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Optimising the Early-Stage Rehabilitation Process Post-ACL Reconstruction
Outcomes following anterior cruciate ligament reconstruction (ACLR) need improving, with poor return-to-sport rates and a high risk of secondary...
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Emotional problems across development: examining measurement invariance across childhood, adolescence and early adulthood
Emotional problems (anxiety, depression) are prevalent in children, adolescents and young adults with varying ages at onset. Studying developmental...
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When does early palliative care influence aggressive care at the end of life?
BackgroundEarly palliative care improves patient quality of life and influences cancer care. The time frame of early has not been established. Eight...
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A Cost-Effective Analysis of Motivational Interviewing with Palliative Care Versus Usual Care: Results from the Living Well Project
Little is known about the impact of early palliative care (EPC) combined with motivational interviewing (MI) for persons living with AIDS (PWA). We...
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High neuroticism is associated with common late adverse effects in a nationwide sample of long-term breast cancer survivors
PurposeNeuroticism is a basic personality trait characterized by negative emotions triggered by stress such as a breast cancer diagnosis and its...
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Radiographic markers of hip dysplasia in young adults: predictive effect of factors in early life
Background and objectivesAcetabular dysplasia in young adults occurs, despite screening for developmental hip dysplasia (DDH) in the neonatal period....
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Early diffusion-weighted MRI at 3 Tesla detects ischemic changes of the optic nerve in anterior ischemic optic neuropathy
ObjectivesTo assess the impact of timing from visual symptoms’ onset to diffusion-weighted (DW) 3 T MRI completion to detect ischemic changes of the...
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Correlation of Serum Lactate Levels, Perfusion Index and Plethysmography Variability Index With Invasive Blood Pressure in Late Preterm and Term Infants With Shock
ObjectiveTo study the correlation of objective parameters for diagnosing shock viz., perfusion index (PI), plethysmography variability index (PVI)...
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Comparison of lupus patients with early and late onset nephritis: a study in 71 patients from a single referral center
BackgroundNephritis occurs frequently in systemic lupus erythematosus (SLE) and may worsen disease morbidity and mortality. Knowing all...
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Intralesional methotrexate versus 5-flurouracil in the treatment of keratoacanthoma
BackgroundKeratoacanthoma (KA) is a benign neoplasm that affects mainly photodamaged skin. It is locally destructive and may rarely spread. Surgery...
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Graft versus host disease-related eosinophilic fasciitis: cohort description and literature review
BackgroundChronic graft versus host disease (cGVHD) simulating eosinophilic fasciitis (EF) is an underdiagnosed and challenging complication due to...
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Early surgical intervention alleviates sensory symptoms following acute traumatic central cord syndrome
PurposeTo investigate the impact of early versus delayed surgery on sensory abnormalities in acute traumatic central cord syndrome (ATCCS).
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Develo** and validating a multivariable prediction model which predicts progression of intermediate to late age-related macular degeneration—the PINNACLE trial protocol
AimsAge-related macular degeneration (AMD) is characterised by a progressive loss of central vision. Intermediate AMD is a risk factor for...
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Initial presentation for acute low back pain: is early physical therapy associated with healthcare utilization and spending? A retrospective review of a National Database
BackgroundEarly initiation of physical therapy (PT) has been associated with lower healthcare costs and utilization; however, these studies have been...
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Skin involvement in early diffuse cutaneous systemic sclerosis: an unmet clinical need
Diffuse cutaneous systemic sclerosis (dcSSc) is associated with high mortality resulting from early internal-organ involvement. Clinicians therefore...
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Short-course empiric antibiotic therapy for possible early-onset sepsis in the NICU
ObjectiveOn 2/2019, the Neonatal Antimicrobial Stewardship Program at Nationwide Children’s Hospital recommended reducing empirical antibiotic...
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Outcomes of the early endoscopic-assisted suturectomy for treatment of multisuture craniosynostosis
To present the outcomes and adverse events associated with the endoscopic-assisted, minimally invasive suturectomy in patients with multisuture...
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HYPofractionated Adjuvant RadioTherapy in 1 versus 2 weeks in high-risk patients with breast cancer (HYPART): a non-inferiority, open-label, phase III randomised trial
BackgroundBreast cancer is the most common cancer in women. Radiotherapy is an important part of breast cancer treatment after surgery. Breast cancer...
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Real-Life Barriers to Diagnosis of Early Mycosis Fungoides: An International Expert Panel Discussion
Mycosis fungoides (MF) is a rare, primary cutaneous T-cell lymphoma that is challenging to diagnose due to its heterogeneous clinical presentation...
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Clinical and sociodemographic factors associated with late stage cervical cancer diagnosis in Botswana
BackgroundCervical cancer is the leading cause of female cancer mortality in Botswana with the majority of cervical cancer patients presenting with...