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Inhalation of smoke from burning tire triggers oxidative stress and impairs liver and kidney functions in rats
In Nigeria, abattoir workers use scrap tires as a source of fuel to remove furs from slaughtered animals. The smoke from the tires contains...
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Amino acid metabolism in health and disease
Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth,...
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Effects of Ibuprofen on Muscle Hypertrophy and Inflammation: a Review of Literature
Purpose of ReviewNon-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for post-exercise recovery and reduction of muscle soreness and...
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Study of serum calcium and phosphorus levels in chronic kidney disease patients with acute coronary syndrome
BackgroundCardiovascular (CVS) conditions remain the main etiology of death in individuals with chronic kidney disease (CKD) even after control of...
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The association between Helicobacter pylori infection and the risk for gout in hyperuricemia patients in China – A cross-sectional study
PurposeHelicobacter pylori ( H. pylori ) infection has been reported to be associated with multiple metabolic diseases. However, the connection...
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A metabolically stable PET tracer for imaging synaptic vesicle protein 2A: synthesis and preclinical characterization of [18F]SDM-16
PurposeTo quantify the synaptic vesicle glycoprotein 2A (SV2A) changes in the whole central nervous system (CNS) under pathophysiological conditions,...
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The association between plasma free amino acids and type 2 diabetes mellitus complicated with infection in Chinese patients
BackgroundType 2 diabetes mellitus (T2DM), one of the most common public diseases threatening human health, is always accompanied by infection....
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Synthesis, radiolabeling, and pre-clinical evaluation of [44Sc]Sc-AAZTA conjugate PSMA inhibitor, a new tracer for high-efficiency imaging of prostate cancer
PurposeThe aim of this work was to demonstrate the suitability of AAZTA conjugated to PSMA inhibitor (B28110) labeled with scandium-44 as a new PET...
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Evaluation of haematological and biochemical changes following xylazine, tramadol and lignocaine premedicated propofol anaesthesia in West African dwarf goat
Diseases are the major factors that cause alteration in both haematologic and biochemical profile of the animal. Some anaesthetic drugs also alter...
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Acute kidney injury in patients with primary nephrotic syndrome: influencing factors and co** strategies
BackgroundAcute kidney injury (AKI) is a frequent and serious complication in patients with primary nephrotic syndrome (PNS). We aimed to evaluate...
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What Do Higher Alanine Aminotransferase Levels Mean in Premature Ovarian Insufficiency?
The objective of this study was to investigate the relationship between alanine aminotransferase and related biochemical parameters and potential...
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The therapeutic potential of “Crataegus azarolus” on zinc, lipid profile, and antioxidant status in streptozotocin-induced diabetic rats with zinc-deficient diet
Zinc plays an important role in the biosynthesis and storage of insulin. Consequently, its deficiency may have a deleterious impact on the...
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Blood pressure and nitric oxide synthesis capacity in physically active and inactive groups: the SABPA study
Physical activity affects the vasculature through mechanisms related to nitric oxide bioavailability, oxidative stress, and inflammation; with...
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Modulatory effect of PPAR-γ by acetate on cardiorenometabolic disturbance associated with high fat diet–fed insulin-resistant male Wistar rats
Insulin resistance (IR) is a critical pathogenic factor for cardiovascular disease (CVD) and chronic kidney disease (CKD). These two diseases...
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Dryopteris dilatata leaf extract ameliorates streptozotocin-induced diabetic nephropathy in male Wistar rat
BackgroundDiabetic nephropathy (DN) is a serious consequence of diabetes mellitus (DM), and it is linked to higher morbidity and mortality in...
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Chestnut tannin extract modulates growth performance and fatty acid composition in finishing Tan lambs by regulating blood antioxidant capacity, rumen fermentation, and biohydrogenation
Tannins as plant extracts have emerged as promising and potential alternatives for antibiotics in modern livestock cultivation systems. This study...
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In vivo stable 211At-labeled prostate-specific membrane antigen-targeted tracer using a neopentyl glycol structure
BackgroundProstate cancer is a common cancer among men worldwide that has a very poor prognosis, especially when it progresses to metastatic...
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Albumin infusion may decrease the mortality of hypoalbuminemia patients with severe acute pancreatitis: a retrospective cohort study
BackgroundAt present, the relationship between severe acute pancreatitis (SAP) and albumin infusion is not clear. We aimed to identify the impact of...
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Astragalus polysaccharide attenuates diabetic nephropathy by reducing apoptosis and enhancing autophagy through activation of Sirt1/FoxO1 pathway
ObjectiveDiabetic nephropathy (DN) is the leading cause of end-stage renal disease in diabetic patients. Astragalus polysaccharide (APS) is a natural...
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Effects of corn supplementation on meat quality and fatty acid composition of Dorper lambs fed PKC-Urea treated rice straw
BackgroundThe increasing costs of feed has subsequently increased the costs of production of livestock, thereby decreasing the profit margin of this...