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Spectral domain OCT features in type 2 macular telangiectasia (type 2 MacTel): its relevance with clinical staging and visual acuity
BackgroundTo report spectral domain optical coherence tomography (SDOCT) imaging findings in type 2 macular telangiectasia (MacTel) and correlate...
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Volume-rendering three-dimensional image analysis of macular neovascularization in age-related macular degeneration
BackgroundTo visualize and investigate the three-dimensional (3D) images of macular neovascularization (MNV) in eyes with neovascular age-related...
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Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma
PurposeTo describe the visual acuity and anatomic outcomes of intravitreal methotrexate (MTX) for the treatment of primary vitreoretinal lymphoma...
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Clinically applicable deep learning-based decision aids for treatment of neovascular AMD
PurposeAnti-vascular endothelial growth factor (Anti-VEGF) therapy is currently seen as the standard for treatment of neovascular AMD (nAMD)....
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Structural OCT and OCT angiography biomarkers associated with the development and progression of geographic atrophy in AMD
BackgroundGeographic atrophy (GA) is an advanced, irreversible, and progressive form of age-related macular degeneration (AMD). Structural optical...
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Surgical Management of Diabetic Macular Edema
Purpose of ReviewDiabetic macular edema (DME) is the accumulation of fluid in the extracellular space within the macula and is a major cause of...
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Clinical sign and symptom of primary vitreoretinal lymphoma short-time after retinal reattachment surgery: a case report
PurposeTo describe a case of primary vitreoretinal lymphoma (PVRL), initially presented after successful repair of rhegmatogenous retinal detachment...
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Dual-AAV split prime editor corrects the mutation and phenotype in mice with inherited retinal degeneration
The prime editor (PE) can edit genomes with almost any intended changes, including all 12 possible types of base substitutions, small insertions and...
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Topographic analysis of local OCT biomarkers which predict progression to atrophy in age-related macular degeneration
PurposeTo define optical coherence tomography (OCT) biomarkers that precede the development of complete retinal pigment epithelium and outer retinal...
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Safety of intravitreal metoprolol in eyes with central serous chorioretinopathy
PurposeTo investigate ocular safety of intravitreal metoprolol in eyes with central serous chorioretinopathy.
MethodsFive eyes of five patients...
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Vitreoretinal lymphoma: Central nervous system lymphoma risk with unilateral or bilateral ocular tumour. A multicentre collaboration
ObjectivesTo investigate the risk of develo** central nervous system (CNS) lymphoma in patients with vitreoretinal lymphoma (VRL) presenting with...
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Clinicopathological Correlations in Enucleated Globes of Late-Stage Coats Disease with a Review of the Literature
BackgroundCoats disease may cause diagnostic dilemma because of its variable clinical presentation that can be suspicious of retinoblastoma. Late...
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Efficacy and safety of brolucizumab versus aflibercept in patients with neovascular age-related macular degeneration: a randomized trial in Indian patients
BackgroundThe current standard treatment for neovascular age-related macular degeneration (nAMD) involves intravitreal injections of anti-vascular...
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A systematic evaluation of human expert agreement on optical coherence tomography biomarkers using multiple devices
ObjectivesTo assess the agreement in evaluating optical coherence tomography (OCT) variables in the leading macular diseases such as neovascular...
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Cataract surgery in neovascular AMD: impact on visual acuity and disease activity
BackgroundCataract and neovascular age-related macular degeneration (nAMD) often co-exist and both contribute to impaired vision. It has been debated...
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3D Visualization System-Assisted Vitrectomy for Rhegmatogenous Retinal Detachment: Leave Out the Perfluorocarbon Liquid
IntroductionPars plana vitrectomy (PPV) is a primary strategy to restore vision for patients who have rhegmatogenous retinal detachment (RRD)....
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Choroidal arterial abnormality in central serous chorioretinopathy
PurposeTo evaluate the choroidal arterial abnormality in central serous chorioretinopathy (CSC).
MethodsFifty-two eyes from 52 patients with CSC...
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A case of intravascular lymphoma diagnosed with a primary vitreoretinal lymphoma-like fundus lesion
PurposeWe report a case of intravascular lymphoma with primary vitreoretinal lymphoma-like fundus findings.
CaseA 61-year-old man with a one-week...
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NAION or not NAION? A literature review of pathogenesis and differential diagnosis of anterior ischaemic optic neuropathies
PurposeTo offer a comprehensive review of the available data regarding non-arteritic anterior ischaemic optic neuropathy and its phenocopies,...
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Aqueous humor cytokine levels through microarray analysis and a sub-analysis based on optical coherence tomography in wet age-related macular degeneration patients
BackgroundTo identify disease-specific cytokine and growth factor profile differences in the aqueous humor between wet age-related macular...
