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Si-Wu-Tang alleviates metabolic dysfunction-associated fatty liver disease by inhibiting ACSL4-mediated arachidonic acid metabolism and ferroptosis in MCD diet-fed mice
BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) is a prevalent chronic liver disease worldwide. Si-Wu-Tang (SWT), a...
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Microvesicular Steatosis in Individuals with Obesity: a Histological Marker of Non-alcoholic Fatty Liver Disease Severity
BackgroundIn non-alcoholic fatty liver disease (NAFLD), steatosis can manifest through two distinct forms: macrovesicular (macroS) and microvesicular...
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Visualizing lipid behind the retina in aging and age-related macular degeneration, via indocyanine green angiography (ASHS-LIA)
Age-related macular degeneration (AMD) causes legal blindness in older adults worldwide. Soft drusen are the most extensively documented intraocular...
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Comparison of strain elastography and shear wave elastography in diagnosis of fibrosis in nonalcoholic fatty liver disease
PurposeTo reveal the ability of S-Map strain elastography to diagnose fibrosis in nonalcoholic fatty liver disease (NAFLD) and to compare its...
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Outcomes after laparoscopic or open liver resection for nonalcoholic fatty liver disease-associated hepatocellular carcinoma: a propensity score-matching study
BackgroundLaparoscopic liver resection (LLR) is rapidly gaining popularity; however, its efficacy for nonalcoholic fatty liver disease...
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Cumulative exposure to AHA Life's Essential 8 is associated with nonalcoholic fatty liver disease: a large cohort study
Background and AimWe aimed to explore the associations of baseline and cumulative cardiovascular health with nonalcoholic fatty liver disease (NAFLD)...
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Evaluation of nutritional status of the individuals with age-related macular degeneration (AMD)
PurposeThis study aimed to examine the anthropometric measurements and nutritional status of individuals with age-related macular degeneration (AMD)...
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Could the tendon degeneration and the fatty infiltration of the gluteus medius affect clinical outcome in total hip arthroplasty?
PurposeThe aim of this prospective study was to perform a clinical and radiologic evaluation of patients undergoing total hip arthroplasty (THA). The...
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Excess fatty acids induce pancreatic acinar cell pyroptosis through macrophage M1 polarization
Free fatty acid derived from hyperlipidemia contributes to the development of inflammation in the pancreas. Here we explore the molecular mechanisms...
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Comparative study of ultrasound attenuation analysis and controlled attenuation parameter in the diagnosis and grading of liver steatosis in non-alcoholic fatty liver disease patients
PurposeTo assess the diagnostic performance of Ultrasound Attenuation Analysis (USAT) in the diagnosis and grading of hepatic steatosis in patients...
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Correlation between multifidus fatty atrophy and lumbar disc degeneration in low back pain
BackgroundChronic low back pain (LBP) is common and associated with lumbar disc herniation. The purpose of this study was to investigate if the grade...
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Ultrasound shear wave elastography-derived tissue stiffness is positively correlated with rotator cuff tear size and muscular degeneration
PurposeThe purpose of this study is to describe rotator cuff muscle stiffness in patients with different degrees of rotator cuff tear (RCT) severity...
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Shear wave elastography in evaluation of carotid elasticity in the type 2 diabetes mellitus patients with nonalcoholic fatty liver disease
PurposeUsing shear wave elastography (SWE) to assess carotid elasticity in the type 2 diabetes mellitus (T2DM) patients with non-alcoholic fatty...
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Water extract from artichoke ameliorates high-fat diet-induced non-alcoholic fatty liver disease in rats
BackgroundThe “multiple-hit” hypothesis is currently the most widely accepted theory for non-alcoholic fatty liver disease (NAFLD) pathogenesis. The...
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Polygenic risk score and biochemical/environmental variables predict a low-risk profile of age-related macular degeneration in Sardinia
PurposeTo ascertain the prevalence and clinical and genetic features of age-related macular degeneration (AMD) in subjects living in the Lanusei...
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Correlation between nonalcoholic fatty liver disease and left ventricular diastolic dysfunction in non-obese adults: a cross-sectional study
Background and aimsNon-alcoholic fatty liver disease (NAFLD) is associated with a greater risk of develo** cardiovascular disease and have adverse...
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Erector spinae could be the game changer in surgical decision-making in patients with lumbar spondylolisthesis: a cross-sectional analysis of an age-, sex-, subtype-, level-matched patients with similar spinopelvic parameters received surgical or conservative management
PurposeIn this study we aimed to identify whether paraspinal muscle morphology could play a role in surgical decision-making in patients with lumbar...
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Relationship between oseteoporosis with fatty infiltration of paraspinal muscles based on QCT examination
IntroductionTo investigate the correlation between paraspinal muscles features and osteoporosis in lumbar spine.
Materials and methods ...
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Metabolic associated fatty liver disease and bone mineral density: a cross-sectional study of the National Health and Nutrition Examination Survey 2017–2018
SummaryThis research is a cross-sectional study based on the participants aged 50 years and older from National Health and Nutrition Examination...
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Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading cause of liver disease worldwide. NASH, an advanced form of...
