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Ominous Causes of Headache
Purpose of ReviewWhile primary headaches like migraines or cluster headaches are prevalent and often debilitating, it's the secondary headaches—those...
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Unraveling the MSG-Headache Controversy: an Updated Literature Review
Purpose of ReviewTo review the evidence and role of monosodium glutamate (MSG) as a headache and migraine trigger.
Recent FindingsMSG is a common...
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Current treatment options for cluster headache: limitations and the unmet need for better and specific treatments—a consensus article
AimTreatment for cluster headache is currently based on a trial-and-error approach. The available preventive treatment is unspecific and based on few...
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Pain Related Quality of Life in Neurofibromatosis Type 1: A Narrative Review
Purpose of Review: The purpose of this narrative review is to summarize pain symptomatology and mechanisms in neurofibromatosis type 1 (NF1), discuss...
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Health equity, care access and quality in headache – part 2
BackgroundHeadache disorders are a global public health concern affecting diverse populations. This review examines headache service organizations in...
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Internal stigmatization in patients with chronic migraine and medication overuse headache
ObjectivesInternalized stigma can have profound effects on how individuals with migraines and other primary headache disorders see themselves and...
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Does Tension Headache Have a Central or Peripheral Origin? Current State of Affairs
Purpose of ReviewThe aim of this narrative review is to analyze the evidence about a peripheral or central origin of a tension headache attack in...
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COVID-19 vaccination-related headache showed two different clusters in the long-term course: a prospective multicenter follow-up study (COVA-Head Study)
BackgroundAlthough acute headache following COVID-19 vaccination is widely acknowledged, the long-term progression of these headaches remains poorly...
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MERTK in the rat trigeminal system: a potential novel target for cluster headache?
The trigeminal system is key to the pathophysiology of migraine and cluster headache, two primary headache disorders that share many features....
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Headache, Ophthalmoplegia, “Mirror Pattern Bands”: Two Case Reports
Tolosa-Hunt syndrome (THS) is an idiopathic, granulomatous inflammation in the cavernous sinus, supraorbital fissure or orbit. Although the...
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The applicability research of the diagnostic criteria for 10.2 Heamodialysis-related headache in the international classification of headache disorders-3rd edition
BackgroundHeadache during hemodialysis (HDH) is prevalent but not negligible. Despite the high prevalence of dialysis headaches, they have rarely...
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The effectiveness of manual and exercise therapy on headache intensity and frequency among patients with cervicogenic headache: a systematic review and meta-analysis
BackgroundCervicogenic headache is a secondary headache, and manual therapy is one of the most common treatment choices for this and other types of...
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Effects of PDE-3 inhibition in persistent post-traumatic headache: evidence of cAMP-dependent signaling
BackgroundPhosphodiesterase 3 (PDE-3) inhibition have been implicated in the neurobiologic underpinnings of migraine. Considering the clinical...
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Cross-sectional, hospital-based analysis of headache types using ICHD-3 criteria in the Middle East, Asia, and Africa: the Head-MENAA study
BackgroundHeadaches are frequent neurological disorders that are yet to be unveiled and treated comprehensively worldwide. Bearing in mind that the...
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The headache registry of the German Migraine and Headache Society (DMKG): baseline data of the first 1,351 patients
BackgroundAlthough good treatment options exist for many headache disorders, not all patients benefit and disability continues to be large. To design...
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Racial and Ethnic Disparities in Emergency Department Wait Times for Headache
Headache is a common complaint of individuals seeking treatment in the emergency department (ED). Because pain is subjective, medical evaluation is...
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Clinical characteristics, medication use, and impact of primary headache on daily activities: an observational study using linked online survey and medical claims data in Japan
BackgroundLimited epidemiological data are available for headache disorders in Japan, and no recent studies have reported the impact of several...
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Sphenopalatine ganglion volumetry in episodic cluster headache: from symptom laterality to cranial autonomic symptoms
BackgroundSphenopalatine ganglion (SPG) is a peripheral structure that plays an important role in cluster headache (CH). Hence, a reliable method to...
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Headache in COVID-19 and Long COVID: to Know Facts for Clinical Practice
Purpose of ReviewHeadache is one of the most frequent symptoms of the acute and post-acute phase of COVID-19. Specific epidemiology, clinical...
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Monckeberg’s Medial Sclerosis as a Cause for Headache and Facial Pain
Purpose of ReviewMönckeberg’s medial sclerosis (MMS) is a chronic, non-inflammatory degenerative condition affecting primarily the tunica media of...
