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The value of FDG PET/CT imaging in outcome prediction and response assessment of lymphoma patients treated with immunotherapy: a meta-analysis and systematic review
PurposeTreatment strategies of lymphoid malignancies have been revolutionized by immunotherapy. Because of the inherent property of Hodgkin lymphoma...
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Muscle-invasive bladder cancer: pretreatment prediction of response to neoadjuvant chemotherapy with diffusion-weighted MR imaging
PurposeTo investigate the usefulness of diffusion-weighted MR imaging with ADC value and histogram analysis of ADC in the prediction of response to...
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[89Zr]-immuno-PET prediction of response to rituximab treatment in patients with therapy refractory interstitial pneumonitis: a phase 2 trial
IntroductionImmune-mediated interstitial pneumonitis may be treated with anti-CD20 therapy after failure of conventional therapies. However, clinical...
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Evaluating the prediction power and accuracy of two smart response surface experimental designs after revisiting repaglinide floating tablets
BackgroundThere is a soar in the figure of companies aiming to achieve efficiency in undergoing experimental processes. Therefore, instead of...
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Endorectal ultrasound radiomics in locally advanced rectal cancer patients: despeckling and radiotherapy response prediction using machine learning
PurposeThe current study aimed to evaluate the association of endorectal ultrasound (EUS) radiomics features at different denoising filters based on...
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Predicting the ovarian response: towards a determinant model and implications for practice
ObjectiveTo improve the reliability of prediction models for ovarian response to stimulation in ART.
DesignA multicenter retrospective cohort study.
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Prediction of influenza outbreaks in Fuzhou, China: comparative analysis of forecasting models
BackgroundInfluenza is a highly contagious respiratory disease that presents a significant challenge to public health globally. Therefore, effective...
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Computed tomography-based deep-learning prediction of induction chemotherapy treatment response in locally advanced nasopharyngeal carcinoma
BackgroundDeep learning methods have great potential to predict treatment response. The objective of this study was to evaluate and validate the...
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Overcoming limitations in current measures of drug response may enable AI-driven precision oncology
Machine learning (ML) models of drug sensitivity prediction are becoming increasingly popular in precision oncology. Here, we identify a fundamental...
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Does restaging MRI radiomics analysis improve pathological complete response prediction in rectal cancer patients? A prognostic model development
PurposeOur study investigated the contribution that the application of radiomics analysis on post-treatment magnetic resonance imaging can add to the...
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Prediction of survival in infants with congenital diaphragmatic hernia and the response to inhaled nitric oxide
The use of inhaled nitric oxide (iNO) in treating pulmonary hypertension in infants with congenital diaphragmatic hernia (CDH) is controversial. Our...
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Dynamic Risk Prediction of Response to Ursodeoxycholic Acid Among Patients with Primary Biliary Cholangitis in the USA
BackgroundUrsodeoxycholic acid (UDCA) remains the first-line therapy for primary biliary cholangitis (PBC); however, inadequate treatment response...
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Early non-response as a predictor of later non-response to antipsychotics in schizophrenia: a randomized trial
BackgroundIt remains a challenge to predict the long-term response to antipsychotics in patients with schizophrenia who do not respond at an early...
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MicroRNAs serve as prediction and treatment-response biomarkers of attention-deficit/hyperactivity disorder and promote the differentiation of neuronal cells by repressing the apoptosis pathway
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder. This study aimed to examine whether miRNA...
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Improved prediction of prognosis and therapy response for lung adenocarcinoma after identification of DNA-directed RNA polymerase-associated lncRNAs
BackgroundDNA-directed RNA polymerase (DDRP) related genes and long non-coding RNAs (lncRNAs) play an important role in the development of lung...
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Prediction of the Efficacy of Lumbar Sympathetic Block in Patients with Lower Extremity Complex Regional Pain Syndrome Type 1 Based on the Sympathetic Skin Response
IntroductionComplex regional pain syndrome type 1 (CRPS-1) is prevalent after trauma, with intractable pain being the most prominent clinical...
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Patient-derived organoids of pancreatic ductal adenocarcinoma for subtype determination and clinical outcome prediction
BackgroundRecently, two molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) have been proposed: the “Classical” and “Basal-like” subtypes,...
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[18F]FDG PET/MRI enables early chemotherapy response prediction in pancreatic ductal adenocarcinoma
PurposeIn this prospective exploratory study, we evaluated the feasibility of [ 18 F]fluorodeoxyglucose ([ 18 F]FDG) PET/MRI-based chemotherapy response...
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Prospective validation of a biomarker-driven response prediction model to romiplostim in lower-risk myelodysplastic neoplasms – results of the EUROPE trial by EMSCO
The EUROPE phase 2 trial investigated the predictive value of biomarkers on the clinical efficacy of single agent romiplostim (ROM) treatment in...
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Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial
The stomach-derived hormone ghrelin plays not only a role in feeding, starvation, and survival, but it has been suggested to also be involved in the...