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  1. Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis

    Polygenic risk prediction remains an important aim of genetic association studies. Currently, the predictive power of schizophrenia polygenic risk...

    Giorgio Pistis, Javier Vázquez-Bourgon, ... Kim Q Do in Molecular Psychiatry
    Article Open access 21 September 2022
  2. Effects of photobiomodulation on oxidative stress in rats with type 2 diabetes mellitus

    The present study aimed to evaluate photobiomodulation effects on oxidative stress in type 2 diabetes mellitus (DM2). Thirty-one male Wistar rats...

    Larissa da Silva Tonetto, Carlos Cassiano Figueiró da Silva, ... Rodrigo Boemo Jaenisch in Lasers in Medical Science
    Article 22 March 2023
  3. Flavonoid compound from Agrimonia pilosa Ledeb improves adipose insulin resistance by alleviating oxidative stress and inflammation

    Background

    Researches and practice of traditional Chinese medicine indicated that Agrimonia pilosa Ledeb could improve insulin resistance (IR) and...

    Tingwang Guo, Yun Pan, ... Liancai Zhu in BMC Complementary Medicine and Therapies
    Article Open access 14 September 2023
  4. Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction

    Diabetes mellitus is a chronic metabolic disease, posing a considerable threat to global public health. Treating systemic comorbidities has been one...

    Qi-**ang Song, Yi Sun, ... Margot S. Damaser in Nature Reviews Urology
    Article 16 August 2022
  5. SGLT2i relieve proteinuria in diabetic nephropathy patients potentially by inhibiting renal oxidative stress rather than through AGEs pathway

    Aims

    To estimate the effects of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) on proteinuria and oxidative stress expression in type 2...

    **ao-chun Zeng, Yuan Tian, ... **ao-min Chen in Diabetology & Metabolic Syndrome
    Article Open access 16 February 2024
  6. Sweet-type star fruit supplementation controls oxidative stress status and enhances the community walking capacity among elderly Thai

    Background

    Sweet-type Star fruit (SF) ( Averrhoa carambola L.) is seasonal and more available for purchase in many markets in Thailand, when compared...

    Jynwara Kaju, Jirakrit Leelarungrayub, ... James J Laskin in BMC Complementary Medicine and Therapies
    Article Open access 11 December 2023
  7. Oxidative stress triggers hyperdynamic circulation via central neural activation in portal hypertensive rats

    Background

    Hyperdynamic circulation in portal hypertension (PHT) depends on central neural activation. However, the initiating mechanism that signals...

    Hongqun Liu, Noura Alhassan, ... Samuel S. Lee in Hepatology International
    Article 01 February 2023
  8. Tert-butylhydroquinone prevents cyclophosphamide induce lung toxicity in rats via inhibiting oxidative stress and apoptosis: in vivo and in silico study

    Background

    Cyclophosphamide (CP) is a chemotherapeutic and immunosuppressive agent that induces oxidative stress, causing lung tissue damage.

    ...
    Mahrous A. Ibrahim, Ayman Fathi Elsharawy, ... Gamal Abdelrahman Bakhaat in Egyptian Journal of Forensic Sciences
    Article Open access 07 May 2024
  9. Ochratoxin A induces mitochondrial dysfunction, oxidative stress, and apoptosis of retinal ganglion cells (RGCs), leading to retinal damage in mice

    Purpose

    Ochratoxin A (OTA) contamination of food and feed is a serious problem worldwide. OTA is considered a carcinogen and immunotoxic, nephrotoxic,...

    Miao Fu, Yuanyuan Chen, Anhuai Yang in International Ophthalmology
    Article Open access 13 February 2024
  10. Intrauterine exposure to oxidative stress induces caspase-1-dependent enteric nerve cell pyroptosis

    Purpose

    This study determined whether oxidative stress causes the developmental abnormalities of the enteric nervous system during the embryonic...

