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Protocol for a systematic review and meta-analysis on Janus kinase inhibitors in the management of vitiligo
BackgroundVitiligo is a disease that affects people of all skin shades and can impact their quality of life. Reliable evidence on the effectiveness...
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Radiomics in Cardiovascular Disease Imaging: from Pixels to the Heart of the Problem
Purpose of ReviewThis review of the literature aims to present potential applications of radiomics in cardiovascular radiology and, in particular, in...
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Investigating brain aging trajectory deviations in different brain regions of individuals with schizophrenia using multimodal magnetic resonance imaging and brain-age prediction: a multicenter study
Although many studies on brain-age prediction in patients with schizophrenia have been reported recently, none has predicted brain age based on...
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The effect of on-site CT-derived fractional flow reserve on the management of decision making for patients with stable chest pain (TARGET trial): objective, rationale, and design
BackgroundThe diagnostic accuracy of CT-derived fractional flow reserve (CT-FFR) in clinical application has been well validated. This advanced...
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Near-infrared spectroscopy measured cerebral oxygenation in full-term infants during transition: an observational study
BackgroundBrain is one of the most sensitive organs to hypoxia during resuscitation. NIRS-measured cerebral oxygenation is an evolving brain...
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Evaluation of a Rhodomyrtus tomentosa ethanolic extract for its therapeutic potential on Staphylococcus aureus infections using in vitro and in vivo models of mastitis
An ethanolic extract from Rhodomyrtus tomentosa leaves (RTL) was studied as a natural alternative to control Staphylococcus aureus , which is an...
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Early brain and abdominal oxygenation in extremely low birth weight infants
BackgroundExtremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut...
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Definition of refractory melasma and its treatment: a review
Although patients with refractory melasma have been treated using various methods, there is still no precise definition or summary of the therapies....
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Multimodal MRI-Based Whole-Brain Assessment in Patients In Anoxoischemic Coma by Using 3D Convolutional Neural Networks
BackgroundThere is an unfulfilled need to find the best way to automatically capture, analyze, organize, and merge structural and functional brain...
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Development and validation of personalised risk prediction models for early detection and diagnosis of primary liver cancer among the English primary care population using the QResearch® database: research protocol and statistical analysis plan
Background and research aimThe incidence and mortality of liver cancer have been increasing in the UK in recent years. However, liver cancer is still...
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Association of polygenic risk for bipolar disorder with grey matter structure and white matter integrity in youth
There is a gap in knowledge regarding the polygenic underpinnings of brain anomalies observed in youth bipolar disorder (BD). This study examined the...
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Altered language network lateralization in euthymic bipolar patients: a pilot study
Bipolar patients (BD) in the euthymic phase show almost no symptoms, nevertheless possibility of relapse is still present. We expected to find a...
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White matter alterations in Attention-Deficit/Hyperactivity Disorder (ADHD): a systematic review of 129 diffusion imaging studies with meta-analysis
Aberrant anatomical brain connections in attention-deficit/hyperactivity disorder (ADHD) are reported inconsistently across diffusion weighted...
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Commentary: Facial Aesthetic Dermatological Procedures and Photoprotection in Chinese Populations
The medical literature on aesthetic dermatology has primarily focused on a light-skinned patient population, yet patients of darker skin types have...
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Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure
Childhood trauma is a known risk factor for trauma and stress-related disorders in adulthood. However, limited research has investigated the impact...
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Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography
AimTo evaluate the feasibility of retrospectively detecting and correcting periodical (cardiac and respiratory motion) and non-periodical shifts of...
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Medicinal plant Miconia albicans synergizes with ampicillin and ciprofloxacin against multi-drug resistant Acinetobacter baumannii and Staphylococcus aureus
BackgroundGiven the rising occurrence of antibiotic resistance due to the existence and ongoing development of resistant bacteria and phenotypes, the...
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Structural brain changes in patients with persistent headache after COVID-19 resolution
Headache is among the most frequently reported symptoms after resolution of COVID-19. We assessed structural brain changes using T1- and...
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Reduction in mitochondrial ROS improves oxidative phosphorylation and provides resilience to coronary endothelium in non-reperfused myocardial infarction
Recent studies demonstrated that mitochondrial antioxidant MnSOD that reduces mitochondrial (mito) reactive oxygen species (ROS) helps maintain an...
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Treatment of traumatic hypertrophic scars and keloids: a systematic review of randomized control trials
Exaggerated healing and remodeling after skin injury may cause hypertrophic and keloidal scars, which are associated with functional and quality of...