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Adult brainstem glioma: a multicentre retrospective analysis of 47 Italian patients
Background and purposeAdult brainstem gliomas are rare primary brain tumours with heterogeneous clinical course. The low frequency of these tumours...
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Surgery for cerebral cavernous malformations: a systematic review and meta-analysis
BackgroundWe sought to quantify the risks of neurosurgical excision of cerebral cavernous malformations (CCMs) in a systematic review of cohort...
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IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity
BackgroundIMI2-PainCare-BioPain-RCT2 is one of four similarly designed clinical studies aiming at profiling a set of functional biomarkers of drug...
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Postsurgical geometrical variations of tumor bed and brainstem during photon and proton therapy for pediatric tumors of the posterior fossa: dosimetric impact and predictive factors
PurposeBrainstem radionecrosis is an important issue during the irradiation of tumors of the posterior fossa. The aim of the present study is to...
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Fluorescein-guided surgery in high-grade gliomas: focusing on the eloquent and deep-seated areas
PurposeThe vital function of eloquent and deep brain areas necessitates precise treatment for tumors located in these regions. Fluorescein-guided...
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Postoperative trigeminal neuropathy outcomes following surgery for tumors involving the trigeminal nerve
ObjectiveTo observe the evolution and outcomes of postoperative trigeminal neuropathy following surgery of tumor involving the trigeminal nerve.
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Dexmedetomidine versus remifentanil in nasal surgery: a systematic review and meta-analysis
BackgroundNasal surgeries, addressing anatomical variations for form and function, require careful anesthesia administration, including...
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Predictors of extubation failure and prolonged mechanical ventilation among patients with intracerebral hemorrhage after surgery
BackgroundSpontaneous intracerebral hemorrhage (ICH) is a condition associated with high mortality and morbidity. Survivors may require prolonged...
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The precuneal interhemispheric, trans-tentorial corridor to the pineal region and brainstem, surgical anatomy, and case illustration
BackgroundThe pineal region and dorsal midbrain are among the most challenging surgical targets. To approach lesions in this region that harbor a...
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Rapid ossification of a giant post-operative occipital pseudomeningocele following posterior fossa surgery
Pseudomeningocele formation following posterior fossa surgery is a well-recognised complication, occurring in up to 33% of operated cases in some...
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Predictive value of facial motor–evoked potential and electromyography for facial motor function in vestibular schwannoma surgery
PurposeIntraoperative neuromonitoring (IONM) aims to preserve facial nerve (FN) function during vestibular schwannoma (VS) surgery. However, current...
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5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques
PurposeThe aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP)...
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Magnetic resonance imaging of the brainstem in children, part 1: imaging techniques, embryology, anatomy and review of congenital conditions
Part 1 of this series of two articles describes conventional and advanced MRI techniques that are useful for evaluating brainstem pathologies. In...
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Technical note: pre-positioning lower limb SSEP during semi-sitting positioning in posterior fossa surgery- does it matter?
Intra-operative monitoring has been a crucial tool in modern neurosurgery as it allows to optimize surgical outcome whilst reducing neurological...
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Intra-operative hypertension as a predictor of surgical outcomes in microvascular decompression surgery for trigeminal neuralgia
PurposeThe trigeminocardiac reflex (TCR) has traditionally been characterized by a sudden decrease in heart rate, asystole, or hypotension during the...
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Neurogenic stunned myocardium resulting from surgical brainstem handling during resection of paediatric recurrent medulloblastoma—a possible brain heart interaction
BackgroundNeurogenic stunned myocardium (NSM) is characterised by an acute onset cardiac dysfunction following an acute neurological insult which...
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Evaluation of phoneme recognition skills in pediatric auditory brainstem implant users
ObjectivesThis study aims to evaluate the relationship between phoneme recognition skills and language development skills in pediatric auditory...
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Multiparametric prenatal imaging characterization of fetal brain edema in Chiari II malformation might help to select candidates for fetal surgery
ObjectiveTo identify brain edema in fetuses with Chiari II malformation using a multiparametric approach including structural T2-weighted, diffusion...
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Changes in motor evoked potentials after erector spinae block in scoliosis surgery—when to take pre-incision baseline recordings?
Multimodal intraoperative neurophysiological monitoring (IONM) is highly valuable in scoliosis surgeries for monitoring spinal cord function,...
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The role of surgical factors eliciting oculocardiac reflex of patients undergoing orbital tumor surgery: a retrospective study
PurposeOrbital tumors are an interdisciplinary disease, and surgery is one of the main treatment methods. The oculocardiac reflex (OCR) is a...
