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Optimising oncology drug expenditure in Ireland
A combination of improvements in patient survival, increasing treatment duration, and the development of more expensive agents has led to a doubling...
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Hemodialysis treatment of vancomycin-induced drug reaction with eosinophilia and systemic symptoms/drug-induced hypersensitivity syndrome in a patient undergoing peritoneal dialysis
Drug reaction with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome (DIHS), is a severe drug-induced...
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Antibody–drug conjugates in the treatment of lymphoid neoplasms
Antibody-drug conjugates (ADCs) are a new class of monoclonal antibodies with the characteritic to specifically target tumor cells and to deliver a...
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Zebrafish live imaging: a strong weapon in anticancer drug discovery and development
Develo** anticancer drugs is a complex and time-consuming process. The inability of current laboratory models to reflect important aspects of the...
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Differences in drug use behaviors that impact overdose risk among individuals who do and do not use fentanyl test strips for drug checking
BackgroundOpioid-involved overdose continues to rise, largely explained by fentanyl adulteration of the illicit opioid supply. Fentanyl test strips...
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Drug memory reconsolidation: from molecular mechanisms to the clinical context
Since its rediscovery at the beginning of the 21 st Century, memory reconsolidation has been proposed to be a therapeutic target for reducing the...
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Anti-lymphangiogenesis for boosting drug accumulation in tumors
The inadequate tumor accumulation of anti-cancer agents is a major shortcoming of current therapeutic drugs and remains an even more significant...
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Potential drug–drug interactions in patients with non-small cell lung cancer at a university hospital in Turkey
BackgroundThe aim of this study was to determine the drug profile of patients with non-small cell lung cancer (NSCLC) and to identify potential...
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The Role of Genetics in Advancing Cardiometabolic Drug Development
Purpose of ReviewThe objective of this review is to explore the role of genetics in cardiometabolic drug development. The declining costs of...
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Drug therapy problems among hospitalized patients with cardiovascular disease
BackgroundOptimal utilization of cardiovascular drugs is crucial in reducing morbidity and mortality associated with cardiovascular diseases....
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The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients
Most patients with advanced ovarian cancer (OC) relapse and progress despite systemic therapy, pointing to the need for improved and tailored therapy...
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Empagliflozin: a potential anticancer drug
Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is a highly effective and well-tolerated antidiabetic drug. In addition to...
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Fixed drug eruption-induced balanoposthitis: a case report
Fixed Drug Eruptions (FDE) represent a distinctive type of adverse drug reaction, typically characterized by recurring, sharply demarcated skin...
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Drug susceptibility testing of circulating lung cancer cells for personalized treatment
The presence of Circulating tumor cells (CTCs) has been proven to be correlated with disease progression and the patient’s response to treatment....
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A brief overview of drug-induced liver damage
Drug-induced liver injury (DILI) is a prevalent disorder that can be led on by almost all drug types. The majority of benign DILI cases become better...
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Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts
Zebrafish xenotransplantation models are increasingly applied for phenotypic drug screening to identify small compounds for precision oncology....
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Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities
Atypical teratoid/rhabdoid tumors (ATRTs) represent a rare, but aggressive pediatric brain tumor entity. They are genetically defined by alterations...
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Analysis of drug-induced interstitial lung disease caused by herbal medicine using the Japanese Adverse Drug Event Report database
BackgroundDrug-induced interstitial lung disease (DIILD) is a severe adverse event leading to morbidity and mortality. This study evaluated the...
