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ICG fluorescence imaging in colorectal surgery: a snapshot from the ICRAL study group
BackgroundFluorescence-guided visualization is a recently proposed technology in colorectal surgery. Possible uses include evaluating perfusion,...
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Indocyanine green fluorescence-guided laparoscopic colorectal cancer surgery with prophylactic retrograde transileal conduit ureteral catheter placement after previous total cystectomy: a case report
BackgroundIatrogenic ureteral injury (UI) is a potentially serious complication of colorectal cancer surgery. Performing perioperative placement of...
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Effects of indocyanine green fluorescence imaging of laparoscopic anatomic liver resection for HCC: a propensity score-matched study
BackgroundRecently, indocyanine green (ICG) fluorescence imaging has been increasingly used in laparoscopic anatomic liver resection. The aim of...
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Laparoscopic ultrasound-guided superselective portal vein injection combined with real-time indocyanine green fluorescence imaging and navigation for accurate resection of localized intrahepatic bile duct dilatation: a case report
BackgroundPrimary intrahepatic bile duct dilatation can be very harmful to patients although it belongs to benign biliary disease. It can occur in...
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Neoadjuvant Therapies Do Not Reduce Epidermal Growth Factor Receptor (EGFR) Expression or EGFR-Targeted Fluorescence in a Murine Model of Soft-Tissue Sarcomas
PurposeABY-029, an epidermal growth factor receptor (EGFR)-targeted, synthetic Affibody peptide labeled with a near-infrared fluorophore, is under...
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Intraoperative 5-ALA fluorescence-guided resection of high-grade glioma leads to greater extent of resection with better outcomes: a systematic review
ImportanceHigh-grade gliomas (HGG) are the most aggressive and common malignant brain tumors in adults. They have a dismally fatal prognosis. Even if...
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Benefits of combined use of 68−Ga Dotatoc and 5-ALA fluorescence for recurrent atypical skull-base meningioma after previous microsurgery and Gamma Knife radiosurgery: a case report
BackgroundStudies of novel microsurgical adjuncts, such as 5-aminolevulinic acid (5-ALA) fluorescence have shown various fluorescence patterns within...
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Fluorescence grid analysis for the evaluation of piecemeal surgery in sinonasal inverted papilloma: a proof-of-concept study
PurposeLocal recurrence occurs in ~ 19% of sinonasal inverted papilloma (SNIP) surgeries and is strongly associated with incomplete resection. During...
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Laparoscopic left hemihepatectomy using augmented reality navigation plus ICG fluorescence imaging for hepatolithiasis: a retrospective single-arm cohort study (with video)
BackgroundLaparoscopic left hemihepatectomy (LLH) has been shown to be an effective and safe method for treating hepatolithiasis primarily affecting...
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Laparoscopic modular extended right posterior sectionectomy for hepatocellular carcinoma guided by projection plane extension from the right hepatic vein
BackgroundExtended right posterior sectionectomy (ERPS) preserves more liver parenchyma than right hepatectomy when hepatocellular carcinoma (HCC) is...
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Safety and efficacy of preoperative indocyanine green fluorescence marking in laparoscopic gastrectomy for proximal gastric and esophagogastric junction adenocarcinoma (ICG MAP study)
PurposeThe incidence of adenocarcinoma of the esophagogastric junction (AEG) and proximal gastric cancer (PGC) is rising worldwide. Recently, the use...
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Fluorescence-based sentinel lymph node map** and lymphography evaluation: results from the IHU-IRCAD-EAES EURO-FIGS registry
BackgroundThe identification of metastatic lymph nodes is one of the most important prognostic factors in gastrointestinal (GI) cancers....
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Presurgical computed tomography-guided localization of lung ground glass nodules: comparing hook-wire and indocyanine green
BackgroundPresurgical computed tomography (CT)-guided localization is frequently employed to reduce the thoracotomy conversion rate, while increasing...
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Effective application of indocyanine green for visualization of the thoracic duct during video-assisted thoracoscopic surgery for chylothorax: a case report
BackgroundChylothorax is an accumulation of typically milky-appearing lymphatic fluid within the pleural cavity. High-output chylothorax may lead to...
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Fluorescein-guided resection of a left frontal pre-rolandic cerebral metastasis: how I do it
BackgroundCerebral metastases (CM) are the most common intracranial tumors; several studies have underlined the fundamental role of neurosurgical...
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First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy
PurposeProstate-specific membrane antigen (PSMA) is increasingly used to image prostate cancer in clinical practice. We sought to develop and test a...
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RGD-functionalised melanin nanoparticles for intraoperative photoacoustic imaging-guided breast cancer surgery
PurposeObtaining tumour-free margins is critical for avoiding re-excision and reducing local recurrence following breast-conserving surgery; however,...