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A head-to-head comparison of [68Ga]Ga-DOTATATE and [68Ga]Ga-FAPI PET/CT in patients with nasopharyngeal carcinoma: a single-center, prospective study
PurposeWe aimed to compare the staging efficiency of [ 68 Ga]Ga-DOTATATE and [ 68 Ga]Ga-FAPI PET/CT in nasopharyngeal carcinoma (NPC) patients.
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Current look at the most promising proteomic and glycomic biomarkers of bladder cancer
BackgroundBladder cancer (BC) belongs to the most frequent cancer types. The diagnostic process is still long and costly, with a high percentage of...
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Machine learning prediction models for different stages of non-small cell lung cancer based on tongue and tumor marker: a pilot study
ObjectiveTo analyze the tongue feature of NSCLC at different stages, as well as the correlation between tongue feature and tumor marker, and...
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2-[18F]FDG PET-based quantification of lymph node metabolic heterogeneity for predicting lymph node metastasis in patients with colorectal cancer
Background and purposeThe pre-surgical estimation of lymph node (LN) metastasis in colorectal cancer (CRC) poses a significant diagnostic...
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Individual radiosensitivity reflected by γ-H2AX and 53BP1 foci predicts outcome in PSMA-targeted radioligand therapy
Purposeγ-H2AX and 53BP1 are fundamental for cellular DNA damage response (DDR) after radiation exposure and are linked to cell repair, arrest, or...
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Targeting the epigenome to reinvigorate T cells for cancer immunotherapy
Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) has revolutionized the field of cancer treatment; however, ICI efficacy is constrained...
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High Expression of Bloom Syndrome Helicase is a Key Factor for Poor Prognosis and Advanced Malignancy in Patients with Pancreatic Cancer: A Retrospective Study
BackgroundBloom syndrome helicase (BLM) is overexpressed in multiple types of cancers and its overexpression may induce genomic instability. This...
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Orthohantavirus Infection in Two Rodent Species that Inhabit Wetlands in Argentina
Previous research conducted in central-east region of Argentina recorded potential orthohantavirus host rodents in diverse environments, but no...
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Increased proportions of circulating PD-1+ CD4+ memory T cells and PD-1+ regulatory T cells associate with good response to prednisone in pulmonary sarcoidosis
BackgroundThe treatment response to corticosteroids in patients with sarcoidosis is highly variable. CD4 + T cells are central in sarcoid...
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Meta-analysis of 18 F-PSMA-1007 PET/CT, 18 F-FDG PET/CT, and 68Ga-PSMA PET/CT in diagnostic efficacy of prostate Cancer
ObjectiveTo compare 18 F-PSMA-1007 PET/CT, 18 F-FDG PET/CT and 68 Ga-PSMA PET/CT in the diagnostic value of prostate cancer.
MethodThe Chinese and...
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Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT
BackgroundAs countries move towards or achieve measles elimination status, serosurveillance is an important public health tool. However, a major...
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PathogenTrack and Yeskit: tools for identifying intracellular pathogens from single-cell RNA-sequencing datasets as illustrated by application to COVID-19
Pathogenic microbes can induce cellular dysfunction, immune response, and cause infectious disease and other diseases including cancers. However, the...
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18F-FDG PET/CT based model for predicting malignancy in pulmonary nodules: a meta-analysis
BackgroundSeveral studies to date have reported on the development of positron emission tomography (PET)/computed tomography (CT)-based models...
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Emerging immunotherapeutic strategies for the treatment of breast cancer
Immunotherapy has resulted in unprecedented gains in long-term outcomes for many cancer types and has revolutionized the treatment landscape of solid...
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Human hydatid cyst fluid-induced therapeutic anti-cancer immune responses via NK1.1+ cell activation in mice
Echinococcus granulosus is a cestode parasite which causes cystic echinococcosis disease. Previously we observed that vaccination with E. granulosus ...
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Automatic segmentation of prostate and extracapsular structures in MRI to predict needle deflection in percutaneous prostate intervention
PurposeUnderstanding the three-dimensional anatomy of percutaneous intervention in prostate cancer is essential to avoid complications. Recently,...
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Development and evaluation of a monoclonal antibody-based competitive ELISA for the detection of antibodies against H7 avian influenza virus
BackgroundH7 subtype avian influenza has caused great concern in the global poultry industry and public health. The conventional serological...
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Rapid point-of-care detection of SARS-CoV-2 infection in exhaled breath using ion mobility spectrometry: a pilot study
BackgroundAn effective testing strategy is essential for pandemic control of the novel Coronavirus disease 2019 (COVID-19) caused by infection with...
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Diagnostic accuracy of [18F]PSMA-1007 PET/CT in biochemical recurrence of prostate cancer
AimDespite increasing use for the detection of biochemically recurrent prostate cancer (rPC), the diagnostic accuracy of positron emission...
