Search
Search Results
-
Capsaicin alleviates neuronal apoptosis and schizophrenia-like behavioral abnormalities induced by early life stress
Early life stress (ELS) is associated with the later development of schizophrenia. In the rodent model, the maternal separation (MS) stress may...
-
Diagnostic Challenges of Coccidioidomycosis in Solid Organ and Hematopoietic Stem Cell Transplant Recipients
Purpose of ReviewThe goal of our manuscript is to address the diagnostic challenges in coccidioidomycosis related infections among solid organ...
-
A novel EIF3C-related CD8+ T-cell signature in predicting prognosis and immunotherapy response of nasopharyngeal carcinoma
PurposeAt present, dysfunctional CD8 + T-cells in the nasopharyngeal carcinoma (NPC) tumor immune microenvironment (TIME) have caused unsatisfactory...
-
Single-cell RNA sequencing to identify cellular heterogeneity and targets in cardiovascular diseases: from bench to bedside
The mechanisms of cardiovascular diseases (CVDs) remain incompletely elucidated. Single-cell RNA sequencing (scRNA-seq) has enabled the profiling of...
-
Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes
BackgroundLow back pain is a leading cause of disability worldwide and is frequently attributed to intervertebral disc (IVD) degeneration. Though the...
-
Association of carotid atherosclerotic plaque and intima-media thickness with the monocyte to high-density lipoprotein cholesterol ratio among low-income residents of rural China: a population-based cross-sectional study
BackgroundThe monocytes to high-density lipoprotein cholesterol ratio (MHR) has been identified as a potential biomarker for cardiovascular and...
-
Pathogen spectrum of community acquired pneumonia in people living with HIV (PLWH) in the German CAPNETZ-Cohort
ObjectivesThe objective of this study was to identify the pathogen spectrum of community acquired pneumonia in people living with HIV (PLWH), and to...
-
Risk factors and predicting nomogram for the clinical deterioration of non-severe community-acquired pneumonia
BackgroundCurrently, there remains insufficient focus on non-severe community-acquired pneumonia (CAP) patients who are at risk of clinical...
-
Development and validation of a survival prediction model in elder patients with community-acquired pneumonia: a MIMIC-population-based study
BackgroundTo develop a prediction model predicting in-hospital mortality of elder patients with community-acquired pneumonia (CAP) admitted to the...
-
Host genetic variants associated with susceptibility and severity of pneumococcal pneumonia in adult patients
BackgroundPneumococcal community-acquired pneumonia (P-CAP) is a major cause of morbidity and hospitalization. Several host genetics factors...
-
Sequencing of Novel Therapies for Mantle Cell Lymphoma
There is no standard approach to sequencing novel therapies in mantle cell lymphoma (MCL). For initial treatment, intensive induction chemotherapy...
-
CapG promoted nasopharyngeal carcinoma cell motility involving Rho motility pathway independent of ROCK
BackgroundGelsolin-like cap** actin protein (CapG) modulates actin dynamics and actin-based motility with a debatable role in tumorigenic...
-
Early Detection of Aspergillus Species in Lower Respiratory Tract is Associated with Higher Mortality in Viral Community-Acquired Pneumonia: A Multicenter Prospective Cohort Study in China
PurposeCommunity-acquired pneumonia (CAP) is a leading cause of adult mortality worldwide and poses a significant global burden. Previous studies...
-
MRI of squamous cell carcinoma of the nail apparatus: report of 6 cases
Malignant tumors of the nail apparatus are rare and dominated by squamous cell carcinomas (SCC). Routinely, their pre-therapy imaging is limited to...
-
The relationship between frailty and community-acquired pneumonia in older patients
PurposesTo explore the relationship between frailty and community-acquired pneumonia (CAP) in older patients.
MethodsA prospective observational...
-
Expanding the phenotypic spectrum of LHCGR signal peptide insertion variant: novel clinical and allelic findings causing Leydig cell hypoplasia type II
PurposeLeydig cell hypoplasia (LCH) type II is a rare disease with only a few cases reported. Patients presented with hypospadias, micropenis,...
-
Deep learning-based image annotation for leukocyte segmentation and classification of blood cell morphology
The research focuses on the segmentation and classification of leukocytes, a crucial task in medical image analysis for diagnosing various diseases....
-
Comparison of systemic inflammatory profiles in COVID-19 and community-acquired pneumonia patients: a prospective cohort study
BackgroundInflammatory responses contribute to tissue damage in COVID-19 and community-acquired pneumonia (CAP). Although predictive values of...
-
The etiological diagnostic value of metagenomic next-generation sequencing in suspected community-acquired pneumonia
BackgroundThe emergence of metagenomic next-generation sequencing (mNGS) may provide a promising tool for early and comprehensive identification of...
