Search

Search Results

1. Natural killer cell homing and trafficking in tissues and tumors: from biology to application

   Natural killer (NK) cells, a subgroup of innate lymphoid cells, act as the first line of defense against cancer. Although some evidence shows that NK...

   Guang he Ran, Yu qing Lin, ... You cai Deng in Signal Transduction and Targeted Therapy

   Article Open access 29 June 2022
   

2. Diagnostic and therapeutic impact of PET/CT with 18F-DCFPyL versus 18F-Fluorocholine in initial staging of intermediate-/high-risk prostate cancer: a pilot study

   Aim

   To assess the diagnostic and therapeutic impact of PET/CT with 18F-DCFPyL with respect to 18F-Fluorocholine in initial staging of...

   Cristina Lucas Lucas, Laura García Zoghby, ... Ana María García Vicente in Annals of Nuclear Medicine

   Article 02 August 2023
   

3. At-home testing to mitigate community transmission of SARS-CoV-2: protocol for a public health intervention with a nested prospective cohort study

   Background

   The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve as a global health...

   Emily J. Ciccone, Donaldson F. Conserve, ... Giselle Corbie-Smith in BMC Public Health

   Article Open access 04 December 2021
   

4. Targeting a disintegrin and metalloprotease (ADAM) 17-CD122 axis enhances CD8⁺ T cell effector differentiation and anti-tumor immunity

   CD8 ⁺ T cell immune responses are regulated by multi-layer networks, while the post-translational regulation remains largely unknown. Transmembrane...

   Lina Sun, Anjun Jiao, ... Baojun Zhang in Signal Transduction and Targeted Therapy

   Article Open access 26 June 2024
   

5. LAMTOR5 raises abnormal initiation of O-glycosylation in breast cancer metastasis via modulating GALNT1 activity

   During malignancy, perturbed O -glycosylation confers global influence on cancer progression. As a hallmark of cancer metastasis, GalNAc-type O -glycosy...

   Run** Fang, Feifei Xu, ... Lihong Ye in Oncogene

   Article 13 December 2019
   

6. Machine Learning-Based Multiparametric Magnetic Resonance Imaging Radiomics Model for Preoperative Predicting the Deep Stromal Invasion in Patients with Early Cervical Cancer

   Deep stromal invasion is an important pathological factor associated with the treatments and prognosis of cervical cancer patients. Accurate...

   Haowen Yan, Gaoting Huang, ... Zhiming **ang in Journal of Imaging Informatics in Medicine

   Article Open access 10 January 2024
   

7. Role of PSMA-targeted PET-CT in renal cell carcinoma: a systematic review and meta-analysis

   Fluoro-deoxy glucose positron emission tomography/computed tomography (PET/CT), the workhorse of nuclear medicine, has limited utility for renal cell...

   Tejasvini Singhal, Parneet Singh, ... Kanhaiyalal Agrawal in Annals of Nuclear Medicine

   Article 10 February 2024
   

8. Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

   Prostate cancer is the most common cancer in men and it is estimated that over 350,000 men worldwide die of prostate cancer every year. There remains...

   Emma Scott, Kirsty Hodgson, ... Jennifer Munkley in Oncogene

   Article Open access 01 February 2023
   

9. Autologous stem cell transplantation in tandem with Anti-CD30 CAR T-cell infusion in relapsed/refractory CD30⁺ lymphoma

   Background

   Long-term outcome is unfavourable for relapsed/refractory (r/r) lymphoma patients who are resistant to salvage chemotherapy, even after...

   Peiling Zhang, **uxiu Yang, ... Liang Huang in Experimental Hematology & Oncology

   Article Open access 17 October 2022
   

10. Recovery of intracellular glucose uptake in T cells during partial remission of type 1 diabetes

    Aims/hypothesis

    Notwithstanding the irreversible beta cell failure seen in type 1 diabetes, some individuals may experience a special phase named...

    Rong Tang, Ting Zhong, ... **a Li in Diabetologia

    Article 10 June 2023
    

11. Cadherin-17 as a target for the immunoPET of adenocarcinoma

    Purpose

    Cadherin-17 (CDH17) is a calcium-dependent cell adhesion protein that is overexpressed in several adenocarcinomas, including gastric,...

    Samantha Delaney, Outi Keinänen, ... Brian M. Zeglis in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 16 April 2024
    

12. High-dimensional map** of human CEACAM1 expression on immune cells and association with melanoma drug resistance

    Background

    Human carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1) is an inhibitory cell surface protein that functions through homophilic...

    Yu-Hwa Huang, Charles H. Yoon, ... Richard S. Blumberg in Communications Medicine

    Article Open access 02 July 2024
    

13. Comparative study of two laboratory techniques for the detection of HLA-B27 in patients with axial spondyloarthritis: a cross-sectional analysis

    Background

    The diagnostic and prognostic relevance of Human Leukocyte Antigen B-27 (HLA-B27) in Axial Spondyloarthritis (AxSpA) is undeniable, with...

    Ricardo dos Santos Angeli, André Lucas Ribeiro, ... Odirlei André Monticielo in Advances in Rheumatology

    Article Open access 23 May 2024
    

14. B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV

    Background

    Limited longitudinal data are available on immune response to mRNA SARS-CoV-2 vaccination in people living with HIV (PLWHIV); therefore,...

    Jacopo Polvere, Massimiliano Fabbiani, ... Donata Medaglini in Communications Medicine

    Article Open access 30 January 2023
    

15. Tissue-Resident Memory T Cells in Allergy

    Tissue-resident memory T (TRM) cells constitute a distinct subset within the memory T cell population, serving as the vanguard against invading...

    Bo** Long, Shican Zhou, ... Shaoqing Yu in Clinical Reviews in Allergy & Immunology

    Article 21 February 2024
    

16. Teplizumab: First Approval

    Teplizumab (teplizumab-mzwv; TZIELD™) is a CD3-directed monoclonal antibody (humanized IgG1κ) that is being developed by Provention Bio, Inc. for the...

    Susan J. Keam in Drugs

    Article 06 March 2023
    

17. Bruton tyrosine kinase inhibitors in B-cell lymphoma: beyond the antitumour effect

    Targeting B-cell receptor signalling using Bruton tyrosine kinase (BTK) inhibitors (BTKis) has become a highly successful treatment modality for...

    Haoran Wang, Hao Guo, ... Keshu Zhou in Experimental Hematology & Oncology

    Article Open access 22 September 2022
    

18. Dynamic single-cell map** unveils Epstein‒Barr virus-imprinted T-cell exhaustion and on-treatment response

    Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted...

    Miao-Zhen Qiu, Chaoye Wang, ... Rui-Hua Xu in Signal Transduction and Targeted Therapy

    Article Open access 21 September 2023
    

19. Clinical implications of T cell exhaustion for cancer immunotherapy

    Immunotherapy has been a remarkable clinical advancement in the treatment of cancer. T cells are pivotal to the efficacy of current cancer...

    Andrew Chow, Karlo Perica, ... Jedd D. Wolchok in Nature Reviews Clinical Oncology

    Article 10 October 2022
    

20. Evaluation of F-18 DOPA PET/CT in the detection of recurrent or metastatic medullary thyroid carcinoma: comparison with GA-68 DOTA-TATE PET/CT

    Objective

    PET imaging with F-18 DOPA (FDOPA) and Ga-68 DOTATATE (TATE) shows the most promising results to detect medullary thyroid cancer (MTC)...

    Sertac Asa, Kerim Sonmezoglu, ... Haluk B. Sayman in Annals of Nuclear Medicine

    Article 15 May 2021