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5-Methylcytosine-related lncRNAs: predicting prognosis and identifying hot and cold tumor subtypes in head and neck squamous cell carcinoma
Background5-Methylcytosine (m 5 C) methylation is recognized as an mRNA modification that participates in biological progression by regulating related...
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The functions, oncogenic roles, and clinical significance of circular RNAs in renal cell carcinoma
Renal cell carcinoma (RCC) is the most common form of malignancy affecting the kidneys. Circular RNAs (circRNAs) are non-coding RNAs that are derived...
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Identification and development of a novel risk model based on cuproptosis-associated RNA methylation regulators for predicting prognosis and characterizing immune status in hepatocellular carcinoma
BackgroundCuproptosis, a novel cell death caused by excess copper, is quite obscure in hepatocellular carcinoma (HCC) and needs more investigation.
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LncRNA CACClnc promotes chemoresistance of colorectal cancer by modulating alternative splicing of RAD51
Long non-coding RNAs (lncRNAs) play important roles in carcinogenesis. However, the effect of lncRNA on chemoresistance and RNA alternative splicing...
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RNA modification in cardiovascular disease: implications for therapeutic interventions
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high incidence and a youth-oriented tendency. RNA modification is...
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Unveiling the functional paradigm of exosome-derived long non-coding RNAs (lncRNAs) in cancer: based on a narrative review and systematic review
Background and purposeThe intricate mechanisms underlying intercellular communication within the tumor microenvironment remain largely elusive....
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Prognostic, diagnostic and clinicopathological roles of tsRNAs: a meta-analysis in breast cancer
Breast cancer (BC) is one of the most common malignancies in women and the leading cause of cancer-related death in women. The newly emerged...
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tRNA-derived RNA fragments in cancer: current status and future perspectives
Non-coding RNAs (ncRNAs) have been the focus of many studies over the last few decades, and their fundamental roles in human diseases have been well...
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Glucose dysregulation in antipsychotic-naive first-episode psychosis: in silico exploration of gene expression signatures
Antipsychotic (AP)-naive first-episode psychosis (FEP) patients display early dysglycemia, including insulin resistance and prediabetes. Metabolic...
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The role of LncRNAs and CircRNAs in osteoporosis: a focus on osteogenesis and osteoclastogenesis signaling pathways
BackgroundOsteoporosis is a crucial health concern interconnected with physical disabilities as well as financial burdens. It arises from an...
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Exploring the enigma: history, present, and future of long non-coding RNAs in cancer
Long noncoding RNAs (lncRNAs), which are more than 200 nucleotides in length and do not encode proteins, play crucial roles in governing gene...
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DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth
Transient early endosome (EE)-mitochondria interactions can mediate mitochondrial iron translocation, but the associated mechanisms are still...
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Coordination of RNA modifications in the brain and beyond
Gene expression regulation is a critical process throughout the body, especially in the nervous system. One mechanism by which biological systems...
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Mutual interaction of lncRNAs and epigenetics: focusing on cancer
Long noncoding RNAs are characterized as noncoding transcripts longer than 200 nucleotides in response to a variety of functions within the cells....
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Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications
BackgroundPolycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive ages. Our previous study has implicated...
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Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis
Hepatocellular carcinoma (HCC), which makes up the majority of liver cancer, is induced by the infection of hepatitis B/C virus. Biomarkers are...
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RNA modifications in hematological malignancies
RNA modifications play an important role in various cancers including blood cancers by controlling gene expression programs critical for survival,...
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RNA modifications in cellular metabolism: implications for metabolism-targeted therapy and immunotherapy
Cellular metabolism is an intricate network satisfying bioenergetic and biosynthesis requirements of cells. Relevant studies have been constantly...
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RETRACTED ARTICLE: Long non-coding RNA GATA6-AS1 upregulates GATA6 to regulate the biological behaviors of lung adenocarcinoma cells
BackgroundLung adenocarcinoma (LUAD) is known to be one of the leading causes of cancer-related deaths globally. In recent decades, long non-coding...
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Targeting cardiomyocyte cell cycle regulation in heart failure
Heart failure continues to be a significant global health concern, causing substantial morbidity and mortality. The limited ability of the adult...
