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1. Modulation of bone remodeling by the gut microbiota: a new therapy for osteoporosis

   The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being of the host. Recent studies have demonstrated that the...

   Zhengtian Lyu, Yongfei Hu, ... Dan Liu in Bone Research

   Article Open access 09 June 2023
   

2. Targeting aging with the healthy skeletal system: The endocrine role of bone

   Aging is an inevitable biological process, and longevity may be related to bone health. Maintaining strong bone health can extend one’s lifespan, but...

   Xuan-Qi Zheng, Jia-Liang Lin, ... Chun-Li Song in Reviews in Endocrine and Metabolic Disorders

   Article 05 July 2023
   

3. Targeting strategies for bone diseases: signaling pathways and clinical studies

   Since the proposal of Paul Ehrlich’s magic bullet concept over 100 years ago, tremendous advances have occurred in targeted therapy. From the initial...

   Hao Xu, Wentao Wang, ... Dechun Geng in Signal Transduction and Targeted Therapy

   Article Open access 17 May 2023
   

4. Mechanical regulation of bone remodeling

   Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and...

   Lijun Wang, **uling You, ... Weiguo Zou in Bone Research

   Article Open access 18 February 2022
   

5. A mutation in the ZNF687 gene that is responsible for the severe form of Paget’s disease of bone causes severely altered bone remodeling and promotes hepatocellular carcinoma onset in a knock-in mouse model

   Paget’s disease (PDB) is a late-onset bone remodeling disorder with a broad spectrum of symptoms and complications. One of the most aggressive forms...

   Sharon Russo, Federica Scotto di Carlo, ... Fernando Gianfrancesco in Bone Research

   Article Open access 14 March 2023
   

6. Zoledronate treatment exerts sex-independent effects on bone and dental physicochemical properties in mice jaw necrosis

   Introduction

   Bisphosphonate (BF) therapy is strongly related to the occurrence of medication-related osteonecrosis of the jaw (ONJ). However, no...

   Maria Elisa Quezado Lima-Verde, Maria Imaculada de Queiroz Rodrigues, ... Ana Paula Negreiros Nunes Alves in Journal of Bone and Mineral Metabolism

   Article 07 September 2023
   

7. Aging impairs the osteocytic regulation of collagen integrity and bone quality

   Poor bone quality is a major factor in skeletal fragility in elderly individuals. The molecular mechanisms that establish and maintain bone quality,...

   Charles A. Schurman, Serra Kaya, ... Tamara Alliston in Bone Research

   Article Open access 26 February 2024
   

8. Do bone turnover markers reflect changes in bone microarchitecture during treatment of patients with thyroid dysfunction?

   Purpose

   This study aimed to compare changes in the bone turnover markers (BTMs)—C-terminal telopeptide of type I collagen (CTX-I) and procollagen I...

   C. J. Vinther, L. H. Poulsen, ... S. J. Bonnema in Journal of Endocrinological Investigation

   Article 05 September 2022
   

9. Bone-Specific Drug Delivery for Osteoporosis and Rare Skeletal Disorders

   Purpose of Review

   The skeletal system provides an important role to support body structure and protect organs. The complexity of its architecture and...

   Kazuki Sawamoto, J. Víctor Álvarez, ... Shunji Tomatsu in Current Osteoporosis Reports

   Article 26 August 2020
   

10. Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD)

    Background

    Patients with COPD are often affected by loss of bone mineral density (BMD) and osteoporotic fractures. Natriuretic peptides (NP) are known...

    Franziska C. Trudzinski, Rudolf A. Jörres, ... Hubert Wirtz in Respiratory Research

    Article Open access 13 July 2024
    

11. Evaluation of the trabecular bone score in 35 children and adults with X-linked hypophosphatemic rickets

    Introduction

    The aim of this study is to evaluate and compare the trabecular bone scores (TBSs) of 11 children and 24 adults with X-linked...

    Guido de Paula Colares Neto, Rosa Maria Rodrigues Pereira, ... Regina Matsunaga Martin in Journal of Bone and Mineral Metabolism

    Article 07 July 2023

12. Mitochondrial Genetics and Function as Determinants of Bone Phenotype and Aging

    Purpose of Review

    The purpose of this review is to summarize the recently published scientific literature regarding the effects of mitochondrial...

    Sarah E. Catheline, Ethan Kaiser, Roman A. Eliseev in Current Osteoporosis Reports

    Article 05 August 2023
    

13. Machine learning based biomarker discovery for chronic kidney disease–mineral and bone disorder (CKD-MBD)

    Introduction

    Chronic kidney disease-mineral and bone disorder (CKD-MBD) is characterized by bone abnormalities, vascular calcification, and some other...

    Yuting Li, Yukuan Lou, ... **ang Shao in BMC Medical Informatics and Decision Making

    Article Open access 05 February 2024
    

14. Bone healing differences in sexes under ibuprofen treatment

    Bone healing is comprised of a complex cascade of events to repair the fractured bone and gain functionality. This process is affected by numerous...

    Yamin Haghani, Hasan Momeni, Atousa Aminzadeh in Comparative Clinical Pathology

    Article 08 June 2022
    

15. PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging

    Bone marrow adipocytes (BMAds) affect bone homeostasis, but the mechanism remains unclear. Here, we showed that exercise inhibited PCNA...

    Lingqi **e, Yalun Cheng, ... Hui Peng in Bone Research

    Article Open access 04 July 2024
    

16. Gut microbiota as a target in the bone health of livestock and poultry: roles of short-chain fatty acids

    The regulation and maintenance of bone metabolic homeostasis are crucial for animal skeletal health. It has been established that structural...

    Shu-Cheng Huang, Yan-Feng He, ... Aftab Shaukat in Animal Diseases

    Article Open access 20 July 2023
    

17. Role of fibroblast growth factor-23 as an early marker of metabolic bone disease of prematurity

    Purpose

    Metabolic bone disease of prematurity (MBDP) remains a significant cause of morbidity in extremely premature newborns. In high-risk patients,...

    Sandra Llorente-Pelayo, Pablo Docio, ... Domingo González-Lamuño in BMC Pediatrics

    Article Open access 29 June 2024
    

18. Resveratrol Modulates Bone Mineral Density and Bone Mineral Content in A Rat Model of Male Hypogonadism

    Objective

    To determine whether resveratrol (Res) can correct osteoporosis induced in a rat model of male hypogonadism.

    Methods

    Thirty-two rats were...

    Hussein F. Sakr, Boudaka Ammar, ... Basim H. Elesawy in Chinese Journal of Integrative Medicine

    Article 07 July 2022

19. Metabolic Bone Disease in Preterm Neonates With Fetal Growth Restriction (FGR): A Prospective Cohort Study

    Objectives

    To study the association of fetal growth restriction (FGR) with metabolic bone disease in preterm neonates.

    Methodology

    This prospective...

    Guru Prasad Peruri, Ambalakkuthan Murugesan, ... Sadishkumar Kamalanathan in Indian Pediatrics

    Article 20 July 2023

20. Metabolomics analysis of the potential mechanism of Yi-Guan-Jian decoction to reverse bone loss in glucocorticoid-induced osteoporosis

    Background

    Glucocorticoid-induced osteoporosis (GIOP) is a disease in which long-term use of glucocorticoid causes bone loss, deterioration of bone...

    Mengxing Yin, Dezhi Zhou, ... Junmin Li in Journal of Orthopaedic Surgery and Research

    Article Open access 05 June 2023