity analysis
Reward motivation in individuals with high levels of negative schizotypal traits (NS) has been found to be lower than that in their counterparts. But...
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Gray matter volume and functional connectivity underlying binge eating in healthy children
PurposeAs a maladaptive disordered eating behavior, binge eating (BE) onset has been reported in children as young as eight years old and is linked...
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Brain morphologic abnormalities in migraine patients: an observational study
BackgroundMigraine is a common neurological disorder characterized by a complex physiopathology. We assessed brain morphologic differences in...
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Volumetric and functional connectivity alterations in patients with chronic cervical spondylotic pain
PurposeTo explore the structural and functional alterations of the whole brain in patients with chronic cervical spondylotic pain (cCSP).
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