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Microbiote et cancer du côlon
Colorectal cancer (CRC) is a major issue for healthcare services. Although genetic and familial inheritance only account for a small amount of the...
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Is methane a new therapeutic gas?
BackgroundMethane is an attractive fuel. Biologically, methanogens in the colon can use carbon dioxide and hydrogen to produce methane as a...
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Biomarkers of chemotherapy-induced diarrhoea: a clinical study of intestinal microbiome alterations, inflammation and circulating matrix metalloproteinases
PurposeA common side effect of chemotherapy treatment is diarrhoea. Unfortunately, the underlying mechanisms of chemotherapy-induced diarrhoea (CD)...
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Lactobacillus acidophilus CRL 1014 improved “gut health” in the SHIME®reactor
BackgroundHow to maintain “gut health” is a goal for scientists throughout the world. Therefore, microbiota management models for testing probiotics,...
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Contributions of the microbial hydrogen economy to colonic homeostasis
Colonic gases are among the most tangible features of digestion, yet physicians are typically unable to offer long-term relief from clinical...
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Methanobrevibacter smithii Is the Predominant Methanogen in Patients with Constipation-Predominant IBS and Methane on Breath
PurposeAmong irritable bowel syndrome (IBS) patients, breath methane producers overwhelmingly have constipation predominance (C-IBS). Although the...
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Intestinal Microbes, Diet, and Colorectal Cancer
Colorectal cancer (CRC) is the most common gastrointestinal cancer, and a significant health care problem globally. Dietary factors, for example high...
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From gut changes to type 2 diabetes remission after gastric bypass surgeries
Increasing evidence suggests that the gut may influence the host’s metabolism and ultimately change the outcomes of type 2 diabetes mellitus (T2DM)....
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Reduced Diversity and Imbalance of Fecal Microbiota in Patients with Ulcerative Colitis
BackgroundClinical observations and experimental colitis models have indicated the importance of intestinal bacteria in the etiology of ulcerative...
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Colonic methanogenesis in vivo and in vitro and fecal pH after resection of colorectal cancer and in healthy intact colon
PurposeWe compared colonic methanogenesis in vivo and in vitro as well as fecal pH in healthy subjects and in patients with resected colorectal...
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The effects of the relict microorganism B. sp. on development, gas exchange, spontaneous motor activity, stress resistance, and survival of Drosophila melanogaster
Relict microorganisms preserved in the permafrost of geological periods possess a unique resistance to unfavorable factors of the internal and...
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Abnormal Breath Testing in IBS: A Meta-Analysis
BackgroundRecent evidence suggests a role for enteric bacteria in the development of symptoms in subjects with irritable bowel syndrome (IBS). The...
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Methane and the Gastrointestinal Tract
IntroductionSeveral gases are produced through enteric fermentation in the intestinal tract. Carbon dioxide, hydrogen, hydrogen sulfide, and methane...
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The environment within: how gut microbiota may influence metabolism and body composition
Obesity, diabetes and consequently atherosclerotic vascular disease have become major health and public health issues worldwide. The increasing and...
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Chronic Abdominal Pain in Children Is Associated with High Prevalence of Abnormal Microbial Fermentation
BackgroundChronic abdominal pain (CAP) in children, a condition that accounts for approximately 25% of pediatric gastroenterology office visits, may...
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Effect of Predominant Methanogenic Flora on Outcome of Lactose Hydrogen Breath Test in Controls and Irritable Bowel Syndrome Patients of North India
The relationship between methanogenic flora and hydrogen (H 2 ) production is considered to be a possible confounding factor in the interpretation of...
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l-2-Hydroxyglutaric aciduria, a disorder of metabolite repair
The neurometabolic disorder l -2-hydroxyglutaric aciduria is caused by mutations in a gene present on chromosome 14q22.1 and encoding l -2-hydroxyglutar...