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Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes mellitus: a cross-sectional cohort study
This study aimed to investigate the correlation between serum miR-154-5p and urinary albumin to creatinine ratio (UACR) in patients with type 2...
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Sodium intake and urinary losses in children on dialysis: a European multicenter prospective study
BackgroundSodium (Na) balance is unexplored in dialyzed children. We assessed a simplified sodium balance (sNaB) and its correlates in pediatric...
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Independent associations of urinary albumin-to-creatinine ratio and serum cystatin C with carotid intima-media thickness in community-living Taiwanese adults
BackgroundRenal function is a key factor of cardiovascular disease. Carotid intima-media thickness (IMT) has been widely used as a marker of early...
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Effect of urinary glucose concentration and pH on signal intensity in magnetic resonance images
PurposeWith advances in anti-diabetes drugs, increasing numbers of patients have high urinary glucose concentrations, which may alter magnetic...
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Urine albumin-to-creatinine ratio on admission predicts early rehospitalization in patients with acute decompensated heart failure
Detecting high-risk patients for early rehospitalization is crucial in heart failure patient care. An association of albuminuria with cardiovascular...
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A urinary peptidomics approach for early stages of cardiovascular disease risk: The African-PREDICT study
Cardiovascular disease (CVD) affects individuals across the lifespan, with multiple cardiovascular (CV) risk factors increasingly present in young...
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Interstitial washdown and vascular albumin refill during fluid infusion: novel kinetic analysis from three clinical trials
Background and aimsIncreased capillary filtration may paradoxically accelerate vascular refill of both fluid and albumin from the interstitial space,...
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Obesity and glomerular filtration rate
Obesity has received considerable attention in general medicine and nephrology over the last few years. This condition increases the risk of...
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Esaxerenone: blood pressure reduction and cardiorenal protection without reflex sympathetic activation in salt-loaded stroke-prone spontaneously hypertensive rats
Mineralocorticoid receptor (MR) is involved in the mechanisms of blood pressure elevation, organ fibrosis, and inflammation. MR antagonists have been...
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Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study
Hypertension is common in black populations and is known to be associated with low nitric oxide (NO) bioavailability. We compared plasma and urinary...
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Seasonality in nighttime blood pressure and its associations with target organ damage
There is some evidence that nighttime blood pressure varies between seasons. In the present analysis, we investigated the seasonal variation in...
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The application of new complex indicators in the detection of urine
BackgroundAccurate diagnosis and assessment of hematuria is crucial for the early detection of chronic kidney disease(CKD). As instability of urinary...
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Do old urinary biomarkers have a place in the new definition of hepatorenal syndrome in the Egyptian cirrhotic patients? A single-center experience
BackgroundHepatorenal syndrome is still a diagnosis of exclusion despite new classification.
AimsTo validate the accuracy of urinary neutrophil...
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Urinary complement proteins and risk of end-stage renal disease: quantitative urinary proteomics in patients with type 2 diabetes and biopsy-proven diabetic nephropathy
PurposeTo investigate the association between urinary complement proteins and renal outcome in biopsy-proven diabetic nephropathy (DN).
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Niclosamide from an anthelmintic drug to a promising adjuvant therapy for diabetic kidney disease: randomized clinical trial
BackgroundDiabetic kidney disease (DKD) is a serious complication that begins with albuminuria and often leads to a rapid progressive decline in...
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Beraprost Sodium Delays the Decline of Glomerular Filtration Rate in Patients with Diabetic Nephropathy: A Retrospective Study
IntroductionTo investigate the reno-protective effect of beraprost sodium (BPS) in patients with diabetic nephropathy (DN).
MethodsWe...
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A case of Dent disease type 2 with large deletion of OCRL diagnosed after close examination of a school urinary test
A 7-year-old boy visited our hospital for a detailed examination of proteinuria identified in a school urinary test. He had short stature, misaligned...
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Beneficial effects of time and energy restriction diets on the development of experimental acute kidney injury in Rat: Bax/Bcl-2 and histopathological evaluation
People’s lifestyles and, especially, their eating habits affect their health and the functioning of the organs in their bodies, including the...
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Association between the urinary sodium-to-potassium ratio and renal outcomes in patients with chronic kidney disease: a prospective cohort study
A higher urinary sodium-to-potassium (UNa/K) ratio has been reported to be associated with high blood pressure and subsequent cardiovascular events....
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Oral alkalinizing supplementation suppressed intrarenal reactive oxidative stress in mild-stage chronic kidney disease: a randomized cohort study
BackgroundThe beneficial effects of oral supplements with alkalinizing agents in patients with chronic kidney disease (CKD) have been limited to the...
