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Concordance of skin test reactivity between indoor inhalant allergens among children with allergic respiratory disease
BackgroundIn vitro studies have demonstrated cross-reactivity among indoor allergen proteins in children with allergic respiratory diseases. However,...
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Clinical genetic testing in four highly suspected pediatric restrictive cardiomyopathy cases
BackgroundRestrictive cardiomyopathy (RCM) presents a high risk for sudden cardiac death in pediatric patients. Constrictive pericarditis (CP)...
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Comparisons of the protein expressions between high myopia and moderate myopia on the anterior corneal stroma in human
PurposeTo investigate the differentially expressed proteins (DEP) between high myopia and moderate myopia on the anterior corneal stroma.
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Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression
BackgroundDepression is a severe neuropsychiatric disorder that affects more than 264 million people worldwide. The efficacy of conventional...
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Tropomyosin Receptor Kinase B Agonist, 7,8-Dihydroxyflavone, Improves Mitochondrial Respiration in Placentas From Obese Women
Maternal obesity negatively impacts the placenta, being associated with increased inflammation, decreased mitochondrial respiration, decreased...
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Targeting metaplasticity mechanisms to promote sustained antidepressant actions
The discovery that subanesthetic doses of (R, S)-ketamine (ketamine) and (S)-ketamine (esketamine) rapidly induce antidepressant effects and promote...
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Dilated cardiomyopathy due to hypocalcaemia: a case report
BackgroundHypocalcaemia is a rare, but reversible, cause of dilated cardiomyopathy causing heart failure. Several case reports have been reported on...
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Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro
BackgroundIn-vitro-grow (IVG) of preantral follicles is essential for female fertility preservation, while practical approach for improvement is far...
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Assessment of TSLP, IL 25 and IL 33 in patients with shrimp allergy
BackgroundShrimp allergy is a growing problem among the European population. TSLP, IL-25 and IL-33 are involved in the pathophysiology of allergic...
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Genetic predisposition study of heart failure and its association with cardiomyopathy
Heart failure (HF) is a clinical condition distinguished by structural and functional defects in the myocardium, which genetic and environmental...
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Innovation in Targeted Intra-articular Therapies for Osteoarthritis
Osteoarthritis is the most common chronic joint disease characterized by progressive damage to the joints, leading to pain and loss of function....
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Dilatative fetal cardiomyopathy followed by a mirror syndrome
Mirror syndrome (Ballantyne syndrome) is a rare condition characterized by maternal edema, which often affects the lungs. It mirrors the image of...
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Neurotrophic factors-based therapeutic strategies in the spinal cord injury: an overview of recent preclinical studies in rodent models
Following the traumatic spinal cord injury (SCI) and initial mechanical insult, a cascade of secondary cellular and molecular events occurs at the...
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Exploring the potential of vagus nerve stimulation in treating brain diseases: a review of immunologic benefits and neuroprotective efficacy
The vagus nerve serves as a critical connection between the central nervous system and internal organs. Originally known for its effectiveness in...
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NTRK-rearranged spindle cell sarcoma of the uterine cervix with a novel NUMA1::NTRK1 fusion
NTRK -rearranged uterine sarcoma is a recently described entity that represents a subset of uterine sarcomas with distinct clinicopathological...
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Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth
BackgroundPreterm birth is defined as live birth before 37 completed weeks of pregnancy, and it is a major problem worldwide. The molecular...
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Long-term evaluation of safety and biological effects of Korean Red Ginseng (Panax Ginseng): a long-term in vivo study
BackgroundAlthough Korean Red Ginseng (KRG) is safe, this finding was only evaluated in 3-mo-long studies. Its safety was verified through a 6-mo KRG...
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Striatal Shati/Nat8l–BDNF pathways determine the sensitivity to social defeat stress in mice through epigenetic regulation
The global number of patients with depression increases in correlation to exposure to social stress. Chronic stress does not trigger depression in...
