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Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation
NLRP6 plays a crucial role in maintaining intestinal homeostasis by regulating the interaction between the intestinal mucosa and the microbiota....
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Immunoregulatory and Anti-cancer Activities of Combination Treatment of Novel Four-Herb Formula and Doxorubicin in 4T1-Breast Cancer Bearing Mice
ObjectiveTo investigate the in vivo immunomodulatory and anti-tumor mechanisms of the combined treatment of novel Four-Herb formula (4HF) and...
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Gut microbiota transfer evidence from mother to newborn
Early life microbiota is a risk factor for future diseases. The main purpose of this study was to investigate the transfer of gut microbiota from...
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Association between CD4+ T cell counts and gut microbiota and serum cytokines levels in HIV-infected immunological non-responders
BackgroundCD4 + T cell counts in certain human immunodeficiency virus (HIV)-infected patients called immunological non-responders (INRs) could not...
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Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders diagnosed by impairments in social interactions,...
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Microbiome Composition in Pediatric Populations from Birth to Adolescence: Impact of Diet and Prebiotic and Probiotic Interventions
Diet is a key regulator of microbiome structure and function across the lifespan. Microbial colonization in the first year of life has been actively...
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Whole-genome metagenomic analysis of the oral microbiota in patients with obstructive sleep apnea
PurposeThe oral microbiota is closely associated with systemic health, but few studies have investigated the oral microbiota in patients with...
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Effect of functional food ingredients on gut microbiota in a rodent diabetes model
BackgroundThe gut microbiota has been shown to be involved in the development and severity of type 2 diabetes. The aim of the present study was to...
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Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year
BackgroundRecent studies have reported a dysfunctional gut microbiome in breastfed infants. Probiotics have been used in an attempt to restore the...
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Diet, Microbes, and Cancer Across the Tree of Life: a Systematic Review
Purpose of ReviewCancers are a leading cause of death in humans and for many other species. Diet has often been associated with cancers, and the...
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Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms
Vaccine is the most effective way to prevent the spread of communicable diseases, but the immune response induced by it varies greatly between...
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The Novel Insight of Gut Microbiota from Mouse Model to Clinical Patients and the Role of NF-κB Pathway in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a metabolic disorder characterized by hyperandrogenism and related symptoms in women of reproductive age....
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First bloodstream infection caused by Prevotella copri in a heart failure elderly patient with Prevotella-dominated gut microbiota: a case report
BackgroundBloodstream infection (BSI) is a constant threat for hospitalized patients, and elderly patients are particularly susceptible to BSI caused...
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Leveraging diet to engineer the gut microbiome
Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and rheumatoid arthritis, have distinct clinical presentations but...
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Sophorolipid protects against early-weaning syndrome by improving the gut microenvironment in early-weaned piglets
BackgroundIn animals, weaning stress is the first and most critical stress. Weaning can negatively affect the growth performance of animals...
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Eubiotic effect of rifaximin is associated with decreasing abdominal pain in symptomatic uncomplicated diverticular disease: results from an observational cohort study
BackgroundRifaximin effectively treats symptomatic uncomplicated diverticular disease (SUDD) and has shown eubiotic potential (i.e., an increase in...
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Gut microbial features may influence antiviral IgG levels after vaccination against viral respiratory infectious diseases: the evidence from two-sample bidirectional mendelian randomization
BackgroundVaccination is effective in preventing viral respiratory infectious diseases through protective antibodies and the gut microbiome has been...
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Altered oral microbiome, but normal human papilloma virus prevalence in cartilage-hair hypoplasia patients
BackgroundCartilage-hair hypoplasia (CHH) is a rare syndromic immunodeficiency with metaphyseal chondrodysplasia and increased risk of malignancy. In...
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Can curcumin supplementation reduce plasma levels of gut-derived uremic toxins in hemodialysis patients? A pilot randomized, double-blind, controlled study
BackgroundGut dysbiosis is common in patients with chronic kidney disease (CKD) and is closely related to inflammatory processes. Some nutritional...
