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Peripartal management of dichorial twin pregnancy in a bicornuate bicollis uterus: a case report and review of the literature
IntroductionThe management of a pregnancy in a bicornuate uterus is particularly challenging. A bicornuate uterus is a rare occurrence and a twin...
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Darbepoetin Alfa for Late-onset Anemia in Neonates with Rhesus Hemolytic Disease
Neonates with Rhesus hemolytic disease can present with anemia beyond 1 wk of age due to bone marrow suppression and low erythropoietin secretion....
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Preparation and consideration for establishment of an isolation maternity unit in a tertiary hospital during COVID-19 pandemic
The SARS-CoV-2 pandemic is rapidly evolving and remains a major health challenge worldwide. With an increase in pregnant women with COVID-19...
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Sulfated polysaccharides of some seaweeds exhibit neuroprotection via mitigation of oxidative stress, cholinergic dysfunction and inhibition of Zn – induced neuronal damage in HT-22 cells
BackgroundSulfated polysaccharides from marine algae are known to possess antioxidative activities, however, their therapeutic role in metal-induced...
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The effect of piglet vitality, birth order, and blood lactate on the piglet growth performances and preweaning survival
BackgroundLitter size is going up in modern pig production. Due to large litter size and increased farrowing duration, newborn piglets, during...
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Antenatal magnesium sulphate administration for fetal neuroprotection: a French national survey
BackgroundMagnesium sulphate (MgSO 4 ) is the only treatment approved for fetal neuroprotection. No information on its use is available in the absence...
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RNA-seq analysis of human trabecular endothelial cells after treatment with timolol maleate
PurposeTimolol maleate (timolol), a β-receptor blocker, reduces intraocular pressure by decreasing aqueous humor production. Timolol reportedly also...
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Gastrodin promotes the regeneration of peripheral nerves by regulating miR-497/BDNF axis
BackgroundGastrodin (GAS), is a kind of phenolic compound extracted from the traditional Chinese herbal medicine Gastrodia elata Blume (GEB). This...
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Respiratory outcomes of neonates born after previable premature rupture of membranes and treated with gentle ventilation
ObjectiveWe aim to describe neonatal respiratory outcomes following previable preterm premature rupture of membranes(PPROM) when gentle ventilation...
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New insights and potential biomarkers for intraventricular hemorrhage in extremely premature infant, case-control study
BackgroundDespite advancements in neonatal care, germinal matrix-intraventricular hemorrhage impacts 20% of very preterm infants, exacerbating their...
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Postnatal maximal weight loss, fluid administration, and outcomes in extremely preterm newborns
ObjectiveEvaluate maximal weight loss (MWL) and total fluid administration (TFA) association in first week after birth with outcomes among extremely...
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Umbilical cord blood versus mesenchymal stem cells for inflammation-induced preterm brain injury in fetal sheep
BackgroundChorioamnionitis and fetal inflammation are principal causes of neuropathology detected after birth, particularly in very preterm infants....
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Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia
BackgroundPerinatal inflammation combined with hypoxia–ischemia (HI) exacerbates injury in the develo** brain. Therapeutic hypothermia (HT) is...
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Cognitive impairments correlate with increased central nervous system immune activation after allogeneic haematopoietic stem cell transplantation
Murine studies indicate that, after allogeneic haematopoietic stem cell transplantation (aHSCT), donor-derived macrophages replace damaged microglia...
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Predictors of antepartum maternal sepsis and effects on neonatal outcomes: a population-based cohort study
ObjectiveTo examine the relationship between maternal sepsis, type of infection, and short-term neonatal outcomes.
Study designWe conducted a...
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Comparison between stem cell therapy and stem cell derived exosomes on induced multiple sclerosis in dogs
BackgroundMultiple sclerosis (MS) is a chronic condition that primarily manifests as demyelination of neuronal axons in the central nervous system,...
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Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates
BackgroundAllopurinol, an xanthine oxidase (XO) inhibitor, is a promising intervention that may provide neuroprotection for neonates with...
