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Hepatectomy is Beneficial in Select Patients with Multiple Hepatocellular Carcinomas
BackgroundA single hepatocellular carcinoma (HCC) is a good indication for hepatic resection regardless of tumor size, but the surgical indications...
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Efficacy and safety of lenvatinib plus PD-1 inhibitor with or without transarterial chemoembolization in unresectable hepatocellular carcinoma
PurposeTo compare the clinical benefit and tolerability of triple therapy of lenvatinib, programmed death 1 (PD-1) inhibitor, and transarterial...
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Transferrin Receptor is Associated with Sensitivity to Ferroptosis Inducers in Hepatocellular Carcinoma
PurposeTransferrin receptor (TFR), a membrane protein that has a critical role in the transport of iron into cells, is known to be a...
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Identification of immune-related target and prognostic biomarkers in PBMC of hepatocellular carcinoma
BackgroundHepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset,...
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Can alternative liver function scores facilitate the establishment of an indication for radioablative therapy in patients with hepatocellular carcinoma?
Background and purposeALBI and IBI are new scores to evaluate the liver function in patients with hepatocellular carcinoma (HCC). The purpose of this...
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Resubclassification and clinical management for Barcelona Clinic Liver Cancer Stage C hepatocellular carcinoma
BackgroundPatients with Barcelona Clinic Liver Cancer Stage C (BCLC-C) hepatocellular carcinoma (HCC) can be markedly heterogeneous with varying...
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Prognosis prediction and risk stratification of transarterial chemoembolization or intraarterial chemotherapy for unresectable hepatocellular carcinoma based on machine learning
ObjectiveTo develop and validate a risk scoring scale model (RSSM) for stratifying prognostic risk after intra-arterial therapies (IATs) for...
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MRI-Derived Sarcopenia Associated with Increased Mortality Following Yttrium-90 Radioembolization of Hepatocellular Carcinoma
PurposeTo evaluate the influence of sarcopenia on survival in patients with hepatocellular carcinoma (HCC) treated with 90 Y radioembolization.
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A comprehensive preoperative predictive score for post-hepatectomy liver failure after hepatocellular carcinoma resection based on patient comorbidities, tumor burden, and liver function: the CTF score
BackgroundPost-hepatectomy liver failure (PHLF) is a dreaded complication following liver resection for hepatocellular carcinoma (HCC) with a high...
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Maximum tumor-absorbed dose measured by voxel-based multicompartmental dosimetry as a response predictor in yttrium-90 radiation segmentectomy for hepatocellular carcinoma
ObjectiveAdvances in hepatic radioembolization are based on a selective approach with radical intent and the use of multicompartment dosimetric...
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Risk Factors Affecting the Recurrence-Free Survival of Hepatocellular Carcinoma After Hepatectomy: a Meta-analysis
This study aims to investigate the risk factors affecting the recurrence-free survival of hepatocellular carcinoma after hepatectomy and to provide...
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Postoperative survival analysis of hepatocellular carcinoma patients with liver cirrhosis based on propensity score matching
ObjectiveMost hepatocellular carcinoma (HCC) patients in China have some degree of liver cirrhosis. The effect of cirrhosis on the long-term...
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Current status of primary liver cancer and decompensated cirrhosis in Japan: launch of a nationwide registry for advanced liver diseases (REAL)
BackgroundWe developed a nationwide database that stores data of patients with primary liver cancer (PLC) and decompensated cirrhosis (DC) on an...
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Surgical and oncological outcomes of hepatic resection for BCLC-B hepatocellular carcinoma: a retrospective multicenter analysis among 474 consecutive cases
The Barcelona clinic liver cancer (BCLC) algorithm is the most widely accepted staging system form hepatocellular carcinoma (HCC). Liver resection is...
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Lenvatinib for the treatment of hepatocellular carcinoma—a real-world multicenter Australian cohort study
IntroductionHepatocellular carcinoma (HCC) is a serious complication of chronic liver disease. Lenvatinib is an oral multikinase inhibitor registered...
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Prognostic Advantages of Individual Additional Interventions After Lenvatinib Therapy in Patients with Advanced Hepatocellular Carcinoma
BackgroundIncreasing number of patients with advanced hepatocellular carcinoma (HCC) has recently achieved salvage interventions after introduction...
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Ipilimumab and nivolumab in advanced hepatocellular carcinoma after failure of prior immune checkpoint inhibitor-based combination therapies: a multicenter retrospective study
IntroductionImmune checkpoint inhibitor (ICI)-based regimens are transforming the landscape of hepatocellular carcinoma (HCC) treatment. We describe...
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Clinical impact of sarcopenia in early-stage intrahepatic recurrent hepatocellular carcinoma: an association with impaired host immunity
PurposeThis study investigated the role of sarcopenia in the long-term outcomes of patients with early-stage intrahepatic recurrent hepatocellular...
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A Practical Risk Classification of Early Recurrence in Hepatocellular Carcinoma Patients with Microvascular invasion after Hepatectomy: A Decision Tree Analysis
PurposeThis study was designed to establish risk classifications for early recurrence in hepatocellular carcinoma (HCC) patients with microvascular...
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Changes in the Role and Mode of Liver Resection for Hepatocellular Carcinoma Over 20 Years: A Single-Center Analysis
IntroductionThe aim of this study was to analyze changes in characteristics of HCC and the modes of LR over 20 years in order to show the impact of...
