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Guideline “Parkinson’s disease” of the German Society of Neurology (Deutsche Gesellschaft für Neurologie): concepts of care
IntroductionIn 2023, the German Society of Neurology published a new guideline on Parkinson’s disease. An important section dealt with PD care...
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Kinect-based objective assessment for early frailty identification in patients with Parkinson’s disease
BackgroundFrailty is common in Parkinson’s disease (PD) and increases vulnerability to adverse outcomes. Early detection of this syndrome aids in...
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Predictive models of Alzheimer’s disease dementia risk in older adults with mild cognitive impairment: a systematic review and critical appraisal
BackgroundMild cognitive impairment has received widespread attention as a high-risk population for Alzheimer’s disease, and many studies have...
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Online cognitive monitoring technology for people with Parkinson’s disease and REM sleep behavioural disorder
Automated online cognitive assessments are set to revolutionise clinical research and healthcare. However, their applicability for Parkinson’s...
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Pathological mechanisms and treatment of sporadic Parkinson’s disease: past, present, and future
For a special issue, we review studies on the pathogenesis of nigral cell death and the treatment of sporadic Parkinson’s disease (sPD) over the past...
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Creative thinking and cognitive estimation in Parkinson’s disease
BackgroundPatients with Parkinson’s disease (PD) have been reported to exhibit unusual bouts of creativity (e.g., painting, writing), in particular...
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Parkinson’s disease with anxiety: clinical characteristics and their correlation with oxidative stress, inflammation, and pathological proteins
ObjectiveThis study was performed to explore the differences in the clinical characteristics and oxidative stress indicators, inflammatory factors,...
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Soluble TREM2 in body fluid in Alzheimer’s disease and Parkinson’s disease
BackgroundPrevious studies showed conflicting results regarding soluble triggering receptor expressed on myeloid cells 2 (sTREM2) level alteration in...
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Differential associations of clinical features with cerebrospinal fluid biomarkers in dementia with Lewy bodies and Alzheimer’s disease
AimTo explore associations of cerebrospinal fluid biomarkers of neurodegeneration and amyloidosis with caregiver burden, cognition and functionality...
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The role of immune and inflammatory-related indicators in cognitive dysfunction and disease severity in patients with parkinson’s disease
We aimed to explore the role of immune and inflammatory indicators in cognitive dysfunction and disease severity in patients with Parkinson's...
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Association of accelerometer-measured physical activity intensity, sedentary time, and exercise time with incident Parkinson’s disease
Evidence regarding the association between physical activity and Parkinson’s disease (PD) risk is generally limited due to the use of self-report...
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Post-diagnostic support for persons with young-onset dementia – a retrospective analysis based on data from the Swedish dementia registry SveDem
BackgroundApproximately 3.9 million persons worldwide have young-onset dementia. Symptoms related to young-onset dementia present distinct challenges...
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Long-term cognitive decline prediction based on multi-modal data using Multimodal3DSiameseNet: transfer learning from Alzheimer’s disease to Parkinson’s disease
PurposeMonitoring and predicting the cognitive state of subjects with neurodegenerative disorders is crucial to provide appropriate treatment as soon...
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The lived experience of stigma and parkinson’s disease in Kenya: a public health challenge
BackgroundAs a disease characterised by non-motor and very visible motor symptoms, Parkinson’s disease has been associated with multiple forms of...
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Identifying the potential role of serum miR-20a as a biomarker for olfactory dysfunction in patients with Parkinson’s disease
IntroductionOlfactory dysfunction (OD), one of the most common non-motor symptoms in Parkinson’s disease (PD), is a cardinal prodromal symptom that...
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Hyposmia correlates with axial signs and gait disorder in Parkinson’s disease: an Italian Olfactory Identification Test study
BackgroundOlfactory dysfunction is a non-motor symptom and an important biomarker of Parkinson’s disease (PD) because of its high prevalence (> 90%)....
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Lewy Body Dementia: An Overview of Promising Therapeutics
Purpose of ReviewLewy body dementia (LBD) encompasses dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD). This article will...
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Exercise Made Accessible: the Merits of Community-Based Programs for Persons with Parkinson’s Disease
Purpose of ReviewMany studies have identified positive effects of physiotherapy and exercise for persons with Parkinson’s disease (PD). Most work has...
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Targeting sleep and the circadian system as a novel treatment strategy for Parkinson’s disease
There is a growing appreciation of the wide range of sleep–wake disturbances that occur frequently in Parkinson’s disease. These are known to be...
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Tools and criteria to select patients with advanced Parkinson’s disease for device-aided therapies: a narrative review
This article provides an overview of the various screening and selection tools which have been developed over the past 25 years to identify patients...