    Lingling Zhou, Bingyu Wang, ... Weibing Tang in Pediatric Surgery International
    Article 22 August 2022
  11. Comparison of Effects of Injectable Semaglutide and Dulaglutide on Oxidative Stress and Glucose Variability in Patients with Type 2 Diabetes Mellitus: A Prospective Preliminary Study

    Introduction

    Recent trials have shown that glucagon-like peptide-1 receptor agonists considerably reduce atherosclerotic cardiovascular disease in...

    Takemasa Omachi, Makoto Ohara, ... Sho-ichi Yamagishi in Diabetes Therapy
    Article Open access 25 October 2023
  12. Statistical modeling of health space based on metabolic stress and oxidative stress scores

    Background

    Health space (HS) is a statistical way of visualizing individual’s health status in multi-dimensional space. In this study, we propose a...

    Cheolgyun Park, You** Kim, ... Taesung Park in BMC Public Health
    Article Open access 08 September 2022
  13. Hepatoprotective effects of N-acetylcysteine on liver injury by irisin upregulation and oxidative stress reduction in diabetic rats

    Background

    The current study aimed to investigate the oxidative stress in rat liver with diabetes mellitus (DM) as well as the protective effects of...

    Mehmet Mustafa Erdogan, Mehmet Ali Erdogan, ... Esra Akkus Yetkin in Egyptian Liver Journal
    Article Open access 10 July 2023
  14. Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway

    Background

    Age-related macular degeneration (AMD) is a leading cause of vision loss in elderly people, and dry AMD is the most common type of AMD....

    Yan Wang, Huangxuan Shen, ... **aolan **ang in BMC Complementary Medicine and Therapies
    Article Open access 18 February 2023
  15. Oxidative stress causes muscle structural alterations via p38 MAPK signaling in COPD mouse model

    Introduction

    Sarcopenia is a complication of Chronic Obstructive Pulmonary Disease (COPD) that negatively affects physical activity and quality of...

    Yosuke Mano, Manabu Tsukamoto, ... Akinori Sakai in Journal of Bone and Mineral Metabolism
    Article 26 September 2022
  16. HSK3486 Inhibits Colorectal Cancer Growth by Promoting Oxidative Stress and ATPase Inhibitory Factor 1 Activation

    Background

    HSK3486 (ciprofol), a new candidate drug similar to propofol, exerts sedative and hypnotic effects through gamma-aminobutyric acid type A...

    Ke Nan, Ziwen Zhong, ... Minli Sun in Digestive Diseases and Sciences
    Article 20 February 2024
  17. Oleuropein alleviates myocardial ischemia–reperfusion injury by suppressing oxidative stress and excessive autophagy via TLR4/MAPK signaling pathway

    Background

    Myocardial ischemia/reperfusion injury (MIRI) is an important complication of reperfusion therapy, and has a lack of effective prevention...

    Jia He, Liting Huang, ... Hongwei Gao in Chinese Medicine
    Article Open access 08 April 2024
  18. Naturalistic comparison of clomethiazole and Diazepam treatment in alcohol withdrawal: effects on oxidative stress, inflammatory cytokines and hepatic biomarkers

    Ethanol is metabolized by alcohol dehydrogenase to acetaldehyde and induces cytochrome P450 2E1 (CYP2E1), which generates reactive oxygen species...

    David Strischewski, Amira Kalmar, ... Johann Steiner in European Archives of Psychiatry and Clinical Neuroscience
    Article Open access 08 June 2024
  19. Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress

    Impaired macroautophagy/autophagy flux has been implicated in the treatment of prostate cancer (PCa). However, the mechanism underlying autophagy...

    Haiying Cui, Yao Wang, ... **aokun Gang in Oncogene
    Article 16 November 2023
  20. MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands

    Bovine mastitis, the most prevalent and costly disease in dairy cows worldwide, decreases milk quality and quantity, and increases cow culling....

    Man Zhou, Herman W. Barkema, ... Bo Han in Veterinary Research
    Article Open access 14 September 2023
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