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Construction and validation of a risk assessment model for acute kidney injury in patients with acute pancreatitis in the intensive care unit
BackgroundTo construct and validate a risk assessment model for acute kidney injury (AKI) in patients with acute pancreatitis (AP) in the intensive...
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Comprehensive assessment of base excision repair (BER)-related lncRNAs as prognostic and functional biomarkers in lung adenocarcinoma: implications for personalized therapeutics and immunomodulation
BackgroundLung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer, and comprehending its molecular mechanisms is pivotal for...
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Distance-related functional reorganization predicts motor outcome in stroke patients
BackgroundAnalyzing distance-dependent functional connectivity density (FCD) yields valuable insights into patterns of brain activity. Nevertheless,...
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Construction and validation of molecular subtypes of coronary artery disease based on ferroptosis-related genes
BackgroundThis study aims to construct a reliable diagnostic model for coronary artery disease (CAD) patients and explore its potential mechanism by...
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Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis
BackgroundPrimary biliary cholangitis (PBC) is an autoimmune liver disease, whose etiology is yet to be fully elucidated. Currently, ursodeoxycholic...
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Development and validation of the modified index of fragility in head and neck cancer surgery
BackgroundThis study aims to develop and validate, a clinically useful modified index of fragility (mIFG) to identify patients at risk of fragility...
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Survival nomogram for patients with thymic squamous cell carcinoma, based on the SEER database and an external validation cohort
ObjectiveThis study aimed to construct a nomogram to effectively predict the 3 years and 5 years overall survival of patients with thymic squamous...
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Adaption and validation of the Rwandese version of the Young Mania Rating Scale to measure the severity of a manic or hypomanic episode
BackgroundBipolar Disorder is one of the most incapacitating diseases among young persons, leading to cognitive and functional impairment and raised...
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Bronchopulmonary dysplasia: analysis and validation of ferroptosis-related diagnostic biomarkers and immune cell infiltration features
BackgroundEarly and precise diagnosis of bronchopulmonary dysplasia (BPD) is essential to improve the prognosis of preterm infants with BPD. Studying...
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Identification and Validation a Necroptosis-Related Prognostic Signature in Cervical Cancer
Necroptosis is a promising novel target for cervical cancer therapy. Nevertheless, differentially expressed necroptosis-related genes (NRGs) in...
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Measuring context that matters: validation of the modular Tele-QoL patient-reported outcome and experience measure
PurposeA setting-sensitive instrument for assessing Quality of Life (QoL) in Telemedicine (TM) was unavailable. To close this gap, a content-valid...
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Longitudinal inference of multiscale markers in psychosis: from hippocampal centrality to functional outcome
Multiscale neuroscience conceptualizes mental illness as arising from aberrant interactions across and within multiple biopsychosocial scales. We...
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Converting between the International Prostate Symptom Score (IPSS) and the Expanded Prostate Cancer Index Composite (EPIC) urinary subscales: modeling and external validation
BackgroundProstate-related quality of life can be assessed with a variety of different questionnaires. The 50-item Expanded Prostate Cancer Index...
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Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencing
BackgroundThe exact mechanisms of type 2 diabetes mellitus (T2DM) remain largely unknown. We intended to authenticate critical genes linked to T2DM...
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Development and Validation of a Questionnaire to Assess the Effect of Vestibular Rehabilitation Therapy
Vestibular rehabilitation therapy (VRT) is an effective treatment for individuals experiencing imbalance and dizziness, helps to improve the quality...
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Constructing a prognostic model for colorectal cancer with synchronous liver metastases after preoperative chemotherapy: a study based on SEER and an external validation cohort
BackgroundThe combination of preoperative chemotherapy and surgical treatment has been shown to significantly enhance the prognosis of colorectal...
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Resting state functional brain connectivity in child and adolescent psychiatry: where are we now?
Approaching the 30th anniversary of the discovery of resting state functional magnetic resonance imaging (rsfMRI) functional connectivity, we reflect...
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Physical activity and functional social support in community-dwelling older adults: a sco** review
BackgroundGlobally, the population of older people is increasing and is estimated to reach nearly 2.1 billion by 2050. Physical activity (PA) is one...
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Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
Cuprotosis is a novel and unique form of cell death that is of great value in a variety of cancers. However, the prognostic role of...
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Validation of a fall rate prediction model for community-dwelling older adults: a combined analysis of three cohorts with 1850 participants
BackgroundFragility fractures in older adults are often caused by fall events. The estimation of an expected fall rate might improve the...
