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Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis
Polygenic risk prediction remains an important aim of genetic association studies. Currently, the predictive power of schizophrenia polygenic risk...
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Effects of photobiomodulation on oxidative stress in rats with type 2 diabetes mellitus
The present study aimed to evaluate photobiomodulation effects on oxidative stress in type 2 diabetes mellitus (DM2). Thirty-one male Wistar rats...
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Flavonoid compound from Agrimonia pilosa Ledeb improves adipose insulin resistance by alleviating oxidative stress and inflammation
BackgroundResearches and practice of traditional Chinese medicine indicated that Agrimonia pilosa Ledeb could improve insulin resistance (IR) and...
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Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction
Diabetes mellitus is a chronic metabolic disease, posing a considerable threat to global public health. Treating systemic comorbidities has been one...
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SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway
AimsTo estimate the effects of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) on proteinuria and oxidative stress expression in type 2...
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Sweet-type star fruit supplementation controls oxidative stress status and enhances the community walking capacity among elderly Thai
BackgroundSweet-type Star fruit (SF) ( Averrhoa carambola L.) is seasonal and more available for purchase in many markets in Thailand, when compared...
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Oxidative stress triggers hyperdynamic circulation via central neural activation in portal hypertensive rats
BackgroundHyperdynamic circulation in portal hypertension (PHT) depends on central neural activation. However, the initiating mechanism that signals...
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Tert-butylhydroquinone prevents cyclophosphamide induce lung toxicity in rats via inhibiting oxidative stress and apoptosis: in vivo and in silico study
BackgroundCyclophosphamide (CP) is a chemotherapeutic and immunosuppressive agent that induces oxidative stress, causing lung tissue damage.
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Ochratoxin A induces mitochondrial dysfunction, oxidative stress, and apoptosis of retinal ganglion cells (RGCs), leading to retinal damage in mice
PurposeOchratoxin A (OTA) contamination of food and feed is a serious problem worldwide. OTA is considered a carcinogen and immunotoxic, nephrotoxic,...
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Intrauterine exposure to oxidative stress induces caspase-1-dependent enteric nerve cell pyroptosis
PurposeThis study determined whether oxidative stress causes the developmental abnormalities of the enteric nervous system during the embryonic...
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Comparison of Effects of Injectable Semaglutide and Dulaglutide on Oxidative Stress and Glucose Variability in Patients with Type 2 Diabetes Mellitus: A Prospective Preliminary Study
IntroductionRecent trials have shown that glucagon-like peptide-1 receptor agonists considerably reduce atherosclerotic cardiovascular disease in...
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Statistical modeling of health space based on metabolic stress and oxidative stress scores
BackgroundHealth space (HS) is a statistical way of visualizing individual’s health status in multi-dimensional space. In this study, we propose a...
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Hepatoprotective effects of N-acetylcysteine on liver injury by irisin upregulation and oxidative stress reduction in diabetic rats
BackgroundThe current study aimed to investigate the oxidative stress in rat liver with diabetes mellitus (DM) as well as the protective effects of...
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Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway
BackgroundAge-related macular degeneration (AMD) is a leading cause of vision loss in elderly people, and dry AMD is the most common type of AMD....
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Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model
IntroductionSarcopenia is a complication of Chronic Obstructive Pulmonary Disease (COPD) that negatively affects physical activity and quality of...
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HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation
BackgroundHSK3486 (ciprofol), a new candidate drug similar to propofol, exerts sedative and hypnotic effects through gamma-aminobutyric acid type A...
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Oleuropein alleviates myocardial ischemia–reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathway
BackgroundMyocardial ischemia/reperfusion injury (MIRI) is an important complication of reperfusion therapy, and has a lack of effective prevention...
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Naturalistic comparison of clomethiazole and Diazepam treatment in alcohol withdrawal: effects on oxidative stress, inflammatory cytokines and hepatic biomarkers
Ethanol is metabolized by alcohol dehydrogenase to acetaldehyde and induces cytochrome P450 2E1 (CYP2E1), which generates reactive oxygen species...
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Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress
Impaired macroautophagy/autophagy flux has been implicated in the treatment of prostate cancer (PCa). However, the mechanism underlying autophagy...
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MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands
Bovine mastitis, the most prevalent and costly disease in dairy cows worldwide, decreases milk quality and quantity, and increases cow culling....