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Polymorphism rs143384 GDF5 reduces the risk of knee osteoarthritis development in obese individuals and increases the disease risk in non-obese population
BackgroundWe investigated the effect of obesity on the association of genome-wide associative studies (GWAS)-significant genes with the risk of knee...
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Oral granular cell tumor: a collaborative clinicopathological study of 61 cases
BackgroundGranular Cell Tumor (GCT) is an uncommon benign lesion in the oral cavity whose pathogenesis remains poorly understood. Due to their...
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Intravaginal electrical stimulation associated with pelvic floor muscle training for women with stress urinary incontinence: study protocol for a randomized controlled trial with economic evaluation
IntroductionPelvic floor muscle training (PFMT) exercises and neuromuscular electrical stimulation (NMES) are described as conservative interventions...
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Oral Intramuscular Lipoma with Unusual Clinical Presentation: Differential Diagnosis and Review of the Literature
IntroductionLipoma is a soft tissue neoplasm that frequently affects adults but has a low frequency in the oral cavity. Intramuscular lipoma (IML) is...
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The tongue of the red-eared slider (Trachemys scripta elegans): morphological characterization through gross, light, scanning electron, and immunofluorescence microscopic examination
The red-eared slider ( Trachemys scripta elegans ) is renowned for its remarkable adaptations, yet much of its complex biology remains unknown. In this...
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Mechanisms underlying the predictive power of high skeletal muscle uptake of FDG in amyotrophic lateral sclerosis
BackgroundWe recently reported that enhanced [18F]-fluorodeoxyglucose (FDG) uptake in skeletal muscles predicts disease aggressiveness in patients...
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Comparison of respiratory muscle strength and endurance, maximal oxygen consumption, and fatigue in colorectal cancer survivors with healthy adults
PurposeThis study aimed to evaluate respiratory muscle strength and endurance, maximal oxygen consumption, and fatigue of colorectal cancer (CRC)...
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Improved global response outcome after intradetrusor injection of adult muscle-derived cells for the treatment of underactive bladder
We report on the first regulatory approved clinical trial of a prospective open-label physician-initiated study assessing the safety and efficacy of...
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Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia
Cachexia is a severe complication of cancer that adversely affects the course of the disease, with currently no effective treatments. It is...
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Primary extranodal soft tissue Lennert lymphoma (lymphoepithelioid variant of peripheral T-cell lymphoma, unspecified): a case report and review of the literature
Lennert lymphoma (LeL) is a rare variant of peripheral T-cell lymphoma, not otherwise specified (PTCL/NOS) that is rich in epithelioid histiocytes....
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Multifocal neuropathy and Horner’s syndrome due to disseminated pyomyositis in an intravenous drug user
BackgroundThe formation of abscesses with necrosis within large, striated muscles leads to pyomyositis, a condition relatively rarely encountered...
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High extracellular ATP levels released through pannexin-1 channels mediate inflammation and insulin resistance in skeletal muscle fibres of diet-induced obese mice
Aims/hypothesisSkeletal muscle is a key target organ for insulin’s actions and is the main regulator of blood glucose. In obese individuals and...
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Traumatic Ulcerative Granuloma with Stromal Eosinophilia on the Tongue
BackgroundTraumatic Ulcerative Granuloma with Stromal Eosinophilia, commonly known as Eosinophilic Ulcer, is a reactive solitary and self-limiting...
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SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation
SMYD1, a striated muscle-specific lysine methyltransferase, was originally shown to play a key role in embryonic cardiac development but more...
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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity
Aims/hypothesisMitochondria operate in networks, adapting to external stresses and changes in cellular metabolic demand and are subject to various...
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Risk factors for excessive postoperative exo-drift after unilateral lateral rectus muscle recession and medial rectus muscle resection for intermittent exotropia
BackgroundTo detect significant factors associated with excessive postoperative exo-drift in young patients with intermittent exotropia who had...
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Sports-related lower limb muscle injuries: pattern recognition approach and MRI review
Muscle injuries of the lower limbs are currently the most common sport-related injuries, the impact of which is particularly significant in elite...
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Association Among Age-Related Tongue Muscle Abnormality, Tongue Pressure, and Presbyphagia: A 3D MRI Study
Muscle aging such as sarcopenia adversely affects motor activities. However, few studies have elucidated the aging physiological mechanism of tongue...
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Mitochondrial dysfunction in airways and quadriceps muscle of patients with chronic obstructive pulmonary disease
BackgroundMitochondrial damage and dysfunction have been reported in airway and quadriceps muscle cells of patients with chronic obstructive...
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Lymphatic muscle cells contribute to dysfunction of the synovial lymphatic system in inflammatory arthritis in mice
BackgroundOur previous studies reveal that impaired draining function of the synovial lymphatic vessel (LV) contributes to the pathogenesis of...
