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Fatigue after spontaneous intracerebral haemorrhage: prevalence and associated factors
BackgroundFatigue is a major complaint in stroke survivors, but data focusing on intracerebral haemorrhage (ICH) survivors are scarce. In a cohort of...
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Spontaneous thrombosis of vein of Galen malformation managed with surgical resection: a case‑based review
IntroductionVein of Galen malformation (VOGM) is an exceptionally uncommon form of congenital intracranial vascular malformations. It is highly...
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Spontaneous urinary bladder perforation presenting as bowel obstruction in a child: a case report
BackgroundSpontaneous perforation of the urinary bladder is a rare disease entity. Due to its rarity, it is often hard to diagnose.
Case presentation ...
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Spontaneous Retroperitoneal Haemorrhage: Efficacy of Conservative Management and Embolisation
PurposeTo assess the efficacy of conservative management and embolisation in patients with spontaneous retroperitoneal haemorrhage.
Methods ...
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New medicines for spontaneous preterm birth prevention and preterm labour management: landscape analysis of the medicine development pipeline
BackgroundThere are few medicines in clinical use for managing preterm labor or preventing spontaneous preterm birth from occurring. We previously...
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Chronic Spontaneous Urticaria: How to Measure It and the Need to Define Treatment Success
Chronic spontaneous urticaria (CSU) is a complex skin disease characterized by the spontaneous appearance of wheals, angioedema, or both, for more...
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Necrotizing enterocolitis in a term newborn after spontaneous cerebral parenchymal hemorrhage: a case report
BackgroundNecrotizing enterocolitis (NEC) and intracranial hemorrhage are severe emergencies in the neonatal period. The two do not appear to be...
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Spontaneous skull base cerebrospinal fluid leak during pregnancy: a case report and review of the literature
BackgroundIdiopathic intracranial hypertension can lead to dural defects and spontaneous leakage of cerebrospinal fluid (CSF) from the skull base....
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Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection
Spontaneous reactivation of the Hepatitis B virus (HBV) is rare in individuals with previously resolved infections. This report presents the case of...
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Current and Emerging Therapies for Chronic Spontaneous Urticaria: A Narrative Review
Chronic spontaneous urticaria (CSU) is a condition in which wheals, angioedema, and pruritus occur spontaneously and recurrently for at least...
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Spontaneous regression in solid pseudopapillary neoplasm of pancreas
A solid pseudopapillary neoplasm (SPN) of the pancreas is a rare neoplasm that mainly occurs in young women. We herein report the case of spontaneous...
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Spontaneous expression of the CIC::DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice
CIC::DUX4 sarcoma (CDS) is a rare but highly aggressive undifferentiated small round cell sarcoma driven by a fusion between the tumor suppressor...
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Spontaneous Development and Resolution of Cervical Epidural Haematoma: a Case Report
Spontaneous cervical epidural haematoma (CEH) is a rare neurologic emergency that can lead to catastrophic and irreversible neurological deficits....
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Spontaneous regression of advanced transverse colon cancer with deficient mismatch repair: a case report
BackgroundSpontaneous regression (SR) of cancer occurs in 1 in 60,000–100,000 patients. This phenomenon has been reported in almost all cancer types,...
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Phenomenology of spontaneous closure in degenerative and mixed type lamellar macular hole
PurposeTo the describe OCT imaging characteristics of a cohort of patients showing spontaneously closing degenerative or mixed type lamellar macular...
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Spontaneous pneumoperitoneum in neonates: a case series
BackgroundPneumoperitoneum is defined as the presence of free air in the peritoneal cavity. It is a surgical emergency that represents in 90% of the...
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Spontaneous cerebrospinal fluid fistula secondary to hyper-pneumatized paranasal sinuses and skull base: two case reports
BackgroundSpontaneous cerebrospinal fluid (CSF) fistulas occur due to various reasons other than well-identified causes such as trauma, neoplasia or...
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Spontaneous Bone Neo-formation After Mandibular Resection: Case Report and a Sco** Review
BackgroundMandibular tumors in children are mostly benign, although they can be locally aggressive and rapidly progressing. Methods of reconstructing...
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Congenital lower urinary tract obstruction with spontaneous fetal bladder rupture due to posterior urethral valves: a case report
BackgroundCongenital lower urinary tract obstruction (LUTO) is a rare but significant condition affecting fetal urinary tract development. LUTO has a...
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Anti-β2-glycoprotein I antibody maybe a novel biomarker of spontaneous preterm birth
BackgroundSpontaneous preterm birth is challenging to prevent. Only few predictors of spontaneous preterm birth risk have been reported, and further...
