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Developmental validation study of a 24-plex Y-STR direct amplification system for forensic application
In the present study, validation data for 24 Y-STR loci from the Microreader™ 24Y Direct ID System was presented. Eight Y-STR loci have PCR product...
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Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India
We report here the first ever global study on genetic polymorphism using a Verifiler Plus TM autosomal STR multiplex system. The study evaluated...
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Molar pregnancy unveiled by DNA profiling: a rare forensic case study
BackgroundForensic DNA analysis is one of the most advanced tools in the criminal investigation. It is used successfully in solving offenses...
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Challenges in the recovery of the genetic data from human remains found on the Western Balkan migration route
Traditional DNA-based identification of human remains relies on the system of matching STR profile of the deceased with the family references or...
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Key genetic and forensic attributes of Uttarakhand population of India
The present study aimed to investigate the genetic and forensic attributes of Uttarakhand population based on 20 autosomal STR loci implemented in...
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Full-sibling allelic frequency and sharing among Madurese: STR technique by 12 locus and the sex-ty** amelogenin gene
BackgroundSibling relation over chosen STR loci and localized database is yet to be developed in Indonesia like into many other countries despite the...
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Comparison of DNA preservation between ribs and vertebrae
AbstractThe choice of skeletal element types and their intra-bone parts is important because of differences in DNA preservation, and this must be...
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Discrimination of monozygotic twins using mtDNA heteroplasmy through probe capture enrichment and massively parallel sequencing
Differentiating between monozygotic (MZ) twins remains difficult because they have the same genetic makeup. Applying the traditional STR genoty**...
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Characterisation, verification and genetic basis of anomalous STR patterns: a report of four cases of X-chromosome STR biallelic patterns in human males
Analysis of the characteristics and genetic basis of the anomalous short tandem repeat (STR) pattern encountered in forensic cases has been shown to...
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Development of a multiplex panel with 36 insertion/deletion markers (InDel) for individual identification
In recent years, the insertion/deletion (InDel) polymorphism has become a preferred genetic marker in forensic genetics due to its low mutation rates...
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A novel mutation at the AMEL primer binding region on the Y chromosome in AMELY negative male
Gender identification in forensic DNA ty** is an important tool for criminal investigation as well as STR ty**. Most methods are based on a size...
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STR technique for the detection of contamination by exogenous DNA in paraffin blocks and histological slides
Gastrointestinal Stromal Tumors (GIST) present different types of mutations that may or may not be sensitive to specific target therapy. The...
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Detecting genetic hypermutability of gastrointestinal tumor by using a forensic STR kit
Growing evidence suggests that somatic hypermutational status and programmed cell death-1 overexpression are potential predictive biomarkers...
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Population data for 21 autosomal STR loci (GlobalFiler kit) in two Mexican-Mestizo population from the northwest, Mexico
Mexican Mestizos (admixed) have been poorly studied for short tandem repeats (STRs) included for new human identification (HID) kits, such as the...
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A novel approach for rapid cell assessment to estimate DNA recovery from human bone tissue
We report on the use of a DNA staining dye to locate and record nucleated osteocytes and other bone-related cells within sections of archived...
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Linkage, recombination, and mutation rate analyses of 19 X-chromosomal STR loci in Chinese Southern Han pedigrees
From Southern Han Chinese samples, we analyzed 19 X-STR markers for linkage, linkage disequilibrium (LD), and mutation rate. The data were collected...
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Genetic polymorphisms of 21 autosomal STR loci in Chinese Uygur ethnic population
Genetic polymorphisms of 21 short tandem repeat (STR) loci were studied in 576 unrelated Uygur individuals living in Urumqi using Goldeneye™ DNA ID...
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A four-step mutation at D22S1045 in one complex paternity case when the brother of the alleged father hypothesis is evaluated
We report one complex paternity case presenting a presumable paternal four-step STR mutation between the alleged father (AF) and child; the...
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Mutated Toll-like receptor 9 increases Alzheimer’s disease risk by compromising innate immunity protection
The development of Alzheimer’s disease (AD) involves central and peripheral immune deregulation. Gene identification and studies of AD genetic...
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Comparison between various DNA sterilization procedures applied in forensic analysis
BackgroundThe advanced sensitive STR kits applied in forensic DNA ty** techniques can cause challenging issues when evidence samples are...
