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Autoantibodies against phospholipase A2 receptor in Brazilian patients with glomerular diseases
BackgroundRecently, great progress has been made in understanding the pathogenesis of membranous nephropathy (MN) with the discovery of...
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Drug Desensitization Update: Key Concepts and Mechanisms
Purpose of ReviewDrug allergy is a worldwide healthcare problem, which prevents the use of first-line therapies and associates with increased...
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For the Long Haul: Management of Long-Term Survivors after Melanoma Systemic Therapy
Purpose of ReviewThis review summarizes the latest advancements in survivorship care for patients with advanced melanoma who received systemic...
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Thrombotic microangiopathies after kidney transplantation in modern era: nosology based on chronology
BackgroundThrombotic microangiopathies (TMAs) are rare but can be severe in kidney transplant.
recipients (KTR).
MethodsWe analysed the epidemiology...
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Current treatment of systemic lupus erythematosus: a clinician's perspective
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Its variable course makes it difficult to standardize patient treatment. This...
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Regulatory T cells in autoimmune kidney diseases and transplantation
Regulatory T (T reg ) cells that express the transcription factor forkhead box protein P3 (FOXP3) are naturally present in the immune system and have...
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Clinical characteristics of patients with systemic lupus erythematosus showing a false-positive result of syphilis screening
A false-positive result of syphilis screening test (FPST) is a characteristic finding in patients with systemic lupus erythematosus (SLE). We...
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Prevalence and Molecular Analysis of Encephalomyocarditis Virus-2 in the Hazel Dormouse
The hazel dormouse ( Muscardinus avellanarius ) population in the UK continues to decline due to habitat loss, despite reintroductions of captive-bred...
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Early graft loss due to acute thrombotic microangiopathy accompanied by complement gene variants in living-related kidney transplantation: case series report
BackgroundRecently, early graft loss has become very rare in living-related kidney transplantation (LKT) as a result of decreased risk of hyperacute...
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Akute Nierenschädigung bei kardiorenalem Syndrom
The incidence of acute kidney injury (AKI) as a result of acute cardiac failure is an increasingly frequent phenomenon driven by demographic change...
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Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet + B cells in systemic lupus erythematosus
BackgroundIn systemic lupus erythematosus (SLE), autoreactive B cells are thought to develop by-passing immune checkpoints and contribute to its...
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Vascular damage in systemic lupus erythematosus
Vascular disease is a major cause of morbidity and mortality in patients with systemic autoimmune diseases, particularly systemic lupus erythematosus...
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Urinary sphingolipids in adolescents and young adults with youth-onset diabetes
BackgroundThis study evaluated urinary sphingolipids as a marker of diabetic kidney disease (DKD) in adolescents and young adults with youth-onset...
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Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells
BackgroundBoth humoral and cellular immune mechanisms are involved in the onset and progression of autoimmune responses in systemic lupus...
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Primary membranous nephropathy: an endless story
Primary membranous nephropathy (PMN) is an autoimmune disease caused by the attack of autoantibodies against podocyte antigens leading to the in situ...
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Adverse Cardiovascular Events in Post-Renal Transplant Patients, a Retrospective Study of Five Hundred Cases Over Twenty-Two Years
BackgroundRenal transplant recipients (RTRs) remain at an increased risk of fatal and non-fatal cardiovascular (CV) events compared to the general...
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Henoch-Schönlein purpura following COVID-19 vaccine in a child: a case report
BackgroundHenoch-Schönlein purpura (HSP) is an IgA-mediated small vessel vasculitis, typical of childhood. It’s a self-limiting disease and it...
