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Showing 81-99 of 99 results
  1. Abstract

    Article 27 June 2022
  2. Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals

    Epidermal growth factor receptors (EGFR, HER2, HER3) activate signal transduction pathways involved in cancer proliferation, apoptosis,...

    Onat Kadioglu, **gming Cao, ... Thomas Efferth in Targeted Oncology
    Article 21 November 2014
  3. Caloric restriction maintains OX40 agonist-mediated tumor immunity and CD4 T cell priming during aging

    Immune responses wane during aging, posing challenges to the potential effectiveness of cancer immunotherapies. We previously demonstrated that in...

    Michelle Farazi, Justine Nguyen, ... Carl E. Ruby in Cancer Immunology, Immunotherapy
    Article Open access 30 March 2014
  4. Exploring the anti-diabetic potential of Australian Aboriginal and Indian Ayurvedic plant extracts using cell-based assays

    Background

    Plant-derived compounds have been used clinically to treat type 2 diabetes for many years as they also exert additional beneficial effects...

    Vandana Gulati, Pankaj Gulati, ... Enzo A Palombo in BMC Complementary and Alternative Medicine
    Article Open access 05 February 2015
  5. Targeting metabolic disorders by natural products

    The most prevalent metabolic disorders are diabetes mellitus, obesity, dyslipidemia, osteoporosis and metabolic syndrome, which are developed when...

    Ozra Tabatabaei-Malazy, Bagher Larijani, Mohammad Abdollahi in Journal of Diabetes & Metabolic Disorders
    Article Open access 08 July 2015
  6. Genomic Analysis of Pterostilbene Predicts Its Antiproliferative Effects Against Pancreatic Cancer In Vitro and In Vivo

    Background

    To investigate the inhibitory role of pterostilbene in pancreatic cancer, we conducted a genomic analysis of pterostilbene-treated...

    Denise Elizabeth McCormack, Patrick Mannal, ... David McFadden in Journal of Gastrointestinal Surgery
    Article 27 March 2012
  7. Abstracts

    Article 20 March 2024
  8. Abstracts

    Article 07 March 2020
  9. Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells

    Background

    Genistein (Gen) exhibits anti-mutagenic and anti-metastatic activities in hepatoma cell lines. Gen has suppressive effects on tumor growth...

    Shulhn-Der Wang, Bor-Chyuan Chen, ... Chia-Chou Yeh in BMC Complementary and Alternative Medicine
    Article Open access 16 January 2014
  10. Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

    Purpose

    Resveratrol (3,5,4′-trihydroxy- trans -stilbene) is a naturally occurring polyphenol with a broad range of possible health benefits, including...

    Izet M. Kapetanovic, Miguel Muzzio, ... David L. McCormick in Cancer Chemotherapy and Pharmacology
    Article 30 November 2010
  11. Gene-Diet Interactions on Colorectal Cancer Risk

    There has been increasing interest lately in understanding how natural dietary antioxidants affect chemoprevention, and recently, there has been a...

    Li-Shu Wang, Chieh-Ti Kuo, ... John F. Lechner in Current Nutrition Reports
    Article Open access 10 July 2012
  12. Pterostilbene Inhibits Pancreatic Cancer In Vitro

    Introduction

    Stilbenes are phenolic compounds present in grapes and blueberries. Resveratrol, a naturally occurring compound present in grapes, has...

    Patrick W. Mannal, Juile A. Alosi, ... David W. McFadden in Journal of Gastrointestinal Surgery
    Article 06 February 2010
  13. Resveratrol and its impact on aging and thyroid function

    Resveratrol, the naturally occurring polyphenolic compound characterized by anti-oxidative, anti-inflammatory and apoptotic properties, appears to...

    Article 23 September 2011
  14. Constitutive activation of glycogen synthase kinase-3β correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer

    Background

    Aberrant regulation of glycogen synthase kinase-3β (GSK-3β) has been implicated in several human cancers; however, it has not been reported...

    Yu ** Cho, Ji Hun Kim, ... Byung Lan Lee in BMC Gastroenterology
    Article Open access 12 August 2010
  15. Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon

    Background

    Blueberries may lower relative risk for cancers of the gastrointestinal tract. Previous work indicated an inhibitory effect of consumed...

    Frank A Simmen, Julie A Frank, ... Ronald L Prior in BMC Gastroenterology
    Article Open access 16 September 2009
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