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Performance of a multidisciplinary robotic surgery program at a university hospital (2012–2022)
Robotic-assisted surgery has become widely adopted for its ability to expand the indications for minimally invasive procedures. This technology aims...
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Design of effective outpatient sentinel surveillance for COVID-19 decision-making: a modeling study
BackgroundDecision-makers impose COVID-19 mitigations based on public health indicators such as reported cases, which are sensitive to fluctuations...
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Experience and results after the implementation of a radiology day unit in a reference hospital
BackgroundInterventional radiological procedures have significantly increased in recent years. Most of them are minimally invasive and require a...
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Usefulness of Percutaneous Pedicle Screw Fixation for Treatment of Lower Lumbar Burst (A3-A4) Fractures: Comparative Study with Thoracolumbar Junction Fractures
BackgroundPercutaneous pedicle screw fixation (PPSF) without fusion has been recently recommended in the treatment of thoracolumbar fracture to...
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A comparative evaluation of the strengths of association between different emergency department crowding metrics and repeat visits within 72 hours
ObjectiveWe sought to compare strengths of association among multiple emergency department (ED) input, throughput and output metrics and the outcome...
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Preclinical evaluation of [18F]FB-A20FMDV2 as a selective marker for measuring αVβ6 integrin occupancy using positron emission tomography in rodent lung
PurposeIntegrin α v β 6 belongs to the RGD subset of the integrin family, and its expression levels are a prognostic and theranostic factor in some...
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Utilizing disease transmission and response capacities to optimize covid-19 control in Malaysia
ObjectivesPublic Health Social Measures (PHSM) such as movement restriction movement needed to be adjusted accordingly during the COVID-19 pandemic...
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Extended duration of treatment using reduced-frequency dosing of anti-PD-1 therapy in patients with advanced melanoma and Merkel cell carcinoma
BackgroundOptimal duration of treatment (DoT) with immune checkpoint inhibitors (ICI) in metastatic cancers remains unclear. Many patients,...
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The lncRNA LINC00339-encoded peptide promotes trophoblast adhesion to endometrial cells via MAPK and PI3K-Akt signaling pathways
BackgroundEndometrial receptivity (ER), a pivotal event for successful embryo implantation, refers to the capacity of endometrium to allow the...
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Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
BackgroundPositron emission tomography (PET) is a non-invasive molecular imaging technique that traces the distribution of radiolabeled molecules in...
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In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain
Purpose[ 18 F]SF51 was previously found to have high binding affinity and selectivity for 18 kDa translocator protein (TSPO) in mouse brain. This...
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Experimental observation on a new chimney-shaped mechanical valve completely implanted above the mitral annulus in animals
Current commercially available prosthetic valves suffer from limited size, high requirements for implantation technique, subvalvular structural...
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VESCL: an open source 2D vessel contouring library
PurposeVESCL (pronounced ‘vessel’) is a novel vessel contouring library for computer-assisted 2D vessel contouring and segmentation. VESCL...
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ASXL1/2 mutations and myeloid malignancies
Myeloid malignancies develop through the accumulation of genetic and epigenetic alterations that dysregulate hematopoietic stem cell (HSC)...
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Pineal anlage tumor: a case report and the literature review
PurposePineal anlage tumor is an extremely rare tumor which was considered as a subtype of pineovlatoma with an overall poor prognosis. This...
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Electrophysiology lab efficiency comparison between cryoballoon and point-by-point radiofrequency ablation: a German sub-analysis of the FREEZE Cohort study
BackgroundPulmonary vein isolation (PVI) is recommended to treat paroxysmal and persistent atrial fibrillation (AF). This analysis aimed to assess...
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Analysis of COVID-19 data using neutrosophic Kruskal Wallis H test
BackgroundKruskal-Wallis H test from the bank of classical statistics tests is a well-known nonparametric alternative to a one-way analysis of...
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The impact of quality-adjusted life years on evaluating COVID-19 mitigation strategies: lessons from age-specific vaccination roll-out and variants of concern in Belgium (2020-2022)
BackgroundWhen formulating and evaluating COVID-19 vaccination strategies, an emphasis has been placed on preventing severe disease that overburdens...
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Microglia homeostasis mediated by epigenetic ARID1A regulates neural progenitor cells response and leads to autism-like behaviors
Microglia are resident macrophages of the central nervous system that selectively emerge in embryonic cortical proliferative zones and regulate...
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COVID-19 in the California State Prison System: an Observational Study of Decarceration, Ongoing Risks, and Risk Factors
BackgroundCorrectional institutions nationwide are seeking to mitigate COVID-19-related risks.
ObjectiveTo quantify changes to California’s prison...