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Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway
IntroductionHexarelin exhibits significant protection against organ injury in models of ischemia/reperfusion (I/R)-induced injury (IRI)....
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A universal predictive and mechanistic urinary peptide signature in acute kidney injury
BackgroundThe delayed diagnosis of acute kidney injury (AKI) episodes and the lack of specificity of current single AKI biomarkers hamper its...
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Precision management of acute kidney injury in the intensive care unit: current state of the art
Acute kidney injury (AKI) is a prototypical example of a common syndrome in critical illness defined by consensus. The consensus definition for AKI,...
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Validated risk prediction models for outcomes of acute kidney injury: a systematic review
BackgroundAcute Kidney Injury (AKI) is frequently seen in hospitalized and critically ill patients. Studies have shown that AKI is a risk factor for...
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Acute kidney injury in multiple myeloma patients undergoing autologous hematopoietic stem cell transplant: a cohort study
BackgroundAutologous hematopoietic stem cell transplant plays an important role in multiple myeloma (MM) treatment. Increasing incidence of MM and...
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Acute kidney injury requiring dialysis in children: a multicentric, emerging country perspective
BackgroundAcute kidney injury (AKI) is a life-threatening condition, especially in extreme age groups and when kidney replacement therapy (KRT) is...
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Longitudinal assessment of renal function after lung transplantation for cystic fibrosis: transition from post-operative acute kidney injury to acute kidney disease and chronic kidney failure
IntroductionThe clinical trajectory of post-operative acute kidney injury (AKI) following lung transplantation for cystic fibrosis is unknown.
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Effects of sodium-glucose transporter-2 inhibition on systemic hemodynamics, renal function, and intra-renal oxygenation in sepsis-associated acute kidney injury
BackgroundPeople with type 2 diabetes mellitus treated with sodium-glucose transporter-2 inhibitors (SGLT2i) have lower rates of acute kidney injury...
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Risk factors of perioperative acute kidney injury in elderly patients: a single-center retrospective study
PurposeThe elderly are vulnerable to perioperative acute kidney injury. The aim of this study was to determine the risk factors that associated with...
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Dialysis for paediatric acute kidney injury in Cape Town, South Africa
BackgroundDialysis is lifesaving for acute kidney injury (AKI), but access is poor in less resourced settings. A “peritoneal dialysis (PD) first”...
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A proposed framework for advancing acute kidney injury risk stratification and diagnosis in children: a report from the 26th Acute Disease Quality Initiative (ADQI) conference
Acute kidney injury (AKI) in children is associated with increased morbidity, reduced health-related quality of life, greater resource utilization,...
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Neferine alleviates acute kidney injury by regulating the PPAR-α/NF-κB pathway
Acute kidney injury (AKI) is a cluster of clinical syndromes with diverse etiologies that ultimately result in a swift decline in kidney function....
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A single-center clinical study of acute kidney injury associated with acute myocardial infarction
ObjectiveTo investigate the risk factors of acute kidney injury (AKI) patients with acute myocardial infarction (AMI) and establish potential...
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Epidemiology of acute kidney injury in children: a report from the 26th Acute Disease Quality Initiative (ADQI) consensus conference
The nephrology and critical care communities have seen an increase in studies exploring acute kidney injury (AKI) epidemiology in children. As a...
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Early continuous renal replacement therapy for postoperative patient with acute kidney injury following total pancreato-splenectomy: a case report
BackgroundAcute kidney injury is a devastating postoperative complication. Renal replacement therapy is a treatment modality for acute kidney injury....
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Relationship Between Platelet-to-Lymphocyte Count Ratio and Acute Kidney Injury Following Surgery of Stanford Type A Aorta Dissection
ObjectiveThe aim of this study was to evaluate the correlation between the hematological index of platelet to lymphocyte ratio (PLR) and the...
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High preoperative serum strontium levels increase the risk of acute kidney injury after cardiopulmonary bypass
BackgroundAcute kidney injury (AKI) is a common complication of cardiac surgeries. The incidence of AKI after cardiac surgeries using...
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Risk factors for acute kidney injury after pediatric cardiac surgery: a meta-analysis
BackgroundCardiac surgery-associated acute kidney injury (AKI) is associated with increased morbidity and mortality in both adults and children.
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Association of intraoperative cerebral and somatic tissue oxygen saturation with postoperative acute kidney injury in adult patients undergoing multiple valve surgery
BackgroundThe association between tissue oxygenation with postoperative acute kidney injury (AKI) in adult patients undergoing multiple valve surgery...
