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Genetically encoded sensors enable micro- and nano-scopic decoding of transmission in healthy and diseased brains
Neural communication orchestrates a variety of behaviors, yet despite impressive effort, delineating transmission properties of neuromodulatory...
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A multicentric IT platform for storage and sharing of imaging-based radiation dosimetric data
PurposeThe MEDIRAD project is about the effects of low radiation dose in the context of medical procedures. The goal of the work is to develop an...
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BBTCD: blockchain based traceability of counterfeited drugs
The supply chain is a complex network in healthcare that crosses organizational and geographical borders. The inherent complexity of such structures...
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Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction
Targeting cyclin-dependent kinases (CDKs) has recently emerged as a promising therapeutic approach against cancer. However, the anticancer mechanisms...
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FAIRness through automation: development of an automated medical data integration infrastructure for FAIR health data in a maximum care university hospital
BackgroundSecondary use of routine medical data is key to large-scale clinical and health services research. In a maximum care hospital, the volume...
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Intelligent Telehealth in Pharmacovigilance: A Future Perspective
Pharmacovigilance improves patient safety by detecting and preventing adverse drug events. However, challenges exist that limit adverse drug event...
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Proapoptotic and proautophagy effect of H1-receptor antagonist desloratadine in human glioblastoma cell lines
Glioblastomas are aggressive and usually incurable high-grade gliomas without adequate treatment. In this study, we aimed to investigate the...
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Neuroprotective effects of morroniside from Cornus officinalis sieb. Et zucc against Parkinson’s disease via inhibiting oxidative stress and ferroptosis
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer disease accompanied by the death of dopaminergic...
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XPO1 inhibition displays anti-leukemia efficacy against DNMT3A-mutant acute myeloid leukemia via downregulating glutathione pathway
Acute myeloid leukemia (AML) patients with DNA methyltransferase 3A (DNMT3A) mutation display poor prognosis, and targeted therapy is not available...
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LncRNA GAS5-hnRNPK axis inhibited ovarian cancer progression via inhibition of AKT signaling in ovarian cancer cells
BackgroundThe incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first.
MethodsThe expression of...
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The implications of 5G technology on cardiothoracic surgical services in India
The fifth-generation (5G) technology is finally making its long-anticipated arrival in India, where it has evoked much hope to advance healthcare...
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An Orchestration Platform that Puts Radiologists in the Driver’s Seat of AI Innovation: a Methodological Approach
Current AI-driven research in radiology requires resources and expertise that are often inaccessible to small and resource-limited labs. The...
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A FHIR has been lit on gICS: facilitating the standardised exchange of informed consent in a large network of university medicine
BackgroundThe Federal Ministry of Education and Research of Germany (BMBF) funds a network of university medicines (NUM) to support COVID-19 and...
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Switchable CAR T cell strategy against osteosarcoma
Immunotherapy with chimeric antigen receptor T (CAR T) cells has changed the treatment of hematological malignances, but they are still a challenge...
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Interoperability and Considerations for Standards-Based Exchange of Medical Images: HIMSS-SIIM Collaborative White Paper
This white paper explores the considerations of standards-based interoperability of medical images between organizations, patients, and providers. In...
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Workflow Integration of Research AI Tools into a Hospital Radiology Rapid Prototy** Environment
The field of artificial intelligence (AI) in medical imaging is undergoing explosive growth, and Radiology is a prime target for innovation. The...
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E-Consent—a guide to maintain recruitment in clinical trials during the COVID-19 pandemic
BackgroundThe COVID-19 pandemic has posed daunting challenges when conducting clinical research. Adopting new technologies such as remote electronic...
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Cloud Computing Mobile Application for Remote Monitoring of Bell’s Palsy
Mobile applications provide the healthcare industry with a means of connecting with patients in their own home utilizing their own personal mobile...
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Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism
Gastric cancer (GC) is among the most lethal malignancies due to its poor early diagnosis and high metastasis rate, and new therapeutic targets are...
