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Managing fluid balance and nutritional status in a short bowel syndrome patient awaiting intestinal transplant: a case report
BackgroundDespite being a long-term therapy for patients with short bowel syndrome (SBS), subcutaneous injections of teduglutide promote the...
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Photodynamic therapy in oral cancer: a review of clinical studies
A significant mortality rate is associated with oral cancer, particularly in cases of late-stage diagnosis. Since the last decades, oral cancer...
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Rational use of Volume Replacement Fluids in Patients of Oral and Maxillofacial Surgery
IntroductionFluid resuscitation is fundamental for the management of general trauma, hemorrhagic shock, and generalized infections. The aim of this...
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The effects of fluid absorption and plasma volume changes in athletes following consumption of various beverages
BackgroundTo verify the hydration effects of oral rehydration solution (ORS) on athletes by comparing the degrees of fluid absorption and plasma...
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Evolutionary bridges: how factors present in amniotic fluid and human milk help mature the gut
Necrotizing enterocolitis (NEC) continues to be a leading cause of morbidity and mortality in preterm infants. As modern medicine significantly...
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The role of the oral microbiome in obesity and metabolic disease: potential systemic implications and effects on taste perception
Obesity and its metabolic sequelae still comprise a challenge when it comes to understanding mechanisms, which drive these pandemic diseases. The...
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Current use of fluid biomarkers as outcome measures in Multiple Sclerosis (MS): a review of ongoing pharmacological clinical trials
The present study aims to describe the state of the art of fluid biomarkers use in ongoing multiple sclerosis (MS) clinical trials.
A review of 608...
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The Association of Oral Microbiome Dysbiosis with Gastrointestinal Cancers and Its Diagnostic Efficacy
BackgroundThe second leading mortality cause in the world is cancer, making it a critical issue that impacts human health. As a result, scientists...
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Oral phage therapy with microencapsulated phage A221 against Escherichia coli infections in weaned piglets
BackgroundEscherichia coli (E. coli) is a common pathogen that often causes diarrhea in piglets. Since bacteria are becoming more and more resistant...
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Comparing the Clinical and Microbiological Effects of Antibacterial-Coated Vicryl Suture and Non-Coated Vicryl Suture after Minor Oral Surgical Procedures
Background and ObjectiveSurgical site infections are among the most common nosocomial infections, potentially leading to serious complications after...
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Considering the Oral Bioavailability of Protein Kinase Inhibitors: Essential in Assessing the Extent of Drug–Drug Interaction and Improving Clinical Practice
Protein kinase inhibitors share pharmacokinetic (PK) pathways among themselves. They are all metabolized by several cytochromes P450 (CYP). For most...
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Cytomegalovirus lumbosacral polyradiculitis in patients with long-term use of an oral corticosteroid: a case report
BackgroundThe long-term use of an oral corticosteroid suppresses immunity. Here, we describe a case involving a patient with weakness in the...
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Optimal Perioperative Fluid Therapy Associates with Fewer Complications After Pancreaticoduodenectomy
BackgroundOptimal fluid management in pancreaticoduodenectomy patients remains contested. We aimed to examine the association between perioperative...
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Prospective longitudinal analysis of clinical and immunological risk factors associated with oral and gastrointestinal mucositis following autologous stem cell transplant in adults
PurposeThe study aimed to characterize the incidence of both oral and gastrointestinal (GI) mucositis, its’ associated temporal changes in local and...
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Snoring-generated fluid droplets as a potential mechanistic link between sleep-disordered breathing and pneumonia
The soft palate and back of the throat represent vulnerable early infection sites for SARS-CoV-2, influenza, streptococci, and many other pathogens....
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Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer’s Disease
IntroductionALZ-801/valiltramiprosate is a small-molecule oral inhibitor of beta amyloid (Aβ) aggregation and oligomer formation being studied in a...
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Acceptability of the Dapivirine Vaginal Ring and Oral Truvada Among African Users in Late-Stage of Pregnancy
The Microbicide Trials Network 042 study (MTN-042/DELIVER) is a two-arm, randomized, open-label Phase 3b trial that is evaluating the safety,...
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P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway
BackgroundBenign prostatic hyperplasia (BPH) is the most common disease in elderly men. There is increasing evidence that periodontitis increases the...