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Increased estimated remnant-like particle cholesterol is associated with impaired coronary collateralization in patients with coronary chronic total occlusions
AimsThis study intends to explore whether, or to what extent, the estimated remnant-like particle cholesterol was associated with coronary...
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Excimer laser coronary atherectomy prior to paclitaxel-coated balloon angioplasty for de novo coronary artery lesions
This study aimed to evaluate the efficacy and safety of excimer laser coronary atherectomy (ELCA) prior to paclitaxel-coated balloon angioplasty for...
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Epigenetic and epitranscriptomic regulation of axon regeneration
Effective axonal regeneration in the adult mammalian nervous system requires coordination of elevated intrinsic growth capacity and decreased...
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The Effect of Sleep Enhancement Educational Program on Maternal Sleep Quality for Nulliparous Pregnant Women: A Randomized-Controlled Trial
BackgroundPregnancy is a critical period during which women usually do not prefer taking medication. Therefore, non-pharmacological and safe methods...
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Regional homogeneity alterations in multi-frequency bands in tension-type headache: a resting-state fMRI study
ObjectivesIn this study, we aimed to investigate the spontaneous neural activity in the conventional frequency band (0.01−0.08 Hz) and two...
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Assessment of Quadriceps Corticomotor and Spinal-Reflexive Excitability in Individuals with a History of Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis
BackgroundDifferences in the excitability of motor generating neural pathways are reported following anterior cruciate ligament reconstruction (ACLR)...
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Functional progressive resistance exercise versus eccentric muscle control in children with hemiplegia: a randomized controlled trial
BackgroundHistorically, strength exercise in children with CP is not recommended, because it may develop spasticity, which results in difficulty with...
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A study on the correlation of the asymmetric regulation between the periaqueductal gray and the bilateral trigeminal nucleus caudalis in migraine male rats
BackgroundThe study was designed to explore the correlation of the asymmetric regulation between periaqueductal gray (PAG) and bilateral trigeminal...
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Altered trigeminothalamic spontaneous low-frequency oscillations in migraine without aura: a resting-state fMRI study
BackgroundRecent resting-state fMRI studies demonstrated functional dysconnectivity within the central pain matrix in migraineurs. This study aimed...
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Non-Pharmacological Treatment for Chronic Migraine
Purpose of ReviewChronic migraine (CM) affects a large proportion of the population and is a significant source of disability and lost productivity....
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Appropriateness of exercise therapy delivery in chronic low back pain management: cross-sectional online survey of physiotherapy practice in Germany
BackgroundIn Germany, exercise therapy represents the most commonly prescribed physiotherapy service for non-specific, chronic low back pain...
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The effect of implementation of pain neuroscience education and rehabilitation exercise on post-operative pain and recovery after laparoscopic colorectal surgery: a prospective randomized controlled trial
PurposesTo optimize the efficacy of analgesia and post-operative recovery for patients undergoing laparoscopic colorectal surgery by integrating a...
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Teeth clenching can modify the muscle contraction strength of the lower or upper limbs: systematic review
ObjectiveThis systematic review aimed to investigate the evidence of the interaction between teeth clenching and stimulation on the muscles of the...
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The Evolution of Medication Overuse Headache: History, Pathophysiology and Clinical Update
Medication overuse headache (MOH), the development or worsening of chronic headache resulting from frequent and excessive intake of medications used...
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Advances in targeting central sensitization and brain plasticity in chronic pain
Maladaptation in sensory neural plasticity of nociceptive pathways is associated with various types of chronic pain through central sensitization and...
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Construction of an immune predictive model and identification of TRIP6 as a prognostic marker and therapeutic target of CRC by integration of single-cell and bulk RNA-seq data
BackgroundInvestigations elucidating the complex immunological mechanisms involved in colorectal cancer (CRC) and accurately predicting patient...
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Gabapentinoid Benefit and Risk Stratification: Mechanisms Over Myth
IntroductionRecent years have seen a dramatic escalation of off-label prescribing for gabapentin and pregabalin (gabapentinoids) owing in part to...
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Integrative lactylation and tumor microenvironment signature as prognostic and therapeutic biomarkers in skin cutaneous melanoma
BackgroundThe incidence of skin cutaneous melanoma (SKCM), one of the most aggressive and lethal skin tumors, is increasing worldwide. However, for...
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Curriculum and assessment tool for less invasive surfactant administration: an international Delphi consensus study
BackgroundTraining and assessment of operator competence for the less invasive surfactant administration (LISA) procedure vary. This study aimed to...
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No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs
Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major...
