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Structural features of eyelid connective tissue in patients with primary open-angle glaucoma
PurposeTo study the connective tissue (CT) structure of upper eyelid skin of primary open-angle glaucoma (POAG) patients.
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A new active bone-conduction implant: surgical experiences and audiological outcomes in patients with bilateral congenital microtia
PurposeFirst-generation bone bridges (BBs) have demonstrated favorable safety and audiological benefits in patients with conductive hearing loss....
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Targeting p53 pathways: mechanisms, structures, and advances in therapy
The TP53 tumor suppressor is the most frequently altered gene in human cancers, and has been a major focus of oncology research. The p53 protein is a...
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Characterizing cardiac involvement in amyloidosis using cardiovascular magnetic resonance diffusion tensor imaging
BackgroundIn-vivo cardiovascular magnetic resonance (CMR) diffusion tensor imaging (DTI) allows imaging of alterations of cardiac fiber architecture...
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Is the pacing site closer to the left ventricular septal endocardium in left bundle branch pacing or in left ventricular septal pacing?
PurposeDistinguishing between left bundle branch pacing (LBBP) and left ventricular septal pacing (LVSP) is challenging. This study aimed to compare...
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A novel Pyk2-derived peptide inhibits invadopodia-mediated breast cancer metastasis
Dissemination of cancer cells from the primary tumor into distant body tissues and organs is the leading cause of death in cancer patients. While...
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Genotype and phenotype characteristics of RHO-associated retinitis pigmentosa in the Japanese population
PurposeTo identify the genotypic and phenotypic characteristics of rhodopsin ( RHO) -associated retinitis pigmentosa (RP) in the Japanese population.
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ACL microtrauma: healing through nutrition, modified sports training, and increased recovery time
PurposeSports injuries among youth and adolescent athletes are a growing concern, particularly at the knee. Based on our current understanding of...
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Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention
Aortic blood flow patterns are closely linked to the morphology and function of the left ventricle, aortic valve and aorta. These flow patterns...
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Arthroscopic electrothermal collagen shrinkage for partial scapholunate ligament tears, isolated or with associated triangular fibrocartilage complex injuries: a prospective study
BackgroundTo present the outcomes of arthroscopic electrothermal shrinkage for partial scapholunate (SL) ligament tears, isolated or with associated...
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Minimally Invasive Costal Cartilage Harvesting Incision for Chest Deformity in Microtia Reconstruction
BackgroundChest deformity is a potential complication associated with auricular reconstruction using autologous costal cartilage. The impact of the...
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Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe public health complications in humans. There are currently no...
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Genotype–phenotype relationship and comparison between eastern and western patients with osteogenesis imperfecta
PurposeTo evaluate the genotypic and phenotypic relationship in a large cohort of OI patients and to compare the differences between eastern and...
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Revision Stapes Surgery
Purpose of ReviewThis review briefly covers the history of stapedectomy, discusses the indications and problems encountered with revision surgery,...
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Novel SLFN14 mutation associated with macrothrombocytopenia in a patient with severe haemorrhagic syndrome
BackgroundPlatelet-type bleeding disorder 20 (BDPLT20), as known as SLFN14-related thrombocytopenia, is a rare inherited thrombocytopenia (IT)....
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Can the Elastic of Surgical Face Masks Stimulate Ear Protrusion in Children?
In this period of the Covid-19 pandemic, a protective mask has become a common object of use to contain virus transmission. The imminent need for...
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Otoplasty: Rasps or Puncture Needles? A Clinical Trial
BackgroundUp to 25% of otoplasties can lead to complications, indicating the need for technical refinement. Stenström’s anterior auricular cartilage...
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Computational Modeling Studies of the Roles of Left Ventricular Geometry, Afterload, and Muscle Contractility on Myocardial Strains in Heart Failure with Preserved Ejection Fraction
Global longitudinal strain and circumferential strain are found to be reduced in HFpEF, which some have interpreted that the global left ventricular...
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A rare case with fetal autoimmune heart block and KNCH2 variant–induced long QT syndrome: a controversial opinion on prenatal management strategy
BackgroundAmong all fetal heart block patients, > 50% cases are associated with maternal autoimmune diseases, and such patients should receive...