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A distinctive subcortical functional connectivity pattern linking negative affect and treatment outcome in major depressive disorder
Major depressive disorder (MDD) is associated with functional disturbances in subcortical regions. In this naturalistic prospective study...
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Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia
Beyond being one the most widely used psychoactive drugs in the world, cannabis has been identified as an environmental risk factor for psychosis....
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Relationship between [123I]FP-CIT SPECT data and peripheral CD4 + T cell profile in newly-diagnosed drug-naïve Parkinson’s disease patients
BackgroundDysregulation of the CD4 + T cell compartment occurs in Parkinson’s Disease (PD). Nonetheless, the exact relationship with dopamine...
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Multivariate associations between neuroanatomy and cognition in unmedicated and medicated individuals with schizophrenia
Previous studies that focused on univariate correlations between neuroanatomy and cognition in schizophrenia identified some inconsistent findings....
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Trait anxiety is associated with amygdala expectation and caloric taste receipt response across eating disorders
Anxious traits are elevated in eating disorders (EDs), are considered risk factors for ED development, and trait anxiety has been linked to ED...
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A rapid multi-parametric quantitative MR imaging method to assess Parkinson’s disease: a feasibility study
BackgroundMULTIPLEX is a single-scan three-dimensional multi-parametric MRI technique that provides 1 mm isotropic T1-, T2*-, proton density- and...
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The Developmental Trajectories and Long-Term Outcomes of Childhood Tourette Syndrome: a Systematic Review
Purpose of ReviewAlthough much is known about the clinical presentation of Tourette Syndrome (TS), little information exists on the developmental...
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Processing speed dysfunction is associated with functional corticostriatal circuit alterations in childhood epilepsy with centrotemporal spikes: a PET and fMRI study
PurposeEpilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children and usually presents with cognitive dysfunctions....
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Altered white matter structural connectivity in primary Sjögren’s syndrome: a link-based analysis
PurposeCognitive impairment has been revealed in primary Sjögren’s syndrome (pSS). However, the underlying white matter structural connectivity (SC)...
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Brain metabolic changes and clinical response to superolateral medial forebrain bundle deep brain stimulation for treatment-resistant depression
Deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle is an efficacious therapy for treatment-resistant depression,...
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Central obesity is selectively associated with cerebral gray matter atrophy in 15,634 subjects in the UK Biobank
BackgroundObesity is a risk factor for both cardiovascular disease and dementia, but the mechanisms underlying this association are not fully...
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The full spectrum of MRI findings in 18 patients with Canavan disease: new insights into the areas of selective susceptibility
IntroductionCanavan disease (CD) is a rare autosomal recessive neurodegenerative disorder caused by a deficiency of aspartoacylase A, an enzyme that...
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Tau PET imaging in progressive supranuclear palsy: a systematic review and meta-analysis
ObjectivesTo evaluate the difference of tau burden between patients with progressive supranuclear palsy (PSP) and healthy controls (HCs) or other...
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Application of a deep learning image reconstruction (DLIR) algorithm in head CT imaging for children to improve image quality and lesion detection
BackgroundTo evaluate the performance of a Deep Learning Image Reconstruction (DLIR) algorithm in pediatric head CT for improving image quality and...
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The neural signature of psychomotor disturbance in depression
Up to 70% of patients with major depressive disorder present with psychomotor disturbance (PmD), but at the present time understanding of its...
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Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson’s disease
IntroductionAdenosine 2A (A 2A ) receptors co-localize with dopamine D 2 receptors in striatopallidal medium spiny neurons of the indirect pathway. A 2A ...
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A regional brain volume–based age prediction model for neonates and the derived brain maturation index
ObjectiveTo develop a postmenstrual age (PMA) prediction model based on segmentation volume and to evaluate the brain maturation index using the...
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Functional disconnection of the dentate nucleus in essential tremor
Despite previous functional MRI studies on alterations within the cerebello-thalamo-cortical circuit in patients with essential tremor (ET), the...
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Transcriptome alterations are enriched for synapse-associated genes in the striatum of subjects with obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a chronic and severe psychiatric disorder for which effective treatment options are limited. Structural and...
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Age-dependent alterations in the coordinated development of subcortical regions in adolescents with social anxiety disorder
Subcortical brain regions play essential roles in the pathology of social anxiety disorder (SAD). While adolescence is the peak period of SAD, the...
