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Post-marketing surveillance of the safety and effectiveness of nivolumab for classic Hodgkin lymphoma in Japan
Nivolumab was approved for relapsed/refractory classic Hodgkin lymphoma (cHL) in Japan in 2016. After its approval, a prospective,...
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Cost-effectiveness of weight-management pharmacotherapies in Canada: a societal perspective
ObjectivesThis study aimed to assess the cost-effectiveness of weight-management pharmacotherapies approved by Canada Health, i.e., orlistat,...
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A cost-effectiveness evaluation of a dietitian-delivered telephone coaching program during pregnancy for preventing gestational diabetes mellitus
BackgroundThis study aimed to evaluate the cost-effectiveness of a telehealth coaching intervention to prevent gestational diabetes mellitus (GDM)...
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Lipid-Lowering Strategies for Primary Prevention of Coronary Heart Disease in the UK: A Cost-Effectiveness Analysis
AimWe aimed to assess the cost effectiveness of four different lipid-lowering strategies for primary prevention of coronary heart disease initiated...
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Cost-effectiveness of WEB Embolization, Coiling and Stent-assisted Coiling for the Treatment of Unruptured Intracranial Aneurysms
PurposeInformation about the cost-effectiveness of a certain treatment is relevant for decision-making and healthcare providers. This study compares...
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Tranexamic acid for the prevention of postpartum hemorrhage: a cost-effectiveness analysis
Postpartum hemorrhage is a significant contributor to maternal mortality worldwide and in the United States. Tranexamic acid (TXA) has been shown to...
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Effectiveness of atopic dermatitis patient education programs – a systematic review and meta-analysis
Patient education in atopic dermatitis (AD) has worked in parallel to the gold standard of pharmacological treatment as a foundational component of...
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The effectiveness and pharmacoeconomic study of using different corticosteroids in the treatment of hypersensitivity pneumonitis
PurposeInterstitial lung diseases (ILDs) are caused by inflammation and/or fibrosis of alveolar walls resulting in impaired gas exchange....
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Impact of polygenic score for BMI on weight loss effectiveness and genome-wide association analysis
BackgroundWhile environmental factors play an important role in weight loss effectiveness, genetics may also influence its success. We examined...
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The Effectiveness of Screening Total Colonoscopy for Preoperative Patients with Gastric Cancer
BackgroundColorectal cancer (CRC) is the most common cancer that coincides with gastric cancer (GC). Although the usefulness of total colonoscopy...
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Cost-effectiveness of endovascular treatment for acute ischemic stroke in China: evidence from Shandong Peninsula
BackgroundRecently, the endovascular treatment (EVT) of acute ischemic stroke has made significant progress in many aspects. Intravenous thrombolysis...
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Protocol to evaluate the effectiveness and cost-effectiveness of an environmental nutrition and physical activity intervention in nurseries (Nutrition and Physical Activity Self Assessment for Child Care - NAP SACC UK): a multicentre cluster randomised controlled trial
BackgroundOne in seven UK children have obesity when starting school, with higher prevalence associated with deprivation. Most pre-school children do...
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Cost-effectiveness of toripalimab plus chemotherapy for advanced esophageal squamous cell carcinoma
BackgroundToripalimab is an immune checkpoint inhibitor (ICI) against programmed death ligand 1 (PD-L1). It has been approved for advanced esophageal...
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DépistaFest: The evaluation of an inclusive, positive, and playful STBBI screening campaign’s effectiveness
ObjectivesYoung adults are disproportionately affected by sexually transmitted and blood-borne infections (STBBIs), and rates of STBBI screening in...
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Assessing the effectiveness and cost-effectiveness of a solution-focused resource-orientated approach (DIALOG+) to improving the quality of life for people with psychosis in India and Pakistan—a cluster RCT
BackgroundSevere mental illness (SMI) presents a major challenge worldwide, affecting approximately 5–8% of the world’s population. It causes...
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Improving the efficacy and effectiveness of evidence-based psychosocial interventions for attention-deficit/hyperactivity disorder (ADHD) in children and adolescents
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent, chronic, and impairing mental health disorder of childhood. Decades of empirical...
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Determinant factors for first-line treatment choice and effectiveness in pediatric eosinophilic esophagitis: an analysis of the EUREOS EoE CONNECT registry
This study compared short-term effectiveness of proton pump inhibitors (PPI), swallowed topical corticosteroids (STC), and dietary therapies in...
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Cost-effectiveness of prehabilitation prior to elective surgery: a systematic review of economic evaluations
BackgroundPrehabilitation aims at enhancing patients’ functional capacity and overall health status to enable them to withstand a forthcoming...
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Cost-effectiveness of pembrolizumab versus chemotherapy in patients with platinum-pretreated, recurrent or metastatic nasopharyngeal cancer
BackgroundProgrammed cell death protein 1 (PD-1) monoclonal antibody, pembrolizumab, is a promising drug for platinum-pretreated, recurrent or...
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Cost-effectiveness of on-demand removal of syndesmotic screws
PurposeSyndesmotic screw removal following acute syndesmotic injury is a commonly performed procedure. However, recent studies suggest that the...