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The recent research progress in neurobiological characteristics and pain regulation of the cerebrospinal fluid-contacting nucleus
The ependymal epithelium forms the cerebrospinal fluid barrier, separating the brain and spinal cord from the cerebrospinal fluid. However, in...
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Understanding the pathophysiology of acute critical illness: translational lessons from zebrafish models
The models used to investigate the pathophysiological mechanisms of acute critical illness are not limited to mammalian species. The zebrafish ( Danio...
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Psychiatric Evaluation and Management in Pediatric Spinal Cord Injuries: a Review
Purpose of ReviewTo summarize current key recommendations in the evaluation and management of mental health disorders associated with spinal cord...
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Transverse myelitis with positive dengue virus serology: a case report
BackgroundTransverse myelitis is an inflammation of the spinal cord that spreads along the horizontal plane of a section of the spinal cord....
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Autoimmune glial fibrillary acidic protein astrocytopathy in children: a retrospective study
ObjectiveTo describe the clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy in children.
MethodData from 11...
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A rare case report of endovascular management of pediatric spinal arteriovenous malformation
BackgroundSpinal arteriovenous malformations (AVM) consist of a heterogeneous group of pathological vascular entities that affect the spinal cord...
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Successful surgical and medical treatment of a severe, acute epidural bleed in a young dog due to steroid responsive meningitis-arteritis
BackgroundSteroid responsive meningitis-arteritis (SRMA) is an immune-mediated disease of the leptomeninges and its associated blood vessels,...
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Interleukin-31 in serum and cerebrospinal fluid of dogs with syringomyelia
BackgroundSyringomyelia is a spinal cord cavity containing cerebrospinal fluid (CSF)-like fluid. If syringomyelia asymmetrically involves the dorsal...
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Neurosurgical emergencies in spinal tumors: pathophysiology and clinical management
Whether they are spinal metastases or primary spinal neoplasms, spinal tumors cause a myriad of complications given their critical location. Spinal...
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Sonic Hedgehog modulates the inflammatory response and improves functional recovery after spinal cord injury in a thoracic contusion–compression model
PurposeThe Sonic Hedgehog (Shh) pathway has been associated with a protective role after injury to the central nervous system (CNS). We, therefore,...
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Blood–brain barrier dysfunction and myelin basic protein in survival of amyotrophic lateral sclerosis with or without frontotemporal dementia
ObjectiveWe aim to investigate blood–brain barrier (BBB) dysfunction and myelin basic protein (MBP) in amyotrophic lateral sclerosis (ALS) with or...
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Moving towards a new era for the treatment of neuromyelitis optica spectrum disorders
Neuromyelitis optica spectrum disorders (NMOSD) include a rare group of autoimmune conditions that primarily affect the central nervous system. They...
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Autonomic dysfunction in SARS-COV-2 infection acute and long-term implications COVID-19 editor’s page series
AbstractThe autonomic nervous system (ANS) is a complex network of nerves originating in the brain, brain stem, spinal cord, heart and extracardiac...
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Perioperative complications of en bloc resection and anterior column reconstruction for thoracic and lumbar spinal tumors
PurposeTo evaluate the perioperative clinical outcomes of en bloc resection and anterior column reconstruction for thoracolumbar spinal tumors.
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Pathogenic mechanisms underlying itch in atopic dermatitis: the emerging role of neuroimmune interactions
Itch is a frequent dermatological sensation that can occur in a variety of skin conditions, including atopic dermatitis, inflammatory disorders...
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Multiple myeloma presenting as an intramedullary spinal cord tumor: a case report and review of the literature
BackgroundExtramedullary disease in multiple myeloma often portends a worse diagnosis. In approximately 1% of cases, multiple myeloma may metastasize...
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Application of postmortem MRI for identification of medulla oblongata contusion as a cause of death: a case report
Whiplash injury is common in traffic accidents, and severe whiplash is characterized by cervical spinal cord injuries with cervical dislocation or...
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A case report of spinal toxocariasis with extensive tumor-like involvement
BackgroundToxocariasis is a common parasitic infection worldwide. Although it can present as several clinical syndromes, neurological manifestation...
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Anti-ganglioside antibody positive neuromyelitis optica spectrum disorders with peripheral neuropathy: a case report
BackgroundNeuromyelitis optica spectrum disorders (NMOSD) is a group of autoimmune-mediated disorders of the central nervous system primarily...
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Endothelial cells and macrophages as allies in the healthy and diseased brain
Diseases of the central nervous system (CNS) are often associated with vascular disturbances or inflammation and frequently both. Consequently,...
